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New sensor allows scientists to measure cancer cell's response to chemotherapy drug

MIT chemical engineers have developed a new sensor that lets them see inside cancer cells and determine whether the cells are responding to a particular type of chemotherapy drug.

8 Aug 2018

Study: Potential new class of drugs may lower heart disease risk by targeting gut microbes

Cleveland Clinic researchers have designed a potential new class of drugs that may reduce cardiovascular risk by targeting a specific microbial pathway in the gut.

7 Aug 2018

Inhibition of NOVA1 gene helps prevent growth of lung cancer tumors

Researchers have identified a gene that when inhibited or reduced, in turn, reduced or prevented human non-small cell lung cancer tumors from growing.

7 Aug 2018

Study: HDAC1 enzyme modifies molecular motor that drives neuron death

A biochemistry instructor curious about an enzyme discovered in the damaged neurons of people with multiple sclerosis made a leap toward a potential cure for countless neurodegenerative ills.

7 Aug 2018

Red blood cells contribute to cardiovascular diseases in patients with type 2 diabetes

Harmful effects of substances secreted from red blood cells could explain the increased risk of cardiovascular diseases in patients with type 2 diabetes, the results of two new studies conducted at Karolinska Institutet in Sweden indicate.

6 Aug 2018

Consuming crickets can help support growth of beneficial gut bacteria, clinical trial shows

Valerie Stull was 12 when she ate her first insect. "I was on a trip with my parents in Central America and we were served fried ants," she says. "I remember being so grossed out initially, but when I put the ant in my mouth, I was really surprised because it tasted like food -- and it was good!"

3 Aug 2018

EMA grants orphan designation to selumetinib for treatment of neurofibromatosis type 1

AstraZeneca and Merck, known as MSD outside the U.S. and Canada, today announced that the European Medicines Agency (EMA) has granted orphan designation to selumetinib, a MEK 1/2 inhibitor, for the treatment of neurofibromatosis type 1 (NF1).

3 Aug 2018

New nuclear medicine test could improve care of patients with type 1 diabetes

Researchers have discovered a new nuclear medicine test that could improve care of patients with type 1 diabetes. The new positron emission tomography imaging method could measure beta-cell mass, which would greatly enhance the ability to monitor and guide diabetes therapies.

3 Aug 2018

Regenacy Pharmaceuticals partners with CMTA to advance ricolinostat for treating hereditary neuropathy

Regenacy Pharmaceuticals, LLC, a clinical-stage biopharmaceutical company developing breakthrough treatments for diabetic and other peripheral neuropathies, today announced a collaboration with the Charcot-Marie-Tooth Association, a registered non-profit organization serving the hereditary neuropathy patient community, to validate the role of HDAC6 in multiple forms of Charcot-Marie-Tooth disease and evaluate the efficacy of ricolinostat, a selective HDAC6 inhibitor, in animal models.

2 Aug 2018

Rutgers researcher receives $100,000 grant to explore T-cell acute lymphoblastic leukemia

A one-year, $100,000 grant awarded to Rutgers Cancer Institute of New Jersey resident researcher Daniel Herranz Benito, PhD, will support exploration into an aggressive blood cancer that impacts both children and adults – T-cell acute lymphoblastic leukemia.

2 Aug 2018

Innovative 'EvolvR' system lets scientists shuffle genes until they get right variation

Scientists at the Innovative Genomics Institute have concocted a transformative new way to harness the power of evolution.

2 Aug 2018

New probe allows identification of cancer stem cells in situ

A fluorescent molecular probe that targets cancer stem cells has been developed at the University of Illinois at Urbana-Champaign.

2 Aug 2018

Tests show Drexel's polymer crystal nanocapsules can last longer in bloodstream

Selecting the right packaging to get precious cargo from point A to point B can be a daunting task at the post office. For some time, scientists have wrestled with a similar set of questions when packaging medicine for delivery in the bloodstream:

1 Aug 2018

New AI approach can teach itself to design new drug molecules from scratch

An artificial-intelligence approach created at the University of North Carolina at Chapel Hill Eshelman School of Pharmacy can teach itself to design new drug molecules from scratch and has the potential to dramatically accelerate the design of new drug candidates.

1 Aug 2018

Catalytic nanoparticles can effectively prevent tooth decay

Combine a diet high in sugar with poor oral hygiene habits and dental cavities, or caries, will likely result.

1 Aug 2018

New discovery may lead to targeted treatment for copper metabolism disorders

Individuals with defects in copper metabolism may soon have more targeted treatment options thanks to a discovery by a research team led by Dr. Vishal Gohil of Texas A&M AgriLife Research in College Station.

31 Jul 2018

Scientists find people's assumptions about DNA repair after CRISPR editing to be wrong

Despite high hopes and high investment in CRISPR-Cas9 gene editing, scientists still have a lot to learn about how it works in humans.

31 Jul 2018

Ivosidenib receives FDA approval to treat acute myeloid leukemia patients with IDH1 mutation

Clinical trials at University of Colorado Cancer Center and elsewhere now result in the drug ivosidenib earning approval from the U.S. Food and Drug Administration for the treatment of adult patients with relapsed or refractory acute myeloid leukemia with a susceptible isocitrate dehydrogenase-1 mutation.

30 Jul 2018

Pungent compound contained in ginger ensures fresh breath

The pungent compound 6-gingerol, a constituent of ginger, stimulates an enzyme contained in saliva - an enzyme which breaks down foul-smelling substances.

30 Jul 2018

Discovery opens up new ways to tackle growing threat of untreatable gonorrhea

Good news in the battle against the growing threat of drug-resistant “super gonorrhea”: Researchers at the University of Virginia School of Medicine and their collaborators in the United Kingdom have discovered a new way that the bacteria that cause gonorrhea resist the body’s immune defenses.

27 Jul 2018

Enzyme News and Research

New sensor allows scientists to measure cancer cell's response to chemotherapy drug

Study: Potential new class of drugs may lower heart disease risk by targeting gut microbes

Inhibition of NOVA1 gene helps prevent growth of lung cancer tumors

Study: HDAC1 enzyme modifies molecular motor that drives neuron death

Red blood cells contribute to cardiovascular diseases in patients with type 2 diabetes

Consuming crickets can help support growth of beneficial gut bacteria, clinical trial shows

EMA grants orphan designation to selumetinib for treatment of neurofibromatosis type 1

New nuclear medicine test could improve care of patients with type 1 diabetes

Regenacy Pharmaceuticals partners with CMTA to advance ricolinostat for treating hereditary neuropathy

Rutgers researcher receives $100,000 grant to explore T-cell acute lymphoblastic leukemia

Innovative 'EvolvR' system lets scientists shuffle genes until they get right variation

New probe allows identification of cancer stem cells in situ

Tests show Drexel's polymer crystal nanocapsules can last longer in bloodstream

New AI approach can teach itself to design new drug molecules from scratch

Catalytic nanoparticles can effectively prevent tooth decay

New discovery may lead to targeted treatment for copper metabolism disorders

Scientists find people's assumptions about DNA repair after CRISPR editing to be wrong

Ivosidenib receives FDA approval to treat acute myeloid leukemia patients with IDH1 mutation

Pungent compound contained in ginger ensures fresh breath

Discovery opens up new ways to tackle growing threat of untreatable gonorrhea

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