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Large survey of genetic variation offers insights into human diseases

A large survey of human genetic variation, published today in the online version of the journal Science, shows that rare genetic variants are not so rare after all and offers insights into human diseases.

19 May 2012

Rare DNA variations may be responsible for differences in susceptibility to common disorders

One-letter switches in the DNA code occur much more frequently in human genomes than anticipated, but are often only found in one or a few individuals. The abundance of rare variations across the human genome is consistent with the population explosion of the past few thousand years, medical geneticists and evolutionary biologists report in the May 17 advanced online edition of Science.

19 May 2012

Migraine is a neurological, not vascular, disorder

The latest genetic and biological research shows that migraine is a neurological, not vascular, disorder and both acute and preventive treatments being developed target peripheral and central nervous systems, according to a prominent migraine expert addressing the American Pain Society (APS)today.

18 May 2012

Ultrasensitive biosensor may open up new opportunities for early detection of cancer

Researchers have created an ultrasensitive biosensor that could open up new opportunities for early detection of cancer and "personalized medicine" tailored to the specific biochemistry of individual patients.

16 May 2012

Genetic test can accurately predict spread of eye cancer

Researchers at Washington University School of Medicine in St. Louis have developed a genetic test that can accurately predict whether the most common form of eye cancer will spread to other parts of the body, particularly the liver.

15 May 2012

Cubist announces results from CB-5945 Phase 2 studies on chronic non-cancer pain, OIC

Cubist Pharmaceuticals, Inc. today announced that the results from the Phase 2 studies of CB-5945 (formerly ADL5945) in patients with chronic non-cancer pain and opioid-induced constipation (OIC) will be presented at the 31st Annual Scientific Meeting of the American Pain Society taking place May 16 to 19, 2012, in Honolulu and during Digestive Disease Week 2012 taking place May 19 to 22, 2012, in San Diego.

15 May 2012

Study demonstrates accuracy of AliveCor’s iPhone-based ECG

AliveCor, the developer of a breakthrough mobile electrocardiogram (ECG) recorder, today announced results from a study that demonstrated the accuracy of the company's iPhone-based device, by comparing its Lead I to Lead I from a conventional 12-lead ECG. The study found that the iPhone-based event recorder is an accurate clinical tool for ECG assessment and could prove to be a new tool for allowing immediate recording and analysis of an ECG rhythm.

From AliveCor, Inc. 14 May 2012

Dyax introduces free Attack Tracker smartphone application for hereditary angioedema patients

Dyax Corp. today announced the launch of a free smartphone application for the iPhone - HAE Attack Tracker. This application allows HAE patients to keep detailed records of their disease related information, including emergency and physician contacts as well as individual attack data.

11 May 2012

African Americans have more severe complications from scleroderma

African Americans have more severe complications from systemic sclerosis, also known as scleroderma, than Caucasians. Findings published today in, Arthritis & Rheumatism, a journal of the American College of Rheumatology (ACR), show that compared with Caucasians, African-American patients were more likely to have antibodies that increased frequency and severity of pulmonary fibrosis, which is associated with decreased survival.

10 May 2012

Truvada deemed safe & effective in HIV infection risk reduction

Gilead Sciences Inc's Truvada pills are deemed safe and effective for reducing the risk of HIV infection, U.S. regulators said on Tuesday. But they recommended a cautious approach for using the drug in efforts to prevent the virus that causes AIDS.

9 May 2012

Grade 12 researcher wins top honors at 2012 Sanofi BioGENEius Challenge Canada

An Ontario girl, 16, who invented a disease-fighting, anti-aging compound using nano-particles from trees, won top national honours today in the 2012 Sanofi BioGENEius Challenge Canada.

9 May 2012

Highlights of orthopaedic research studies in JBJS

Below are highlights of orthopaedic research studies appearing in the May 2, 2012 issue of the Journal of Bone and Joint Surgery (JBJS), as well as the issue's full Table of Contents.

