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Study: Mutated ATRX gene may serve as much-needed biomarker for rare neuroendocrine tumors

A somatic mutation in the ATRX gene has recently been shown as a potential molecular marker for aggressive brain tumors, such as gliomas, neuroblastomas and pancreatic neuroendocrine tumors. Now, for the first time, researchers at Penn's Abramson Cancer Center have found that the same mutated gene may serve as a much-needed biomarker for the pheochromocytomas and paragangliomas (PCC/PGL) that become malignant.

21 Jan 2015

Exposure to alcohol TV ads associated with underage drinking

Seeing and liking alcohol advertising on television among underage youths was associated with the onset of drinking, binge drinking and hazardous drinking, according to a study by researchers at the Norris Cotton Cancer Center and Children's Hospital at Dartmouth-Hitchcock published online by JAMA Pediatrics.

21 Jan 2015

MET amplified in NSCLC irrespective of type, genetic background

A third of non-small-cell lung cancers show low- to high-level amplification of the MET gene, according to a German study, with no significant difference in frequency across different types of cancer and genetic backgrounds.

20 Jan 2015

Effective vaccine booster schedules needed to fight against whooping cough resurgence

A key to victory in battle, according to Chinese general and military strategist Sun Tzu, is to know your enemy. In the current fight against whooping cough resurgence, perhaps the biggest obstacle is an incomplete understanding of its underlying causes, according to a University of Michigan population ecologist.

20 Jan 2015

Researchers turn clinical experience in multiple myeloma treatment into instructive review for physicians

Multiple myeloma is a malignant disease characterised by proliferation of clonal plasma cells in the bone marrow and typically accompanied by the secretion of monoclonal immunoglobulins that are detectable in the serum or urine. Increased understanding of the microenvironmental interactions between malignant plasma cells and the bone marrow niche, and their role in disease progression and acquisition of therapy resistance, has helped the development of novel therapeutic drugs for use in combination with cytostatic therapy.

20 Jan 2015

Scientists identify first genetic marker linked to severe neurological toxicity

Paclitaxel is a chemotherapeutic drug that has been shown to be highly effective when treating solid tumours, such as breast, ovarian and lung tumours. However, its use frequently causes peripheral neuropathies, neurological problems that affect the vast majority of patients.

15 Jan 2015

Researchers develop novel method to predict risk of liver cancer recurrence after transplantation

UCLA transplantation researchers have developed a novel method that more accurately calculates the risk of disease recurrence in liver cancer patients who have undergone a liver transplant, providing a new tool to help physicians make treatment and surveillance decisions.

14 Jan 2015

eAgile releases new UHF EPC compliant MicroWing inlay

eAgile Inc., a global leader in radio frequency identification (RFID) technologies, announced today the release of their new UHF EPC compliant MicroWing inlay. The MicroWing is the size of a paper clip which makes it the smallest RFID inlay available on the market to achieve a greater than 2 meter read range.

13 Jan 2015

EGFR mutations, ALK translocations not mutually exclusive in NSCLC

Researchers from the Republic of Korea have found that epidermal growth factor receptor mutations and anaplastic lymphoma kinase translocations can occur concomitantly in a proportion of patients with non-small-cell lung cancer.

12 Jan 2015

Survey shows radiation oncologists desire for more formal guidance to improve peer review process

Peer review is a common practice in medicine to support the complementary, multidisciplinary team approach in healthcare. A 2013 survey of radiation oncologists indicates that they would like more formal recommendations and guidance in order to improve the peer review process, according to a study published in the January-February 2015 issue of Practical Radiation Oncology, the clinical practice journal of the American Society for Radiation Oncology.

8 Jan 2015

Capsule Tech announces availability of healthcare's first medical device information system

Capsule Tech, Inc., the leading global provider of medical device integration solutions, recently announced the general availability of SmartLinx, healthcare's first medical device information system (MDIS).

7 Jan 2015

Study finds unnecessary hysterectomy in 1 out of 5 cases

It is estimated that one in three women in the United States will have had a hysterectomy by the age of 60. Although the numbers of hysterectomies are decreasing, a new study of more than three thousand women in Michigan who underwent hysterectomy for benign indications reveals that alternatives to hysterectomy are being underused and that treatment guidelines are often not followed.

