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Researchers show how an important inhibitor binds to the A2A receptor

The A2A receptor regulates how vigorously the innate immune system attacks diseased cells.

25 Mar 2022

Shorter course of antibiotics associated with fewer antibiotic resistance genes

Antibiotic resistance is a growing problem worldwide that threatens the efficacy of available treatments and can lead to extended hospital stays and increased mortality.

24 Mar 2022

SARS-CoV-2 is evolving adaptively in multiple regions of the genome

Scientists from the United States have recently assessed the evolutionary success of mutations accumulated across severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome. They have observed that the positively-selected mutations in the viral spike S1 subunit are primarily responsible for adaptive evolution. This indicates that the virus may undergo antigenic drift.

23 Mar 2022

New therapy makes immunologically 'cold' tumors hot enough for immune attack

Pancreatic cancer is notoriously difficult to cure or even treat. Now, a new strategy devised by scientists at Albert Einstein College of Medicine has succeeded in making pancreatic tumors visible to the immune systems of mice and vulnerable to immune attack, reducing cancer metastases by 87%.

23 Mar 2022

Scientists develop first drug to treat uncontrolled secretion of mucins in the airways

A multicenter research team co-led by The University of Texas MD Anderson Cancer Center developed the first drug to treat the uncontrolled secretion of mucins in the airways, which causes potentially life-threatening symptoms in millions of Americans with asthma, chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF), as well as lung disease resulting from cancer and cancer treatment.

23 Mar 2022

Researchers investigate Galectin-9 as a new treatment target for COVID-19

Researchers discuss alternate therapeutic targets for treating COVID-19 and the effects of Gal-9 on SARS-CoV-2 infection and the immune response.

23 Mar 2022

UI neuroscientists identify fundamental biochemical mechanism underlying memory storage

A University of Iowa neuroscience research team has identified a fundamental biochemical mechanism underlying memory storage and has linked this mechanism to cognitive deficits in mouse models of Alzheimer's Disease and Related Dementias.

23 Mar 2022

People who consume sugar for extended periods have increased risk of autoimmune disease

People who consume sugar and other carbohydrates in excess over a long period of time have an increased risk of developing an autoimmune disease.

23 Mar 2022

Researchers find two gene variants linked to accelerated aging in childhood cancer survivors

Scientists from St. Jude Children's Research Hospital have identified variants in two genes that are associated with accelerated aging in childhood cancer survivors. Their research looked at the difference between their biological age and chronological age.

23 Mar 2022

Groundbreaking chemical technique could reveal new treatments for cancer and other diseases

Leicester researchers have described application of a pioneering chemical technique which could unlock ground-breaking new treatments for cancer and other diseases.

23 Mar 2022

Novel optobiological system may shine light on protein aggregation in Parkinson's disease

A novel system to control protein aggregation in a model of Parkinson's disease may answer longstanding questions about how the disease begins and spreads, according to a new study published March 9th in the open-access journal PLOS Biology by Abid Oueslati of Laval University, Quebec, Canada, and colleagues.

23 Mar 2022

WVU researcher unravels role of STAT5 protein in the development of multiple sclerosis

A human immune system is a lot like the board game Mouse Trap: it's a Rube Goldberg system of interacting parts. Only instead of a falling ball causing a tiny diver to leap into a tub - which, in turn, springs a trap on some plastic mice - proteins trigger other proteins to activate immune cells and direct them toward germs.

22 Mar 2022

The relative performance of OPS, NPS, and saliva for detecting the Delta and Omicron SARS-CoV-2 variants

Scientists have worked extensively hard to contain the COVID-19 pandemic caused by the rapid transmission of SARS-CoV-2.

22 Mar 2022

The effect of SARS-CoV-2 on the expression of CD48 in the lungs and in the peripheral blood of COVID-19 patients

Researchers performed an in situ analysis to evaluate the correlation between CD48 expression and COVID-19.

22 Mar 2022

Study evaluates interactions between SARS-CoV-2 proteins and viral and host RNA

A new study investigated the interactions between SARS-CoV-2 proteins and viral and host ribonucleic acid in virus-infected cells.

22 Mar 2022

Human parainfluenza type 3 virus outbreak in Seoul during SARS-CoV-2 pandemic

In a recent study posted to the bioRxiv* preprint server, researchers conducted a phylogenetic investigation of the human parainfluenza type 3 virus strain (HPIV3) that caused an outbreak in South Korea amid the coronavirus disease 2019 (COVID-19) pandemic.

22 Mar 2022

Experts highlight understated ethics, unclear utility of polygenic embryo testing

New technologies are expanding the reach and accessibility of preimplantation genetic testing of human embryos. But what these advances can deliver is still unclear, and a frank assessment of their profound ethical implications is urgently needed, concludes a commentary in Nature Medicine.

22 Mar 2022

Genes News and Research

Researchers show how an important inhibitor binds to the A2A receptor

Shorter course of antibiotics associated with fewer antibiotic resistance genes

SARS-CoV-2 is evolving adaptively in multiple regions of the genome

New therapy makes immunologically 'cold' tumors hot enough for immune attack

Scientists develop first drug to treat uncontrolled secretion of mucins in the airways

Researchers investigate Galectin-9 as a new treatment target for COVID-19

UI neuroscientists identify fundamental biochemical mechanism underlying memory storage

People who consume sugar for extended periods have increased risk of autoimmune disease

Researchers find two gene variants linked to accelerated aging in childhood cancer survivors

Groundbreaking chemical technique could reveal new treatments for cancer and other diseases

Novel optobiological system may shine light on protein aggregation in Parkinson's disease

WVU researcher unravels role of STAT5 protein in the development of multiple sclerosis

The relative performance of OPS, NPS, and saliva for detecting the Delta and Omicron SARS-CoV-2 variants

The effect of SARS-CoV-2 on the expression of CD48 in the lungs and in the peripheral blood of COVID-19 patients

Study evaluates interactions between SARS-CoV-2 proteins and viral and host RNA

Human parainfluenza type 3 virus outbreak in Seoul during SARS-CoV-2 pandemic

Experts highlight understated ethics, unclear utility of polygenic embryo testing

Study reveals novel tumor biomarker of aggressive cancers with poor prognosis

Is COVID-19 on the verge of ending?

Could COVID-19 spread through wastewater in the Thames?

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