Kidney News and Research

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Investigational drug abemaciclib shows durable clinical activity for variety of cancer types

The investigational anticancer therapeutic abemaciclib, which targets CDK4 and CDK6, showed durable clinical activity when given as continuous single-agent therapy to patients with a variety of cancer types, including breast cancer, non-small cell lung cancer (NSCLC), glioblastoma, and melanoma, according to results from a phase I clinical trial.

23 May 2016

Study: One-third of patients hospitalised with heart failure do not return to work

One-third of patients hospitalised with heart failure for the first time have not returned to work one year later, reveals a study in nearly 12 000 patients presented today at Heart Failure 2016 and the 3rd World Congress on Acute Heart Failure by Dr Rasmus Roerth, a physician at Copenhagen University Hospital in Copenhagen, Denmark.

23 May 2016

Intensive blood pressure lowering therapies can cut heart disease risk in older adults

Intensive therapies to reduce high blood pressure can cut the risk of heart disease in older adults without increasing the risk for falls, according to doctors at Wake Forest Baptist Medical Center.

21 May 2016

Study examines effects of ultra-low doses of glyphosate on gene expression profiles

Glyphosate, often sold under the brand name of Roundup, is the world's most widely used weed-killer. While Glyphosate has approval from regulatory bodies worldwide, there are growing concerns about its possible adverse health effects.

20 May 2016

SeeKD targeted screening program helps early detection of CKD risk in Canadians

A screening program for chronic kidney disease (CKD) initiated in Canada has successfully identified a high proportion of individuals with risk factors for CKD as well as many with unrecognized CKD.

20 May 2016

Combined public health intervention could help manage CKD in developing countries

A simple and inexpensive public health intervention helped prevent many cases of chronic kidney disease (CKD) in Pakistan. The intervention, which is described in a study in the Clinical Journal of the American Society of Nephrology, will be especially helpful for protecting the kidney health of people living in developing countries.

20 May 2016

Study finds that ACS NSQIP Surgical Risk Calculator has excellent calibration

The American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator accurately estimates the chance of a patient experiencing postoperative complications, and its performance can improve with recalibration of the tool according to research findings appearing online in the Journal of the American College of Surgeons in advance of print publication.

20 May 2016

Gene editing technology helps excise segment of HIV-1 DNA from genomes of living animals

Using gene editing technology, researchers at the Lewis Katz School of Medicine at Temple University have, for the first time, successfully excised a segment of HIV-1 DNA - the virus responsible for AIDS - from the genomes of living animals.

20 May 2016

Simple sarcopenia screening method could easily diagnose severity of heart disease

Researchers from Kumamoto University in Japan have shown that a simple screening method could quickly and easily diagnose the severity of heart disease. The method was originally developed to diagnose sarcopenia, a disease that causes a loss of muscle mass and strength.

19 May 2016

Innovative research technique may help understand early stage kidney disease

UT Dallas scientists are developing an innovative research technique that could help urologists better understand the early stages of kidney disease.

19 May 2016

New lab blood test may help identify HELLP syndrome in pregnant women

A laboratory blood test developed at Johns Hopkins for the diagnosis of a rare genetic red blood cell disorder also shows promise in identifying HELLP syndrome, a life-threatening high blood pressure condition affecting 1 percent of all pregnant women that causes hypertension along with end organ damage, researchers report in the May issue of the journal Experimental Hematology.

19 May 2016

UD scientists merge electronic health records to improve care, clinical outcomes for CKD patients

Electronic health records have the potential to reduce the incidence of medical errors, duplication of tests, and delays in treatment.

19 May 2016

Rural hospitals may work well for straightforward surgeries in relatively healthy patients

They may be in small towns. They may only have a couple of surgeons. But for common operations, they may be safer and less expensive than their larger cousins, a new study finds.

