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Combination immunotherapy outperforms durvalumab monotherapy in neoadjuvant NSCLC

Combination immunotherapy with the anti-PD-L1 monoclonal antibody durvalumab and other novel agents outperforms durvalumab alone in the neoadjuvant (pre-surgical) setting for early-stage non-small-cell lung cancer (NSCLC), according to researchers at The University of Texas MD Anderson Cancer Center.

14 Sep 2023

Specialized gut immune cells could be new biomarker for IBD progression

Researchers at the Francis Crick Institute, King's College London and Guy's and St Thomas' NHS Foundation Trust have characterised a specialised type of immune cell, which plays a key role in protecting and repairing the cells in the healthy human gut.

14 Sep 2023

MIT study reveals why immunotherapy doesn't work for all cancer patients

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14 Sep 2023

NIH awards $3.2 million to study how unique DNA circles drive deadly pediatric brain tumors

Lukas Chavez, Ph.D., has received $3.2 million from the National Institutes of Health to study how unique DNA circles found in cancer cells drive deadly pediatric brain tumors.

14 Sep 2023

New trial shows promise of combination neoadjuvant immunotherapy for lung cancer

Patients with stage 1–3 non-small cell lung cancer (NSCLC) given a combination immunotherapy prior to surgery (neoadjuvant) had a better major pathological response (10% or less residual cancer) when the cancer was removed than those who took a single immunotherapy agent alone, according to results of a novel multicenter phase 2 NeoCOAST platform trial that included two investigators from the Johns Hopkins Kimmel Cancer Center and its Bloomberg-Kimmel Institute for Cancer Immunotherapy.

14 Sep 2023

Reviving reservoirs: new findings shake up HIV treatment understanding

Researchers provide insight into the interaction between T lymphocytes and persisting reservoirs of HIV, with repercussions for harnessing effective, long-lasting responses to HIV eradication.

14 Sep 2023

MRI innovation to unveil iron homeostasis in the human brain

Researchers demonstrated a MRI method sensitive to the live brain's iron homeostasis (the r1-r2 extent of relaxation or relaxivity).

14 Sep 2023

Results from a nested randomized controlled trial for BCG vaccination against recurrent herpes labialis

Researchers examined the effect of Bacillus Calmette-Guérin (BCG) vaccination on attenuating herpes labialis (cold sore) recurrences.

14 Sep 2023

AACR Cancer Progress Report provides latest statistics on cancer research and treatment

Today, the American Association for Cancer Research (AACR) released the 13th edition of its annual Cancer Progress Report, which chronicles how basic, translational, and clinical cancer research and cancer-related population sciences - primarily supported by federal investments in the National Institutes of Health (NIH) and the National Cancer Institute (NCI) - remain vitally important to improving health and saving lives.

13 Sep 2023

International experts discuss recent advances in the diagnosis and treatment of atrial fibrillation

Recent advances in the diagnosis and treatment of atrial fibrillation, and what they mean for patients, were considered by a group of around 75 international experts at a three-day meeting that began on Monday.

13 Sep 2023

Dormant HIV reservoirs can spontaneously produce RNA and proteins, study finds

HIV anti-retroviral therapy is considered a treatment and not a cure because patients usually carry a reservoir of HIV-infected cells that can re-emerge if treatment stops.

13 Sep 2023

Researchers receive £2.66M to test new immunotherapeutic strategy for non-small cell lung cancer

University of Liverpool researchers have secured £2.66m Medical Research Council funding to clinically test a novel immunotherapeutic strategy for non-small cell lung cancer – one of the most deadly cancers.

13 Sep 2023

Pregnant smokers who use e-cigarettes more likely to quit smoking later in pregnancy

The risks of smoking during pregnancy for both maternal and fetal health are well documented, but only about half of pregnant people quit smoking on their own.

13 Sep 2023

Revolutionizing sleep apnea care: Mount Sinai's automated tool predicts mortality risk

Researchers propose ventilatory burden (VB) as an automated measure of obstructive sleep apnea severity and a predictor of cardiovascular disease and any-cause mortality.

13 Sep 2023

Can yoga alleviate rheumatoid arthritis severity?

A recent Scientific Reports study investigated the effect of yoga on rheumatoid arthritis (RA) severity.

13 Sep 2023

Comparing HIV PrEP medications: Study explores hypertension risk in adults on TAF vs. TDF

The risk of hypertension and statin initiation in adults starting Human Immunodeficiency Virus Pre-exposure prophylaxis.

13 Sep 2023

A combination of inhibitors may suppress tumor growth and prevent cancer relapse

An international team of researchers has demonstrated that a combination of inhibitors may suppress tumor growth and prevent relapse in patients with certain cancers, including head and neck squamous cell carcinoma and lung adenocarcinoma.

12 Sep 2023

American College of Cardiology launches new campaign to increase diagnostic LDL screening

The American College of Cardiology, through a strategic collaboration with Amgen and Esperion, is launching a new quality improvement campaign, "Driving Urgency in LDL Screening," to increase the rate of diagnostic LDL screening in patients without a prior cardiac event as well as those with known cardiovascular disease to help clinicians identify those who need treatment in accordance with medical guidelines.

12 Sep 2023

Intensity-modulated radiation therapy reduces radiation exposure to heart and lungs in NSCLC patients

Intensity-modulated radiation therapy (IMRT) should be the preferred choice when treating patients with locally advanced non-small cell lung cancer (NSCLC), as it reduces radiation exposure to the heart and lungs, according to researchers at The University of Texas MD Anderson Cancer Center.

12 Sep 2023

Arf1 inhibition induces tumor regression by promoting T cell infiltration

In recent years, cancer immunotherapies, represented by immune checkpoint blockade (ICB), have been highly successful and have become an important basis for the future treatment of cancers.

12 Sep 2023

Therapy News and Research

Combination immunotherapy outperforms durvalumab monotherapy in neoadjuvant NSCLC

Specialized gut immune cells could be new biomarker for IBD progression

MIT study reveals why immunotherapy doesn't work for all cancer patients

NIH awards $3.2 million to study how unique DNA circles drive deadly pediatric brain tumors

New trial shows promise of combination neoadjuvant immunotherapy for lung cancer

Reviving reservoirs: new findings shake up HIV treatment understanding

MRI innovation to unveil iron homeostasis in the human brain

Results from a nested randomized controlled trial for BCG vaccination against recurrent herpes labialis

AACR Cancer Progress Report provides latest statistics on cancer research and treatment

International experts discuss recent advances in the diagnosis and treatment of atrial fibrillation

Dormant HIV reservoirs can spontaneously produce RNA and proteins, study finds

Researchers receive £2.66M to test new immunotherapeutic strategy for non-small cell lung cancer

Pregnant smokers who use e-cigarettes more likely to quit smoking later in pregnancy

Revolutionizing sleep apnea care: Mount Sinai's automated tool predicts mortality risk

Can yoga alleviate rheumatoid arthritis severity?

Comparing HIV PrEP medications: Study explores hypertension risk in adults on TAF vs. TDF

A combination of inhibitors may suppress tumor growth and prevent cancer relapse

American College of Cardiology launches new campaign to increase diagnostic LDL screening

Intensity-modulated radiation therapy reduces radiation exposure to heart and lungs in NSCLC patients

Arf1 inhibition induces tumor regression by promoting T cell infiltration

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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