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Activation of brown fat increases heart-related mortality during winter

More people die from heart-disease during the winter months, and according to a new study published in the journal Cell Metabolism, the increase in mortality is possibly due to the accelerated growth of atherosclerotic plaque in the blood vessels caused by the activation of brown fat by the cold.

3 Jul 2013

Salsalate lowers blood glucose and improves glycemic control in T2D, say scientists

Joslin scientists report that salsalate, a drug used to treat arthritis, lowers blood glucose and improves glycemic control in type 2 diabetes. These findings, which were published today by the Annals of Internal Medicine, provide additional evidence that salsalate may be an effective drug to treat type 2 diabetes.

3 Jul 2013

FDA-approved formoterol drug improves cognitive function in mouse model of Down syndrome

An existing FDA-approved drug improves cognitive function in a mouse model of Down syndrome, according to a new study by researchers at the Stanford University School of Medicine.

3 Jul 2013

Researchers find NRF2 signaling plays a role in growth of tumor cells by altering metabolic pathways

Cancer cells have alteration in metabolic pathways as a result of oncogenes that promote tumor growth. NRF2 (nuclear factor erythroid-derived 2-related factor 2) works as a "master gene" that turns on stress response by increasing numerous antioxidants and pollutant-detoxifying genes to protect the lungs from variety of air pollutants such as diesel exhaust and cigarette smoke.

3 Jul 2013

Devon Medical gets ANVISA certification for extriCARE 2400 NPWT system

Devon Medical, a global medical device manufacturer, designer, and distributor, announced today that it has received medical device registration and approval from the Brazilian National Health Surveillance Agency (ANVISA - Agência Nacional de Vigilância Sanitária) for its extriCARE 2400 Negative Pressure Wound Therapy pump.

2 Jul 2013

First Edition: July 2, 2013

Today's headlines include various reports about changes afoot in the insurance marketplace.

2 Jul 2013

Study finds that long-term cannabis use affects motivation

Long-term cannabis users tend to produce less dopamine, a chemical in the brain linked to motivation, a study has found.

2 Jul 2013

ARIAD Pharmaceuticals' Iclusig gets EC marketing authorization for CML and Ph+ ALL treatment

ARIAD Pharmaceuticals, Inc. today announced that the European Commission has granted a marketing authorization for Iclusig (ponatinib) as an orphan medicinal product for two indications.

2 Jul 2013

UCLA researchers introduce gene therapy technique to treat sickle cell disease

Researchers at UCLA's Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research have successfully established the foundation for using hematopoietic (blood-producing) stem cells from the bone marrow of patients with sickle cell disease to treat the disease.

2 Jul 2013

Nanofiber Solutions wins Ohio Third Frontier Technology Validation and Start-up Fund award

Nanofiber Solutions, LLC, in collaboration with Gail E. Besner, MD, chief of Pediatric Surgery, program director of the Residency in Pediatric Surgery and co-director of the Burn Program all at Nationwide Children's Hospital, recently was honored with the Ohio Third Frontier Technology Validation and Start-up Fund award.

2 Jul 2013

RLI awards scholarships to 10 residents to attend RLI Annual Event

The American College of Radiology (ACR) Radiology Leadership Institute (RLI) has awarded scholarships to 10 residents enabling them to attend the RLI Annual Event, July 25-28, 2013, at the Kellogg School of Management on Northwestern University's Evanston, IL, campus.

2 Jul 2013

Research roundup: 'Welcome-mat' effect of Medicaid expansion; Setting up shops; California's transition to Medicaid managed care

The number of people eligible for Medicaid who remain uninsured varies from state to state, according to the authors. But the federal health law is likely to increase the rate of enrollment for this group. The potential impact of this increase in Medicaid enrollment, also known as the 'welcome-mat' effect, is unclear.

2 Jul 2013

UH and Case Western Reserve University to develop diagnostic tests to determine HIV drug resistance

Case Western Reserve University has signed an exclusive worldwide licensing agreement granting University Hospitals Case Medical Center rights to a series of diagnostic tests to determine drug resistance and co-receptor tropism in human immunodeficiency virus.