9 May 2012

DFG to establish seven new research units

The establishment of six new Research Units and one Clinical Research Unit has been decided by the Joint Committee of the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation). These networks will offer researchers the opportunity to address current and pressing issues in their fields and to pioneer innovative approaches. As all DFG Research Units, the new groups will work across locations and disciplines. Clinical Research Units combine clinical, applied and basic research.

8 May 2012

ProAssurance reports operating income of $48M for first quarter 2012

ProAssurance Corporation reports Operating Income of $48 million, or $1.56 per diluted share for the first quarter of 2012.

8 May 2012

Everett Labs announces availability of Pregnitude for women with fertility problems

A new non-prescription Reproductive Support Dietary Supplement, Pregnitude, which contains myo-inositol (2 g), plus folic acid (200 mcg), is now available for women who are having difficulty conceiving, Everett Laboratories announced today. In clinical studies, Pregnitude has been shown to help support ovulation function and menstrual cycle regularity as well as support the quality of a woman's eggs.

8 May 2012

Drug-related morbidity perceived to affect half of all patients attending healthcare

It is well known that drug-related morbidity is common among hospitalized patients, and is to some extent preventable, but less is known about drug-related morbidity outside hospitals. Two new studies conducted at the Nordic School of Public Health NHV, show that healthcare professionals perceive drug-related morbidity to affect half of all patients attending healthcare.

7 May 2012

CNV in prostate cancer tumors may accurately predict relapse

While active monitoring of serum prostate specific antigen (PSA) levels in men over 50 has greatly improved early detection of prostate cancer, prediction of clinical outcomes after diagnosis remains a major challenge.

7 May 2012

Screening for diabetic retinopathy once every two years maybe safe, cost-effective

Research carried out at the Peninsula College of Medicine and Dentistry (PCMD), University of Exeter, has concluded that it would be a safe and cost-effective strategy to screen people with type 2 diabetes who have not yet developed diabetic retinopathy, for the disease once every two years instead of annually.

7 May 2012

Researchers identify new mechanism that causes choroidal neovascularization

Sloppy shipping of a donated human retina to an Indiana University researcher studying a leading cause of vision loss has inadvertently helped uncover a previously undetected mechanism causing the disease. The discovery has led researchers to urge review of how millions of dollars are spent investigating the cause of a type of age-related macular degeneration called choroidal neovascularization.

5 May 2012

New light on many biological differences between individual breast cancers

New findings presented at Europe's leading breast cancer translational research conference this year shed new light on the many biological differences between individual breast cancers.

4 May 2012

Frequency News and Research

Large survey of genetic variation offers insights into human diseases

Rare DNA variations may be responsible for differences in susceptibility to common disorders

Migraine is a neurological, not vascular, disorder

Ultrasensitive biosensor may open up new opportunities for early detection of cancer

Genetic test can accurately predict spread of eye cancer

Cubist announces results from CB-5945 Phase 2 studies on chronic non-cancer pain, OIC

Study demonstrates accuracy of AliveCor’s iPhone-based ECG

Dyax introduces free Attack Tracker smartphone application for hereditary angioedema patients

African Americans have more severe complications from scleroderma

Truvada deemed safe & effective in HIV infection risk reduction

Grade 12 researcher wins top honors at 2012 Sanofi BioGENEius Challenge Canada

Highlights of orthopaedic research studies in JBJS

DFG to establish seven new research units

ProAssurance reports operating income of $48M for first quarter 2012

Everett Labs announces availability of Pregnitude for women with fertility problems

Drug-related morbidity perceived to affect half of all patients attending healthcare

CNV in prostate cancer tumors may accurately predict relapse

Screening for diabetic retinopathy once every two years maybe safe, cost-effective

Researchers identify new mechanism that causes choroidal neovascularization

New light on many biological differences between individual breast cancers

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From Discovery Biology to ELRIG Chair

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