7 Jan 2015

CytRx reports positive interim results from aldoxorubicin Phase 2 trial for treatment of GBM

CytRx Corporation, a biopharmaceutical research and development company specializing in oncology, today announced positive interim results from its ongoing Phase 2 clinical trial with aldoxorubicin for the treatment of unresectable glioblastoma multiforme (GBM), a deadly form of brain cancer.

6 Jan 2015

Many breast cancer patients undergoing lumpectomy surgery benefit from new intra-operative technology

Many patients undergoing lumpectomy surgery at NYU Langone Medical Center for the removal of an early detected breast tumor - the surgical option of choice for this diagnosis -- are benefitting from new intra-operative technology that detects microscopic amounts of cancer cells on removed tumor tissue not visible during or following surgical intervention.

6 Jan 2015

Rich, educated, single males drink more in later life

A decade long research project into the drinking habits of over 45s has found that rich, educated, single males are at greatest risk of failing to cut their drinking habits in later life.

5 Jan 2015

Cardiac arrest associated with high mortality even in the world of Star Trek

The Star Trek universe is one of the most popular pieces of science fiction entertainment. Lots of the technologies seen in the TV and cinema episodes featuring Captain Kirk, Mr Spock or Captain Picard were once regarded as futuristic, but have now become reality - with examples including wireless communication or portable computers. In a recent study by the University Department of Emergency Medicine at the MedUni Vienna, the make-believe future of the human race depicted in this series has been used to investigate the frequency and mortality of cardiac arrests in the 24th century.

1 Jan 2015

Novel device may speed up medical decision-making for critically injured trauma patients

A tool that surgeons use for monitoring a patient's blood level in physicians' offices may also save valuable minutes in medical decision-making for critically injured trauma patients, according to study results published in the January 2015 issue of the Journal of the American College of Surgeons.

30 Dec 2014

Negative health effects of severe obesity

The negative health effects of severe obesity are very well known and have been thoroughly documented, yet obesity levels in the United States continue to remain stubbornly high. Many of these repercussions are life threatening and include heart attack, stroke, and a greatly increased chance of developing cancer.

27 Dec 2014

Radiation/chemotherapy increases risk of leukemia in early-stage breast cancer patients

The risk of developing leukemia after radiation therapy or chemotherapy for early stage breast cancer remains very small, but it is twice as high as previously reported, according to results of a new study led by researchers at the Johns Hopkins Kimmel Cancer Center.

23 Dec 2014

Preventing gas chromatography (GC) leaks

Leaks at gas chromatography (GC) column connections are a common source of frustration and wasted time in laboratories. Time is often spent manually tightening connections between columns using a handheld tool – time which could otherwise be spent analyzing results or running more investigations. Preventing GC leaks has become a priority for researchers looking to save time and money while achieving high quality results.

From Agilent Technologies - Mass Spectrometry 23 Dec 2014

Frequency News and Research

Study: Mutated ATRX gene may serve as much-needed biomarker for rare neuroendocrine tumors

Exposure to alcohol TV ads associated with underage drinking

MET amplified in NSCLC irrespective of type, genetic background

Effective vaccine booster schedules needed to fight against whooping cough resurgence

Researchers turn clinical experience in multiple myeloma treatment into instructive review for physicians

Scientists identify first genetic marker linked to severe neurological toxicity

Researchers develop novel method to predict risk of liver cancer recurrence after transplantation

eAgile releases new UHF EPC compliant MicroWing inlay

EGFR mutations, ALK translocations not mutually exclusive in NSCLC

Survey shows radiation oncologists desire for more formal guidance to improve peer review process

Capsule Tech announces availability of healthcare's first medical device information system

Study finds unnecessary hysterectomy in 1 out of 5 cases

CytRx reports positive interim results from aldoxorubicin Phase 2 trial for treatment of GBM

Many breast cancer patients undergoing lumpectomy surgery benefit from new intra-operative technology

Rich, educated, single males drink more in later life

Cardiac arrest associated with high mortality even in the world of Star Trek

Novel device may speed up medical decision-making for critically injured trauma patients

Negative health effects of severe obesity

Radiation/chemotherapy increases risk of leukemia in early-stage breast cancer patients

Preventing gas chromatography (GC) leaks

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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