2 Jul 2013

Osteoarthritis associated genes: an interview with Professor Jonathan Tobias, University of Bristol

Joints are lined by articular cartilage, loss of which is one of the hallmarks of osteoarthritis. Articular cartilage is made up of a number of proteins, such as type II collagen. In rare forms of osteoarthritis, one of these structural proteins is defective as a result of a genetic mutation.

2 Jul 2013

Parents, children should leave fireworks displays to experts, say Vanderbilt specialists

Vanderbilt specialists are urging parents and children to leave the fireworks displays to the experts this Fourth of July.

2 Jul 2013

FDA sends Complete Response Letter to Merck regarding investigational drug for insomnia

Merck, known as MSD outside the United States and Canada, announced today that the company has received a Complete Response Letter from the U.S. Food and Drug Administration (FDA) regarding the New Drug Application for suvorexant, Merck's investigational medicine for the treatment of insomnia.

2 Jul 2013

Lawmakers gird for new abortion fight as Texas special session convenes

Texas lawmakers resume debate on proposed abortion legislation as the state legislature opens a special session Monday. Republicans say they will quickly pass new abortion restrictions despite opponents' efforts. Meanwhile, the Congressional Budget Office projected that a House bill that would ban abortions after 20 weeks would increase Medicaid costs by as much as $400 million.

2 Jul 2013

University of Chicago Celiac Disease Center to host ICDS 2013

The University of Chicago Celiac Disease Center is hosting the 15th International Celiac Disease Symposium (ICDS) on Sept. 22-25, 2013 in Chicago. The symposium is the largest celiac disease and gluten-related disorders conference in the world.

2 Jul 2013

Fondation Leducq grants $6M to cardiovascular scientists to help advance cardiac regeneration therapeutics

The Fondation Leducq in Paris, France, dedicated to improving human health through international efforts to combat cardiovascular disease, awarded a $6 million grant award to a new global research network of cardiovascular scientists which includes three researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai.

2 Jul 2013

New mechanism triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes

Researchers at NYU Langone Medical Center have discovered a mechanism that triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes. The results, published today in Nature Immunology, suggest a common biochemical thread to multiple diseases and point the way to a new class of therapies that could treat chronic inflammation in these non-infectious diseases without crippling the immune system.

2 Jul 2013

Medicine News and Research

Activation of brown fat increases heart-related mortality during winter

Salsalate lowers blood glucose and improves glycemic control in T2D, say scientists

FDA-approved formoterol drug improves cognitive function in mouse model of Down syndrome

Researchers find NRF2 signaling plays a role in growth of tumor cells by altering metabolic pathways

Devon Medical gets ANVISA certification for extriCARE 2400 NPWT system

First Edition: July 2, 2013

Study finds that long-term cannabis use affects motivation

ARIAD Pharmaceuticals' Iclusig gets EC marketing authorization for CML and Ph+ ALL treatment

UCLA researchers introduce gene therapy technique to treat sickle cell disease

Nanofiber Solutions wins Ohio Third Frontier Technology Validation and Start-up Fund award

RLI awards scholarships to 10 residents to attend RLI Annual Event

Research roundup: 'Welcome-mat' effect of Medicaid expansion; Setting up shops; California's transition to Medicaid managed care

UH and Case Western Reserve University to develop diagnostic tests to determine HIV drug resistance

Osteoarthritis associated genes: an interview with Professor Jonathan Tobias, University of Bristol

Parents, children should leave fireworks displays to experts, say Vanderbilt specialists

FDA sends Complete Response Letter to Merck regarding investigational drug for insomnia

Lawmakers gird for new abortion fight as Texas special session convenes

University of Chicago Celiac Disease Center to host ICDS 2013

Fondation Leducq grants $6M to cardiovascular scientists to help advance cardiac regeneration therapeutics

New mechanism triggers chronic inflammation in Alzheimer's, atherosclerosis and type-2 diabetes

Everything there is to know about biosimilars eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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