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Trastuzumab deruxtecan offers added benefit for patients with HER2-low breast cancer

The antibody-drug conjugate trastuzumab deruxtecan is approved for various therapeutic indications. Since March 2023, it can also be used as monotherapy for the treatment of adults with unresectable or metastatic HER2-low breast cancer who have received prior chemotherapy at this disease stage or developed disease recurrence early after adjuvant chemotherapy.

31 Oct 2023

Mechanical thrombectomy found to be effective for high-risk pulmonary embolism

New research from the FLASH registry (ClinicalTrials.gov identifier: NCT03761173) shines a light on the effectiveness of large-bore mechanical thrombectomy in managing high-risk pulmonary embolism.

31 Oct 2023

Sickle cell disease patients willing to accept high risks for gene therapy cure

Individuals living with severe sickle cell disease (SCD) are highly interested in new, potentially curative gene therapy treatments and are willing to accept associated risks for a chance at a cure, according to a study published today in Blood Advances.

31 Oct 2023

Using synthetic biology to develop smarter cell therapies for cancer patients

We are embarking on an unprecedented era of therapeutic development enabled by live cell engineering.

31 Oct 2023

Understanding COVID-19 mortality in people with severe mental illness and different ethnicities

In a recent study published in the British Journal of Psychiatry, researchers evaluated mortality in individuals with severe mental illness (SMI) following COVID-19.

31 Oct 2023

University of Melbourne students develop customized video game controller for kid with cerebral palsy

Jerome, a seven-year-old boy with cerebral palsy (CP), has been able to play a video game for the first time, with the help of a team of University of Melbourne Biomedical Engineering Masters students, who have co-designed a customised video game controller with him.

31 Oct 2023

UniSA seeks public support for vital research on deadly brain cancers

The University of South Australia is seeking public support for vital brain cancer research that could potentially save hundreds of lives.

31 Oct 2023

University of Cincinnati to lead NIH StrokeNet for next five years

The University of Cincinnati and UC Health have been renewed as the National Coordinating Center of the National Institutes of Health (NIH) StrokeNet, which is the primary infrastructure for multicenter trials of stroke funded by NIH and the pipeline for new potential treatments for adults and children with stroke and those at risk for stroke.

30 Oct 2023

Scientists identify mechanism of alcohol withdrawal headaches

About 283 million people worldwide suffer from alcohol use disorder, a debilitating health challenge for which limited therapeutic options are available. The cost to society is estimated at greater than $2 trillion annually.

30 Oct 2023

Canadian Cardiovascular Society releases new heart attack classification based on heart tissue damage

The Canadian Cardiovascular Society (CCS) released the world's first classification of acute myocardial infarction (AMI), or heart attack, based on heart tissue damage research that was driven by two cardiovascular investigators within the Ischemic Heart Disease Program of Krannert Cardiovascular Research Center (KCVRC) at Indiana University School of Medicine and Northern Ontario School of Medicine.

30 Oct 2023

Study unveils new approach to more precise, long-lasting, and less toxic cancer treatment

For too long, cancer treatment has been a double-edged sword – the very treatments designed to kill cancer cells often wrought havoc on healthy ones too.

30 Oct 2023

Updated toolkit to guide global menopause care

Care for women with menopausal health issues should improve globally following the release of an updated Monash University-led toolkit that guides health professionals around the world in assessing and treating them.

30 Oct 2023

Does adding sigh breaths to the usual care of trauma patients receiving mechanical ventilation increase ventilator-free days?

Researchers investigated whether adding sigh breaths to standard care regimens of mechanically ventilated trauma patients increased ventilator-free days.

30 Oct 2023

How does the Mediterranean diet impact insulin resistance and sensitivity in obese individuals?

Researchers evaluate the associations between adherence to the Mediterranean diet, insulin secretion, resistance, and sensitivity in obese individuals.

30 Oct 2023

Stopping metformin early linked to higher dementia risk in older adults with type 2 diabetes

Early termination of metformin treatment in older adults with type 2 diabetes is associated with a higher risk of dementia, according to a cohort study. The research has significant implications for diabetes management, especially among those at higher risk for dementia.

29 Oct 2023

Machine learning sheds light on mental health challenges faced by HCWs during COVID-19 pandemic

Machine learning reveals unique mental health struggles among healthcare workers during the COVID-19 pandemic, highlighting the urgent need for specialized support. The study analyzed therapy transcripts to show how healthcare professionals faced distinct challenges, including heightened anxiety and depression.

29 Oct 2023

New study highlights risks of anti-ERBB2 cancer drugs during pregnancy

Study finds that anti-ERBB2 inhibitors used in breast cancer treatment pose significant risks to pregnancy and fetal health, including higher likelihoods of congenital defects and intrauterine growth restriction. Researchers recommend careful monitoring and possibly discontinuing these drugs during pregnancy despite their effectiveness against cancer.

29 Oct 2023

MHRA grants conditional marketing authorization for AbbVie's Tepkinly to treat aggressive blood cancer

AbbVie today announced that the UK Medicines and Healthcare products Regulatory Agency has granted conditional Marketing Authorisation for Tepkinly® (epcoritamab) as a monotherapy for the treatment of adults with relapsed or refractory (R/R) diffuse large B-cell lymphoma (DLBCL), after two or more systemic therapies.

28 Oct 2023

Five ways AI can help to deal with the mental health crisis

Artificial intelligence is making waves in the world of health and beyond. And there are multiple ways that it can help people with their wellbeing and health, across mental and physical health.

28 Oct 2023

Study offers the most comprehensive look to date on prostate cancer disparities

Cedars-Sinai Cancer investigators have found that Black men respond as well as white men to systemic therapies for advanced prostate cancer when access to quality healthcare is equal, regardless of socioeconomic status.

27 Oct 2023

Therapy News and Research

Trastuzumab deruxtecan offers added benefit for patients with HER2-low breast cancer

Mechanical thrombectomy found to be effective for high-risk pulmonary embolism

Sickle cell disease patients willing to accept high risks for gene therapy cure

Using synthetic biology to develop smarter cell therapies for cancer patients

Understanding COVID-19 mortality in people with severe mental illness and different ethnicities

University of Melbourne students develop customized video game controller for kid with cerebral palsy

UniSA seeks public support for vital research on deadly brain cancers

University of Cincinnati to lead NIH StrokeNet for next five years

Scientists identify mechanism of alcohol withdrawal headaches

Canadian Cardiovascular Society releases new heart attack classification based on heart tissue damage

Study unveils new approach to more precise, long-lasting, and less toxic cancer treatment

Updated toolkit to guide global menopause care

Does adding sigh breaths to the usual care of trauma patients receiving mechanical ventilation increase ventilator-free days?

How does the Mediterranean diet impact insulin resistance and sensitivity in obese individuals?

Stopping metformin early linked to higher dementia risk in older adults with type 2 diabetes

Machine learning sheds light on mental health challenges faced by HCWs during COVID-19 pandemic

New study highlights risks of anti-ERBB2 cancer drugs during pregnancy

MHRA grants conditional marketing authorization for AbbVie's Tepkinly to treat aggressive blood cancer

Five ways AI can help to deal with the mental health crisis

Study offers the most comprehensive look to date on prostate cancer disparities

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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