Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

Secretome of pleural effusions linked to NSCLC and malignant mesothelioma

Cryopreserved cell-free PE fluid from 101 NSCLC patients, 8 mesothelioma and 13 with benign PE was assayed for a panel of 40 cytokines/chemokines using the Luminex system.

25 Nov 2019

Biosimilar for HER2+ breast cancer achieves similar overall response rate to reference drug

The trastuzumab biosimilar HLX02 achieved similar overall response rate to reference trastuzumab in women with human epidermal growth factor receptor 2-positive (HER2+) recurrent or previously untreated metastatic breast cancer, according to a large, randomized phase III study reported at the ESMO Asia 2019 Congress.

22 Nov 2019

Cochrane review provides information on HPV vaccines and dose schedules in young women, men

New evidence published in the Cochrane Library today provides further information on the benefits and harms of different human papillomavirus vaccines and vaccine schedules in young women and men.

22 Nov 2019

Experimental vaccine elicits antibodies that can neutralize multiple HIV strains

An experimental HIV vaccine developed by scientists at Scripps Research and the nonprofit vaccine research organization IAVI has reached an important milestone by eliciting antibodies that can neutralize a wide variety of HIV strains.

21 Nov 2019

Exploring the links between chronic stress, inflammation and depression

Chronic stress can inflame our brain, destroy the connections between our neurons and result in depression, scientists say.

21 Nov 2019

Applying a Proteomics-based Approach to the Clinic

Matthias Mann explains why applying proteomics-based technologies such as timsTOF could accelerate the diagnosis and prediction of human disease.

From Bruker Daltonics 20 Nov 2019

Malaria research advances immunotherapy in lupus, HIV

A new study published on November 19, 2019, in the journal Cell Reports, shows how the body’s immune system responds to malaria, which in turn promises to teach scientists how to design more effective therapies for a range of illnesses that are modulated by the immune response.

19 Nov 2019

Newly identified antibody has potential to stop, reverse pulmonary arterial hypertension

Scientists at the University of Sheffield, working in collaboration with drug and vaccine developer Kymab Ltd, Cambridge, have identified a novel antibody that has the potential to become a new treatment for pulmonary arterial hypertension (PAH).

15 Nov 2019

Study shows importance of targeted antibody treatment for patients with wet macular degeneration

Wet age-related macular degeneration is one of the leading causes of blindness in the U.S. Breakthrough treatments come with a steep price tag and treatment burden for the patient, but a new study suggests their benefits to patient health and society top billions of dollars, or more, if adherence could be improved.

15 Nov 2019

New treatment stops peanut allergy for 6 weeks with single dose

A small study published in the journal JCI Insight on November 14, 2019, suggests that antibody treatment could help people with severe allergy to peanuts eat a small amount of peanut-containing food just two weeks later, without any ill effects. This seems to show that this is a safe, fast and effective treatment for food allergy.

14 Nov 2019

Integral Molecular receives NIH contract for $5.5 million to advance vaccine discovery

The National Institute of Allergy and Infectious Diseases has awarded Integral Molecular a contract (75N93019C00073) which will provide up to $5.5M over the next five years to define antibody responses to pathogenic viruses including Zika, Marburg and equine encephalitis viruses, aiding the discovery of vaccines and therapeutics against these currently untreatable and often lethal viruses.

14 Nov 2019

Blocking metastasis-promoting enzyme can prevent spread of breast cancer

In a breakthrough with important implications for the future of immunotherapy for breast cancer, UC San Francisco scientists have found that blocking the activity of a single enzyme can prevent a common type of breast cancer from spreading to distant organs.

14 Nov 2019

Lonza launches new basal and feed medium to optimize protein production

Lonza has further expanded its cell culture media portfolio with the addition of the eCHO Basal Medium and Feed, which has been designed to optimize protein production by delivering a consistent yield and highly viable cells while keeping lactate levels to a minimum for optimal protein integrity.

From Lonza 14 Nov 2019

Researchers find mechanism that controls the growth of B1-cells

Directly after birth, the immune system completes production of a subtype of antibody-producing immune cells, B-1, that are to last for a lifetime. No more B1-cells are formed after that point. However, these cells are self-reactive - they produce not only antibodies against foreign substances, but also against the body's own substances, and it is unclear why the immune system allows for the development of these particular cells.

13 Nov 2019

Researchers take major step towards developing a viable vaccine for malaria

Researchers have narrowed down the malaria proteins and disease-fighting antibodies that could be used to develop a vaccine against the most severe forms of malaria.

13 Nov 2019

Scientists move closer towards developing an effective malaria vaccine

Scientists have taken another big step forward towards developing a vaccine that’s effective against the most severe forms of malaria.

13 Nov 2019

Russian scientists explain how an additional component can triple vaccine efficiency

A team of Russian scientists carried out a study on the cell immunity level and found out how an adjuvant called azoximer bromide increases the immunogenicity of the anti-flu vaccine.

12 Nov 2019

Autoimmune attack on uninfected red blood cells may cause anemia in malaria patients

An autoimmune attack on uninfected red blood cells likely contributes to anaemia - a shortage of red blood cells - in people with malaria, according to a new study published in eLife.

12 Nov 2019

Drug regimen for lymphoma and RA more likely to put patients with pemphigus into remission

Pemphigus, an autoimmune disease mediated by B cells and which causes painful blisters and sores on the skin and mucous membranes, is a rare chronic autoimmune condition that can be fatal if not treated.

11 Nov 2019

Lupus flare-ups could be linked to environmental factors

Researchers have found that alteration in the environment and atomospheric factors could be associated with organ specific flare-ups of lupus among patients diagnosed with Systemic Lupus Erethematosus (SLE). The study results were presented at the 2019 ACR/ARP Annual Meeting. The abstract was titled, “Environmental and Atmospheric Factors in Systemic Lupus Erythematosus: A Regression Analysis.”

11 Nov 2019

Antibody News and Research

Further Reading

Secretome of pleural effusions linked to NSCLC and malignant mesothelioma

Biosimilar for HER2+ breast cancer achieves similar overall response rate to reference drug

Cochrane review provides information on HPV vaccines and dose schedules in young women, men

Experimental vaccine elicits antibodies that can neutralize multiple HIV strains

Exploring the links between chronic stress, inflammation and depression

Applying a Proteomics-based Approach to the Clinic

Malaria research advances immunotherapy in lupus, HIV

Newly identified antibody has potential to stop, reverse pulmonary arterial hypertension

Study shows importance of targeted antibody treatment for patients with wet macular degeneration

New treatment stops peanut allergy for 6 weeks with single dose

Integral Molecular receives NIH contract for $5.5 million to advance vaccine discovery

Blocking metastasis-promoting enzyme can prevent spread of breast cancer

Lonza launches new basal and feed medium to optimize protein production

Researchers find mechanism that controls the growth of B1-cells

Researchers take major step towards developing a viable vaccine for malaria

Scientists move closer towards developing an effective malaria vaccine

Russian scientists explain how an additional component can triple vaccine efficiency

Autoimmune attack on uninfected red blood cells may cause anemia in malaria patients

Drug regimen for lymphoma and RA more likely to put patients with pemphigus into remission

Lupus flare-ups could be linked to environmental factors

Event guide: Targeted Therapies Partnering & Licensing Summit Asia eBook

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