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New method enhances efficiency and accuracy of single cell RNA sequencing

In the era of personalized medicine, scientists are using new genetic and genomic insights to help them determine the best treatment for a given patient. In the case of cancer, the first step toward these treatments is an investigation into how tumor cells behave in an effort to figure out the best drugs to use to attack them.

22 Nov 2018

UMN researchers focus on improving dermatologic care for sexual and gender minority patients

University of Minnesota researchers recently published an opinion piece in JAMA Dermatology focused on standardizing collection of sexual orientation and gender identity in dermatology clinical settings.

22 Nov 2018

Researchers to develop computer-based tools for use in cancer research

The doctoral program 'CompCancer - Computational Methods in Oncology: Towards Personalized Medicine in Cancer Therapies' has received approval from the German Research Foundation.

21 Nov 2018

Brain imaging study reveals 'hot spot' for cue-reactivity in substance users

When patients with dependence on alcohol, cocaine or nicotine are shown drug cues, or images related to the substance, an area of their brain known as the medial prefrontal cortex shows increased activity, report investigators at the Medical University of South Carolina in an article published online September 7, 2018 in Translational Psychiatry.

21 Nov 2018

First modeling system developed for testing age-specific human immune responses to vaccines

A team of scientists at Boston Children's Hospital has developed the first modeling system for testing age-specific human immune responses to vaccines -- outside the body. The practical, cost-effective new platform, using all human components, is expected to accelerate and de-risk the development, assessment and selection of vaccines.

20 Nov 2018

Potential new therapeutic approach developed for synovial sarcoma

Scientists have developed a potential new therapeutic approach for synovial sarcoma, one of the most common soft-tissue cancers in teenagers and young adults.

20 Nov 2018

Improving dementia treatment and staff training in care homes saves thousands of pounds per year

Improving staff training in care homes and reducing reliance on harmful medications saves thousands of pounds per year, as well as improving quality of life and reducing agitation in dementia, new research has demonstrated.

20 Nov 2018

Abramson Cancer Center becomes the 28th member institution of National Comprehensive Cancer Network

The Abramson Cancer Center (ACC) at the University of Pennsylvania announced today that it is joining the National Comprehensive Cancer Network (NCCN) as its 28th member institution.

20 Nov 2018

Scientists identify novel target for neuron regeneration, functional recovery in spinal cord injury

Restoring the ability to walk following spinal cord injury requires neurons in the brain to reestablish communication pathways with neurons in the spinal cord.

20 Nov 2018

Study warns that potential epigenetic therapy may boost lung cancer stem cells

Epigenetic therapies -- targeting enzymes that alter what genes are turned on or off in a cell -- are of growing interest in the cancer field as a way of making a cancer less aggressive or less malignant.

20 Nov 2018

Study evaluates second-hand marijuana smoke exposure among children

In a study designed to evaluate second-hand marijuana smoke exposure among children--a topic that scientists have not yet widely addressed--researchers at the Icahn School of Medicine at Mount Sinai found that nearly half of children whose parents smoked marijuana showed evidence of second-hand marijuana smoke exposure.

20 Nov 2018

Storage failures of eggs and embryos gain a new perspective

On March 3, 2018, a liquid nitrogen storage tank at the University Hospitals Fertility Center in Cleveland failed. Dr. Eli Adashi, a professor of medical science at Brown University's Warren Alpert Medical School, characterized the event as a "tragic accident" in which 950 patients lost more than 4,000 frozen eggs and embryos.

20 Nov 2018

Cessation fatigue predicts relapse rate after attempts to quit smoking

Although there is good news about smoking -- only 14 percent of Americans smoke, the lowest number ever, according to a 2017 National Health Interview Survey -- challenges remain. In a given year, more than 40 percent of smokers make no attempt to quit.

20 Nov 2018

Towards finding a druggable cancer target

It's known that cancer involves unchecked cell growth and that a biological pathway that regulates organ size, known at the Hippo pathway, is also involved in cancer.

19 Nov 2018

RNAi therapy shown to alleviate preeclampsia in animal model

Researcher have used a small interfering RNA (siRNA) to reduce preeclampsia symptoms in an animal model. The approach could provide a new way of treating preeclampsia in humans.

19 Nov 2018

New strategy to hinder emergence of antimicrobial-resistant pathogens

With many disease-causing bacteria ratcheting up their shields against current drugs, new tactics are vital to protect people from treatment-resistant infections.

17 Nov 2018

Researchers find metabolite shuttle between cells in the liver that may combat tissue fibrosis

University of Minnesota Medical School researchers have made a discovery which could lead to a new way of thinking about how disease pathogenesis in the liver is regulated, which is important for understanding the condition nonalcoholic fatty liver disease, which is incredibly common and growing.

16 Nov 2018

Expert suggests ways to control uncomfortable vaginal symptoms in diabetic women

With approximately 9.7 million women in the U.S. suffering with diabetes and almost 50 million U.S. adults with prediabetes, most of the women are experiencing uncomfortable vaginal symptoms like recurrent yeast and bacterial infections, vaginal dryness, reduced sexual interest, and painful intercourse that can adversely affect quality of life.

15 Nov 2018

Researchers develop tool that speeds up analysis and publication of biomedical data

Researchers at the Icahn School of Medicine at Mount Sinai have developed a tool that speeds up the analysis and publication of biomedical data from many months or years to mere minutes, transforming the way researchers communicate results of their studies.

15 Nov 2018

Regular head circumference assessment of preterm babies can help identify long-term IQ problems

Regular early head circumference assessments add valuable information when screening for long-term neurocognitive risk - according to new research by an international research collaboration, including the University of Warwick, UK and the University of Tennessee Knoxville, US.

14 Nov 2018

Medical School News and Research

New method enhances efficiency and accuracy of single cell RNA sequencing

UMN researchers focus on improving dermatologic care for sexual and gender minority patients

Researchers to develop computer-based tools for use in cancer research

Brain imaging study reveals 'hot spot' for cue-reactivity in substance users

First modeling system developed for testing age-specific human immune responses to vaccines

Potential new therapeutic approach developed for synovial sarcoma

Improving dementia treatment and staff training in care homes saves thousands of pounds per year

Abramson Cancer Center becomes the 28th member institution of National Comprehensive Cancer Network

Scientists identify novel target for neuron regeneration, functional recovery in spinal cord injury

Study warns that potential epigenetic therapy may boost lung cancer stem cells

Study evaluates second-hand marijuana smoke exposure among children

Storage failures of eggs and embryos gain a new perspective

Cessation fatigue predicts relapse rate after attempts to quit smoking

Towards finding a druggable cancer target

RNAi therapy shown to alleviate preeclampsia in animal model

New strategy to hinder emergence of antimicrobial-resistant pathogens

Researchers find metabolite shuttle between cells in the liver that may combat tissue fibrosis

Expert suggests ways to control uncomfortable vaginal symptoms in diabetic women

Researchers develop tool that speeds up analysis and publication of biomedical data

Regular head circumference assessment of preterm babies can help identify long-term IQ problems

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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