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Alnylam presents positive Phase 1 ALN-AT3 trial results in hemophilia at ISTH 2015 Congress

Additional study results from 12 hemophilia A and B subjects demonstrated that subcutaneous administration of ALN-AT3 achieved potent and dose-dependent knockdown of AT of up to 86%. AT knockdown was highly durable, with effects lasting over two months after the last dose, supporting further evaluation of a once-monthly subcutaneous dose regimen.

24 Jun 2015

Climate change poses medical emergency, threatens 50 years of gains in global health

Climate change is a “medical emergency” says Commission author, but tackling it could be the greatest global health opportunity of the 21st century

23 Jun 2015

Israeli researchers establish novel optogenetic method for cardiac pacing and resynchronization

Israeli researchers have successfully established a new approach for pacing the heart and synchronizing its mechanical activity without the use of a conventional electrical pacemaker. This novel biologic strategy employs light-sensitive genes that can be injected into the heart and then activated by flashes of blue light.

23 Jun 2015

Cardiac device wearers ought to keep safe distance from smartphones to prevent unwanted painful shocks

Cardiac device wearers should keep a safe distance from smartphones to avoid unwanted painful shocks or pauses in function, reveals research presented today at EHRA EUROPACE -- CARDIOSTIM 2015 by Dr. Carsten Lennerz, first author and cardiology resident in the Clinic for Heart and Circulatory Diseases, German Heart Centre, Munich, Germany.

22 Jun 2015

Pediatric study looks at evidence-based predictors of biphasic allergic reactions

Children are more likely to have a repeat, delayed anaphylactic reaction from the same allergic cause, depending on the severity of the initial reaction. The first pediatric study to look at the predictors for this phenomenon was published today in Annals of Allergy, Asthma & Immunology.

22 Jun 2015

Understanding how humans and animals perceive the auditory world

Sit down with a friend in a quiet restaurant and begin talking, just before the dinner crowd's arrival. Business is slow at first, but picks up quickly, just like the sound level. Music plays, glasses clink, servers discuss specials. Discussions are everywhere, colliding and competing with the other noises.

19 Jun 2015

UNC Lineberger scientists contribute to better understanding of genetic mutations in melanoma

UNC Lineberger Comprehensive Cancer Center researchers have significantly contributed to a better understanding of the genetic alterations found in cutaneous melanoma, the most lethal form of skin cancer, as part of a multi-institution, international effort of The Cancer Genome Atlas.

19 Jun 2015

Effective medical communication missing between physicians and patients with chronic migraine

Many patients with chronic migraine (CM) receive suboptimal medical treatment even when they seek medical care. Reporting at the annual scientific meeting of the American Headache Society, researchers found that the majority of clinical encounters between CM patients and physicians were missing essential components of effective communication.

19 Jun 2015

CGRP monoclonal antibodies show promise in treating migraine

Migraine researchers and clinicians are growing excited about a new class of drugs called Calcitonin Gene-Related Peptide (CGRP) monoclonal antibodies, which are showing promise in treating high-frequency episodic migraine and chronic migraine.

17 Jun 2015

DCRI announces new study to better understand lipid management

At a time when lipid management in the United States is undergoing transition in response to new guideline recommendations and expanding lipid-lowering therapy options, the Duke Clinical Research Institute (DCRI) today announced a new study to better understand contemporary lipid management as well as the beliefs and attitudes of patient and providers regarding cholesterol, cardiovascular risk assessment, and options for lipid treatments.

17 Jun 2015

Kaiser Permanente wins 2015 CIO 100 Award for using health IT to improve quality and care delivery

Kaiser Permanente recently was honored by IDG's CIO magazine as one of the 2015 CIO 100 award winners for using technology to improve the health care experience for patients and their families.

16 Jun 2015

$Medical guidance lacking on how to care for elderly hip fracture patients with dementia$

Medical guidance lacking on how to care for elderly hip fracture patients with dementia

Medical guidance on how to care for elderly people with dementia following a hip fracture is 'sadly lacking' according to researchers at the University of East Anglia.

15 Jun 2015

Peanut and nut intake lowers risk of dying from major causes of death

A paper published today in the International Journal of Epidemiology confirms a link between peanut and nut intake and lower mortality rates, but finds no protective effect for peanut butter. Men and women who eat at least 10 grams of nuts or peanuts per day have a lower risk of dying from several major causes of death than people who don't consume nuts or peanuts.

