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Regulatory T cell populations descend from two different origins, finds study

A regulatory class of human T cells descends from two different origins, one that relates to autoimmunity and one that relates to protective immunity, according to a new study led by Children's Hospital of Philadelphia (CHOP).

7 Apr 2023

Newly discovered antibody appears to block infection by all dominant variants of SARS-CoV-2 virus

A team led by researchers at Weill Cornell Medicine, the University of Wisconsin-Madison; Scripps Research and the University of Chicago has identified an antibody that appears to block infection by all dominant variants of the virus that causes COVID-19, including Omicron, the most recent.

7 Apr 2023

3D structure of a probable precursor to the CRISPR-Cas12 enzyme revealed

Gene editing is one of the latest breakthroughs in biology. The widely known CRISPR-Cas gene editing system provided prokaryotes (organisms that lack cell nuclei) an immunity against foreign DNA. Since the discovery of the CRISPR gene editing technology, scientists are revealing the evolution of the CRISPR-Cas proteins from their precursors.

7 Apr 2023

Discovery may change the way people think about immune strategies

The human body is capable of creating a vast, diverse repertoire of antibodies - the Y-shaped sniffer dogs of the immune system that can find and flag foreign invaders.

7 Apr 2023

Highly complementary, biologically relevant protein-protein interactions can evolve entirely by chance

Proteins are the key players for virtually all molecular processes within the cell. To fulfil their diverse functions, they have to interact with other proteins.

7 Apr 2023

Study explores the association between gut microbiome dysbiosis and uveitis

Researchers provide an overview of existing research on the correlation between uveitis and gut dysbiosis.

7 Apr 2023

Mediterranean diet and the modulation of mitochondrial function

Researchers reviewed the current knowledge related to the Mediterranean diet (MedDiet) and the role of mitochondria concerning health outcomes.

7 Apr 2023

Is mRNA decoding in humans structurally and kinetically distinct from bacteria?

Researchers examined molecular-level differences in ribosomal translational fidelity between humans and bacteria.

7 Apr 2023

Broccoli intake protects the small intestine lining, inhibits development of disease

Broccoli is known to be beneficial to our health. For example, research has shown that increased consumption of the cruciferous vegetable decreases incidences of cancer and type 2 diabetes.

6 Apr 2023

Activation of adult-born neurons restores cognitive, affective function in Alzheimer’s mouse models

People with Alzheimer's disease develop defects in cognitive functions like memory as well as problems with noncognitive functions that can lead to anxiety and depression.

6 Apr 2023

Nasal SARS-CoV-2 vaccine outperforms existing vaccines in preclinical trial

Researchers assess the role of the live-attenuated vaccine sCPD9 in inducing systemic and mucosal immunity against SARS-CoV-2 variants.

6 Apr 2023

Pathophysiology, comorbidities, and interventions related to childhood obesity

Researchers discuss the psychological and physiological impacts of obesity on children.

6 Apr 2023

How nanomedicine is revolutionizing care for cardiovascular disease

Researchers review recent advancements in nanomedicine treatment options for cardiovascular disease.

6 Apr 2023

Phase 2 study shows safety and efficacy of new drug in men with high-risk prostate cancers

A new drug, a monoclonal antibody known as enoblituzumab, is safe in men with aggressive prostate cancer and may induce clinical activity against cancer throughout the body, according to a phase 2 study led by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Apr 2023

Combinatorial biomarker predicts response to immunotherapy in kidney cancer patients

The number of immune cells in and around kidney tumors, the amount of dead cancer tissue, and mutations to a tumor suppressor gene called PBRM1 form a biomarker signature that can predict — before treatment begins — how well patients with kidney cancer will respond to immunotherapy, according to new research directed by investigators at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy.

6 Apr 2023

Protein C News and Research

Regulatory T cell populations descend from two different origins, finds study

Newly discovered antibody appears to block infection by all dominant variants of SARS-CoV-2 virus

3D structure of a probable precursor to the CRISPR-Cas12 enzyme revealed

Discovery may change the way people think about immune strategies

Highly complementary, biologically relevant protein-protein interactions can evolve entirely by chance

Study explores the association between gut microbiome dysbiosis and uveitis

Mediterranean diet and the modulation of mitochondrial function

Is mRNA decoding in humans structurally and kinetically distinct from bacteria?

Broccoli intake protects the small intestine lining, inhibits development of disease

Activation of adult-born neurons restores cognitive, affective function in Alzheimer’s mouse models

Nasal SARS-CoV-2 vaccine outperforms existing vaccines in preclinical trial

Pathophysiology, comorbidities, and interventions related to childhood obesity

How nanomedicine is revolutionizing care for cardiovascular disease

Phase 2 study shows safety and efficacy of new drug in men with high-risk prostate cancers

Combinatorial biomarker predicts response to immunotherapy in kidney cancer patients

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

Study examines the causal role of insomnia symptoms on 11,409 health related-symptoms

Study reviews the diagnosis and treatment of acute myocarditis

Exploring the gut microbiome's role in rheumatoid arthritis pathogenesis

Study explores the species-specific use of ACE2 receptors by human and animal coronaviruses

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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