18 May 2016

Motor protein Myo1c uses actin cytoskeleton as 'track' for Neph1 transport

The motor protein Myo1c binds to Neph1, a protein crucial for ensuring effective filtration by the kidney, and serves as one mode of its cellular transport, according to findings by investigators at the Medical University of South Carolina and their collaborators reported in the May 16, 2016 issue of Molecular and Cellular Biology.

17 May 2016

Study shows inhibition of SHP-2 enzyme can diminish lupus symptoms

Researchers at Beth Israel Deaconess Medical Center have identified an enzyme that is significantly elevated in mouse models of systemic lupus erythematosus and in blood samples of patients with lupus.

17 May 2016

FDA approves additional indication for Eisai's anticancer agent Lenvima in combo with Everolimus for advanced renal cell carcinoma

Eisai Co., Ltd. has announced that its U.S. subsidiary Eisai Inc. has received approval from the U.S. Food and Drug Administration (FDA) for an additional indication for Eisai's in-house developed novel anticancer agent Lenvima (lenvatinib mesylate) in combination with everolimus for the treatment of patients with advanced renal cell carcinoma following one prior anti-angiogenic therapy.

16 May 2016

University of Colorado Boulder combines Raman spectroscopy and nanoindentation for improved materials characterisation

The University of Colorado Boulder, USA, combines Raman spectroscopy and nanoindentation for improved materials characterisation.

From Renishaw plc - Spectroscopy 16 May 2016

Neos announces U.S. launch of Adzenys XR-ODT for ADHD

Neos Therapeutics, Inc., a pharmaceutical company with a late‐stage pipeline of innovative extended-release (XR) product candidates for the treatment of attention-deficit/hyperactivity disorder (ADHD), today announced that Adzenys XR-ODT™ is in distribution channels and is now available to prescribe for patients with ADHD in the United States.

16 May 2016

Myocardial fibrosis linked to adverse cardiovascular outcomes in OSA patients

Myocardial fibrosis could be a future therapeutic target after researchers found it correlated with adverse cardiovascular outcomes in patients with obstructive sleep apnoea (OSA) referred for cardiac magnetic resonance (CMR).

13 May 2016

'Weekend effect’ may contribute to worsening availability of donor kidneys in the U.S

Investigators have uncovered a "weekend effect" contributing to the worsening availability of donor kidneys in the United States. They found that kidneys that would normally be made available for transplantation were less likely to be procured from donors over the weekend (89.5% on the weekend vs. 90.2% during the week).

13 May 2016

Kidney News and Research

Investigational drug abemaciclib shows durable clinical activity for variety of cancer types

Study: One-third of patients hospitalised with heart failure do not return to work

Intensive blood pressure lowering therapies can cut heart disease risk in older adults

Study examines effects of ultra-low doses of glyphosate on gene expression profiles

SeeKD targeted screening program helps early detection of CKD risk in Canadians

Combined public health intervention could help manage CKD in developing countries

Study finds that ACS NSQIP Surgical Risk Calculator has excellent calibration

Gene editing technology helps excise segment of HIV-1 DNA from genomes of living animals

Simple sarcopenia screening method could easily diagnose severity of heart disease

Innovative research technique may help understand early stage kidney disease

New lab blood test may help identify HELLP syndrome in pregnant women

UD scientists merge electronic health records to improve care, clinical outcomes for CKD patients

Rural hospitals may work well for straightforward surgeries in relatively healthy patients

Motor protein Myo1c uses actin cytoskeleton as 'track' for Neph1 transport

Study shows inhibition of SHP-2 enzyme can diminish lupus symptoms

FDA approves additional indication for Eisai's anticancer agent Lenvima in combo with Everolimus for advanced renal cell carcinoma

University of Colorado Boulder combines Raman spectroscopy and nanoindentation for improved materials characterisation

Neos announces U.S. launch of Adzenys XR-ODT for ADHD

Myocardial fibrosis linked to adverse cardiovascular outcomes in OSA patients

'Weekend effect’ may contribute to worsening availability of donor kidneys in the U.S

Free guide - Everything about renal proximal tubule cells eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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