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UCLA researchers receive $13 million NIH grant to combat melanoma

UCLA researchers have received a $13 million grant from the National Institutes of Health to find new ways to overcome melanoma resistance to some of the most promising targeted therapies and immunotherapies.

28 Sep 2020

Healthy vitamin D levels could reduce COVID-19 complications

Published in the journal PLOS ONE, the study investigates the link between serum 25-hydroxyvitamin D levels and its effect on adverse clinical outcomes and parameters of immune function and mortality due to COVID-19.

28 Sep 2020

New agreements to ensure all countries have fair access to COVID-19 rapid diagnostic tests

A set of agreements to make available, for low and middle-income countries, affordable, high-quality COVID-19 antigen rapid tests were today announced by the Access to COVID-19 Tools (ACT) Accelerator.

28 Sep 2020

Study pinpoints heating element in vaping devices as cause for lung injuries

Early results of an experimental vaping study have shown significant lung injury from E-cigarette (eC) devices with nickel-chromium alloy heating elements.

28 Sep 2020

J&J's COVID-19 vaccine shows potent immune response in phase 2 human trial

A multicenter phase 1/2a randomized, double-blinded, placebo-controlled clinical trial has been conducted recently to evaluate the safety, reactogenicity, and immunogenicity of a non-replicating adenovirus-based vaccine, namely Ad26.COV2.S against severe acute respiratory coronavirus 2 (SARS-CoV-2) infection.

28 Sep 2020

A new generation of microelectrode-array chips for recording nerve cell impulses

ETH researchers have developed a new generation of microelectrode-array chips for measuring nerve impulses, enabling studies of how thousands of nerve cells interact with each other.

28 Sep 2020

Stanford researchers unravel how a common genetic deletion elevates schizophrenia risk

A common genetic deletion boosts the risk for schizophrenia by 30-fold. Generating nerve cells from people with the deletion has showed Stanford researchers why.

28 Sep 2020

COVID-19 may deteriorate men's testosterone levels, new data suggests

For the first time, data from a study with patients hospitalized due to COVID-19 suggest that the disease might deteriorate men's testosterone levels.

28 Sep 2020

Evolutionary and heritable axes shape the organization of brain structure

Every region has its place in the brain. However, it has been unclear why brain regions are located where they are.

28 Sep 2020

Researchers discover specific cellular pathway involved in lung tissue regeneration

Researchers at Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania have identified a cellular pathway that can be targeted with a naturally occurring drug to stimulate lung tissue regeneration, which is necessary for recovery from multiple lung injuries.

28 Sep 2020

Science academies present joint statement on health, sustainability, and digitization

In the run-up to the summit of the G20 countries in November 2020 to be held in Riyadh (Saudi Arabia), the science academies of these countries have presented their joint statement "Foresight: Science for Navigating Critical Transitions".

28 Sep 2020

Genetic testing is cost-effective, beneficial for newly diagnosed patients with metastatic GIST

Because gastrointestinal stromal tumors (GIST) are sensitive to the targeted small molecule therapy imatinib, oncologists tend to treat all patients with metastatic GIST with this drug. However, because this rare type of cancer is caused by different genetic mutations, imatinib does not help all patients equally.

28 Sep 2020

Brain wiring genes may be linked to a significant portion of cerebral palsy cases

In an article published in Nature Genetics, researchers confirm that about 14% of all cases of cerebral palsy, a disabling brain disorder for which there are no cures, may be linked to a patient's genes and suggest that many of those genes control how brain circuits become wired during early development.

28 Sep 2020

Life-threatening COVID-19 associated with specific genetic variants

Results of a genome-wide association study on 2,244 critically-ill patients due to coronavirus disease (COVID-19) from 208 intensive care units across the United Kingdom revealed significant host-specific genetic determinants that can predispose people to the severe form of the disease. The report is currently available on the medRxiv preprint server.

28 Sep 2020

Blocking nuclear pore complex formation can help selectively kill cancer cells

Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that blocking the construction of nuclear pores complexes--large channels that control the flow of materials in and out of the cell nucleus--shrank aggressive tumors in mice while leaving healthy cells unharmed.

28 Sep 2020

Epigenetic changes in the brain drive late-onset Alzheimer's disease

New findings suggest that late-onset Alzheimer's Disease is driven by epigenetic changes -- how and when certain genes are turned on and off -- in the brain. Results were published today in Nature Genetics.

28 Sep 2020

Scientists identify a new way to regulate cell plasticity

Cell plasticity is a property by which a cell can take on different and reversible identities. Cell plasticity is also essential for embryo development and for the correct function of the immune system.

28 Sep 2020

New mechanism that prevents hair loss identified

A team of researchers from Cologne and Helsinki has discovered a mechanism that prevents hair loss: hair follicle stem cells, essential for hair to regrow, can prolong their life by switching their metabolic state in response to low oxygen concentration in the tissue.

28 Sep 2020

Researchers decipher how the immune system memorizes pathogens after an infection

The immune system will memorize the pathogen after an infection and can therefore react promptly after reinfection with the same pathogen. Now, scientists at the University of Würzburg have deciphered new details of this process.

28 Sep 2020

Study finds new treatment approach for patients with salt sensitive hypertension

High blood pressure (hypertension) affects one in two U.S. adults and can cause hardening and thickening of the arteries (atherosclerosis), which can lead to heart attacks, strokes or other complications including chronic kidney disease.

28 Sep 2020

Research News and Research

UCLA researchers receive $13 million NIH grant to combat melanoma

Healthy vitamin D levels could reduce COVID-19 complications

New agreements to ensure all countries have fair access to COVID-19 rapid diagnostic tests

Study pinpoints heating element in vaping devices as cause for lung injuries

J&J's COVID-19 vaccine shows potent immune response in phase 2 human trial

A new generation of microelectrode-array chips for recording nerve cell impulses

Stanford researchers unravel how a common genetic deletion elevates schizophrenia risk

COVID-19 may deteriorate men's testosterone levels, new data suggests

Evolutionary and heritable axes shape the organization of brain structure

Researchers discover specific cellular pathway involved in lung tissue regeneration

Science academies present joint statement on health, sustainability, and digitization

Genetic testing is cost-effective, beneficial for newly diagnosed patients with metastatic GIST

Brain wiring genes may be linked to a significant portion of cerebral palsy cases

Life-threatening COVID-19 associated with specific genetic variants

Blocking nuclear pore complex formation can help selectively kill cancer cells

Epigenetic changes in the brain drive late-onset Alzheimer's disease

Scientists identify a new way to regulate cell plasticity

New mechanism that prevents hair loss identified

Researchers decipher how the immune system memorizes pathogens after an infection

Study finds new treatment approach for patients with salt sensitive hypertension

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