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Maple leaf extract could prevent wrinkles

Maple trees are associated with the maple syrup that they provide. Researchers have now found that the trees could provide us with more. The extract from maple leaves can actually prevent wrinkles, they found.

20 Aug 2018

New drug shows potential to prevent painful side effect of therapy

About 50,000 people in the U.S. are diagnosed annually with head, neck, nasal and oral cancers. Most are treated with radiation, and of those, 70-80 percent develop a painful and debilitating side effect called severe oral mucositis.

20 Aug 2018

New integrated gene logic-chips could have great value in medical care

Gene expression is a fundamental of life, where each cell switches on and off specific genes. Thus, an autonomous device that could control the on-off switching would have great value in medical care.

20 Aug 2018

Dartmouth scientists create more sustainable feed for aquaculture

Dartmouth scientists have created a more sustainable feed for aquaculture by using a marine microalga co-product as a feed ingredient.

18 Aug 2018

Female mosquitoes quickly evolve selective mating behavior when faced with threats

Certain female mosquitoes quickly evolve more selective mating behavior when faced with existential threats from other invasive mosquito species, with concurrent changes to certain genetic regions, according to new research from North Carolina State University.

17 Aug 2018

Brief exposures to stressors can be beneficial to cells, shows study

We've all heard the expression: "what doesn't kill you makes you stronger." Now, research led by a Salk Institute scientist suggests why, at a cellular level, this might be true.

17 Aug 2018

Trial shows PARP inhibitor as novel treatment option for patients with advanced breast cancers

In a randomized, Phase III trial led by researchers at The University of Texas MD Anderson Cancer Center, the PARP inhibitor talazoparib extended progression-free survival (PFS) and improved quality-of-life measures over available chemotherapies for patients with metastatic HER2-negative breast cancer and mutations in the BRCA1/2 genes.

16 Aug 2018

New discoveries show how protein droplets do more than keep cells’ interiors tidy

Inside cells, where DNA is packed tightly in the nucleus and rigid proteins keep intricate transport systems on track, some molecules have a simpler way of establishing order. They can self-organize, find one another in crowded spaces, and quickly coalesce into droplets - like oil in water.

15 Aug 2018

Study reveals role of RUNX proteins in DNA repair

A study by researchers from the Cancer Science Institute of Singapore at the National University of Singapore has revealed that RUNX proteins are integral to efficient DNA repair via the Fanconi Anemia pathway.

15 Aug 2018

Ablating the mutant p53 gene in mice with colorectal cancer inhibits tumor growth

By genetically manipulating and removing the most common mutant form of the p53 gene that promotes colorectal cancer in humans, an international team of scientists demonstrated that this therapy reduces tumor growth and tissue invasion.

15 Aug 2018

Researchers discover new promising target point for cancer and diabetes therapies

If certain signaling cascades are misregulated, diseases like cancer, obesity and diabetes may occur. A mechanism recently discovered by scientists at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie in Berlin and at the University of Geneva has a crucial influence on such signaling cascades and may be an important key for the future development of therapies against these diseases.

15 Aug 2018

Scripps Research scientists uncover new approach for treating thrombocytopenia

Blood platelets are like the sand bags of the body. Got a cut? Platelets pile in to clog the hole and stop the bleeding.

15 Aug 2018

Clinical study suggests new treatment direction for head and neck cancer in heavy smokers

Patients with a greater than 10 pack/year history of smoking tend to develop an especially dangerous form of head and neck squamous cell cancer for which prognosis remains poor and treatments have changed little during the past two decades.

14 Aug 2018

OncoThira and NDSU enter into license agreement to develop, market cancer compounds

The NDSU Research Foundation and OncoThira have entered into a license agreement involving technology developed at North Dakota State University.

14 Aug 2018

Scientists discover key vulnerability of mixed lineage leukemia

Childhood leukemia is a diagnosis that no family ever wants to endure. While the treatment of most types of leukemia has improved steadily over the years, a few specific types remain very difficult to treat.

13 Aug 2018

FDA approves first oral medication for treatment of adults with Fabry disease

The U.S. Food and Drug Administration today approved Galafold (migalastat), the first oral medication for the treatment of adults with Fabry disease.

10 Aug 2018

Using CRISPR-Cas9 genome editing to correct mutation responsible for sickle cell disease

Genome editing using the CRISPR-Cas9 system has tremendous promise for therapeutic correction of genetic errors in human cells. Prior to adoption as a medical therapeutic, safety concerns relating to off-target effects must be minimized to mitigate risks that may arise from the unintended action of this system at sites similar, but not identical, to the desired gene target site.

From Integrated DNA Technologies 10 Aug 2018

Study provides snapshot of mechanism behind cancer metastasis for the first time

Metastasis, or the formation of secondary tumors, is a leading contributor to the vast majority of deaths related to cancer.

9 Aug 2018

Scientists identify key neurobiological mechanisms that control aggression

A number of psychiatric disorders present with aggression and violence, which, needless to say, are destructive to both individuals and societies worldwide: death, disease, disability, and numerous socioeconomic problems can often be traced back to aggressive behavior.

9 Aug 2018

Combination of arsenic and existing leukemia drug may combat cancer

Investigators have discovered that arsenic in combination with an existing leukemia drug work together to target a master cancer regulator.

9 Aug 2018

Enzyme News and Research

Maple leaf extract could prevent wrinkles

New drug shows potential to prevent painful side effect of therapy

New integrated gene logic-chips could have great value in medical care

Dartmouth scientists create more sustainable feed for aquaculture

Female mosquitoes quickly evolve selective mating behavior when faced with threats

Brief exposures to stressors can be beneficial to cells, shows study

Trial shows PARP inhibitor as novel treatment option for patients with advanced breast cancers

New discoveries show how protein droplets do more than keep cells’ interiors tidy

Study reveals role of RUNX proteins in DNA repair

Ablating the mutant p53 gene in mice with colorectal cancer inhibits tumor growth

Researchers discover new promising target point for cancer and diabetes therapies

Scripps Research scientists uncover new approach for treating thrombocytopenia

Clinical study suggests new treatment direction for head and neck cancer in heavy smokers

OncoThira and NDSU enter into license agreement to develop, market cancer compounds

Scientists discover key vulnerability of mixed lineage leukemia

FDA approves first oral medication for treatment of adults with Fabry disease

Using CRISPR-Cas9 genome editing to correct mutation responsible for sickle cell disease

Study provides snapshot of mechanism behind cancer metastasis for the first time

Scientists identify key neurobiological mechanisms that control aggression

Combination of arsenic and existing leukemia drug may combat cancer

Biochemical Assays for Efficient Hit Prioritization After Screening eBook

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