11 Jun 2015

Tioga Pharmaceuticals announces commencement of asimadoline Phase 2 study for treatment of pruritus

Tioga Pharmaceuticals, a clinical stage biotechnology company, today announced the initiation of a Phase 2 clinical study of asimadoline, a novel, well-studied kappa-opioid receptor specific agonist, for the treatment of pruritus or itching. The double-blind, placebo-controlled clinical study is designed to evaluate the safety, tolerability, and clinical efficacy of asimadoline in patients with pruritus due to atopic dermatitis and is being conducted at 20 clinical study centers in the United States.

11 Jun 2015

Brain changes reflect higher risk of cerebrovascular disease in women who experience more hot flashes

Women who experience more hot flashes, particularly while sleeping, during the menopause transition are more likely to have brain changes reflecting a higher risk for cerebrovascular disease, such as stroke and other brain blood flow problems, according to a pilot study led by researchers at the University of Pittsburgh School of Medicine published online today in Menopause and funded by the National Institutes of Health.

11 Jun 2015

Men benefit from ultrasound screening for abdominal aortic aneurysms

Men benefit from one-time screening for abdominal aortic aneurysms via ultrasound. Studies provide proof that their risk of dying is reduced, the abdominal aorta ruptures less often, and emergency surgery can be avoided more often. Far fewer data are available for women and they show no relevant differences between the groups investigated.

11 Jun 2015

INS announces winners of inaugural best abstract competition at 12th World Congress

The International Neuromodulation Society (INS) announced winners today of its inaugural best abstract competition at the 12th World Congress in Montreal.

10 Jun 2015

International Neuromodulation Society recognizes third Giant of Neuromodulation

The International Neuromodulation Society recognized its third Giant of Neuromodulation at its 12th World Congress in Montreal in June - the first such awardee who is renowned for work in neuromodulation for movement disorder. The honor was given to Prof. Alim-Louis Benabid, MD, PhD, board chairman of the biomedical research center Clinatec in Grenoble.

10 Jun 2015

RFID smart cabinet systems make headway into healthcare

Radio frequency identification (RFID) is rapidly making headway into the healthcare and pharmaceutical industries, especially in assets tracking, supply chain management, and inventory management. In particular, the need for inventory management to reduce instances of loss or misplacement of medical equipment, supplies or drugs, along with efforts to minimise errors and improve patient safety, drives the market for RFID smart cabinet systems.

10 Jun 2015

$Full clinical trial feasible in refractory chronic angina pectoris$

Full clinical trial feasible in refractory chronic angina pectoris

Results of the world's first publicly funded randomized controlled clinical trial of spinal cord stimulation, being presented today at the 12th World Congress of the International Neuromodulation Society, conclude that a fully powered clinical trial is feasible in refractory chronic angina pectoris, a disabling and persistent chronic pain condition.

10 Jun 2015

Frequency News and Research

Alnylam presents positive Phase 1 ALN-AT3 trial results in hemophilia at ISTH 2015 Congress

Climate change poses medical emergency, threatens 50 years of gains in global health

Israeli researchers establish novel optogenetic method for cardiac pacing and resynchronization

Cardiac device wearers ought to keep safe distance from smartphones to prevent unwanted painful shocks

Pediatric study looks at evidence-based predictors of biphasic allergic reactions

Understanding how humans and animals perceive the auditory world

UNC Lineberger scientists contribute to better understanding of genetic mutations in melanoma

Effective medical communication missing between physicians and patients with chronic migraine

CGRP monoclonal antibodies show promise in treating migraine

DCRI announces new study to better understand lipid management

Kaiser Permanente wins 2015 CIO 100 Award for using health IT to improve quality and care delivery

Medical guidance lacking on how to care for elderly hip fracture patients with dementia

Peanut and nut intake lowers risk of dying from major causes of death

Tioga Pharmaceuticals announces commencement of asimadoline Phase 2 study for treatment of pruritus

Brain changes reflect higher risk of cerebrovascular disease in women who experience more hot flashes

Men benefit from ultrasound screening for abdominal aortic aneurysms

INS announces winners of inaugural best abstract competition at 12th World Congress

International Neuromodulation Society recognizes third Giant of Neuromodulation

RFID smart cabinet systems make headway into healthcare

Full clinical trial feasible in refractory chronic angina pectoris

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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