B Cell News and Research

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Engineered virus-like particles power up gene editing, correcting blindness in mice

Prime editing, a versatile form of gene editing that can correct most known disease-causing genetic mutations, now has a new vehicle to deliver its machinery into cells in living animals.

8 Jan 2024

Growing tiny tumors in the lab for personalized lung cancer treatment

Lung cancer accounts for nearly 20% of annual cancer-related deaths worldwide. According to 2022 statistics from the Swiss Cancer League, nearly 5,000 new cases of lung cancer are reported in Switzerland each year.

8 Jan 2024

AI reveals hidden rules of cell neighborhoods in cancer

Researchers from Children's Hospital of Philadelphia have developed a new AI-powered algorithm to help understand how different cells organize themselves into particular tissues and communicate with one another.

8 Jan 2024

Gut microbiota: the new frontier in Alzheimer’s disease research and therapy

The current evidence of the role of gut microbiota in Alzheimer’s disease (AD) pathogenesis.

8 Jan 2024

Genetic keys to COVID-19 vaccine response unlocked

A genome-wide association study in the U.K. Biobank reveals genetic factors influencing IgG serostatus against SARS-CoV-2, highlighting the role of HLA class II genes in variable immune responses to COVID-19 vaccines.

7 Jan 2024

Sesame protein-derived peptides show promise in fighting E. coli and S. aureus

A study in "Nutrients" reveals that sesame protein-derived peptides, Ala-Gly-Gly-Val-Pro-Arg and Ser-Thr-Ile-Arg, show effective antibacterial activity against Escherichia coli and Staphylococcus aureus.

7 Jan 2024

Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy

Researchers at the University of Michigan Health Rogel Cancer Center have identified a mechanism that causes severe gastrointestinal problems with immune-based cancer treatment.

5 Jan 2024

Fruit fly research solves human disease and fuels new cancer immunotherapy approach

Scientists have solved a cellular murder mystery nearly 25 years after the case went cold. Following a trail of evidence from fruit flies to mice to humans revealed that cannibalistic cells likely cause a rare human immunodeficiency.

5 Jan 2024

Discovery on housekeeping genetic elements reveals a novel avenue in cancer therapy

Technological advancements have enabled scientists to comprehensively explore genetic control elements, unraveling the complexities of gene activation mechanisms in our genetic code.

5 Jan 2024

St. Jude scientists develop novel spectinomycin derivatives to combat Mycobacterium abscessus

Scientists at St. Jude Children's Research Hospital are tackling Mycobacterium abscessus (Mab) antibiotic resistance.

5 Jan 2024

Study reveals novel mechanism driving hypertension-induced arterial disease

A new study in Advanced Science unlocks the secrets of how high blood pressure (hypertension) fuels the progression of arterial disease.

5 Jan 2024

Stapled lipopeptides show promise as broad-spectrum antiviral agents

Compounds that obstruct the "landing gear" of a range of harmful viruses can successfully protect against infection by the virus that causes COVID-19, a study published today and led by Dana-Farber Cancer Institute scientists shows.

5 Jan 2024

IKAROS: Unlocking the secrets of the immune system's key player

In a scientific breakthrough that aids our understanding of the internal wiring of immune cells, researchers at Monash University in Australia have cracked the code behind IKAROS, an essential protein for immune cell development and protection against pathogens and cancer.

5 Jan 2024

Study identifies 9 novel genes linked to gestational diabetes

The largest genetic study of gestational diabetes to date has led to a discovery of nine novel genetic regions linked to this severe and common pregnancy complication.

5 Jan 2024

Breakthrough drug halts lung cancer and brain metastases

D'Or Institute for Research and Education (IDOR) played an important role in the phase III LIBRETTO-431 multicenter study, which evaluated the efficacy and safety of selpercatinib compared to control treatment, which consisted of platinum-based chemotherapy associated or not with pembrolizumab (immune checkpoint inhibitor) in non-small cell lung cancer (NSCLC).

5 Jan 2024

Epilepsy drug may alleviate joint degeneration associated with osteoarthritis

A new study in Nature described Nav1.7 as a key regulatory molecule in cartilage cells and reported the effectiveness of Nav1.7 blockade in reducing pain and slowing progression in OA.

5 Jan 2024

Unlocking the power of diet: How miRNAs influence health and disease

The role of dietary microRNAs (miRNAs) in health and disease.

5 Jan 2024

YAP and TAZ proteins guide bone development in the womb

A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."

4 Jan 2024

Study: Two-thirds of babies with sickle cell disease are born to mothers living in disadvantaged areas

As if starting life with a potentially disabling genetic blood disease wasn't enough, a study shows that almost two-thirds of babies born with sickle cell disease are born to mothers who live in disadvantaged areas.

4 Jan 2024

USC scientists develop first all-human brain organoids model of the cerebellum with functional neurons

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinje neurons.

4 Jan 2024

B Cell News and Research

Engineered virus-like particles power up gene editing, correcting blindness in mice

Growing tiny tumors in the lab for personalized lung cancer treatment

AI reveals hidden rules of cell neighborhoods in cancer

Gut microbiota: the new frontier in Alzheimer’s disease research and therapy

Genetic keys to COVID-19 vaccine response unlocked

Sesame protein-derived peptides show promise in fighting E. coli and S. aureus

Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy

Fruit fly research solves human disease and fuels new cancer immunotherapy approach

Discovery on housekeeping genetic elements reveals a novel avenue in cancer therapy

St. Jude scientists develop novel spectinomycin derivatives to combat Mycobacterium abscessus

Study reveals novel mechanism driving hypertension-induced arterial disease

Stapled lipopeptides show promise as broad-spectrum antiviral agents

IKAROS: Unlocking the secrets of the immune system's key player

Study identifies 9 novel genes linked to gestational diabetes

Breakthrough drug halts lung cancer and brain metastases

Epilepsy drug may alleviate joint degeneration associated with osteoarthritis

Unlocking the power of diet: How miRNAs influence health and disease

YAP and TAZ proteins guide bone development in the womb

Study: Two-thirds of babies with sickle cell disease are born to mothers living in disadvantaged areas

USC scientists develop first all-human brain organoids model of the cerebellum with functional neurons

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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