Genes News and Research

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‘Foreign body reaction’ to implants can be reduced by incorporating drug into silicone coating

Long-term use of implantable electronic medical devices – such as pacemakers and cochlear implants – is hampered by the body's reaction to foreign bodies.

14 Mar 2022

Using mRNA to introduce gene editor into human muscle stem cells

Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.

14 Mar 2022

Scientists map key molecular changes during mouse embryogenesis

Scientists have mapped out the key molecular changes that orchestrate how embryonic mouse cells differentiate into the diverse cell types that will ultimately form all the different tissues and organs of the adult animal.

14 Mar 2022

Can wearables transform the future of healthcare?

In partnership with SLAS 2022, we spoke to Professor Michael Snyder about his latest research that investigates wearables and their future within healthcare.

From Society for Laboratory Automation and Screening (SLAS) 14 Mar 2022

New computational biology method deciphers gut microbiome ‘chatter’ to fight IBD

Around 500,000 people in the UK live with Inflammatory Bowel Disease (IBD), a life-long, chronic condition characterized by sporadic bouts of gut inflammation causing debilitating symptoms.

14 Mar 2022

Study explores SARS-CoV-2 viremia kinetics

In a new study, researchers evaluated the kinetics of severe acute respiratory syndrome coronavirus-2 viremia.

14 Mar 2022

Current evidence that vitamin D is effective against COVID-19 neurological sequelae

Researchers analyze the available scientific evidence supporting vitamin D as a neuroprotective agent against the neurological sequelae of COVID-19.

14 Mar 2022

Bioactive small molecules enhance CRISPR/Cas9 loss-of-function editing in human cells

Researchers demonstrate enhanced loss-of-function editing of CRISPR/Cas9 in human cells.

14 Mar 2022

Researchers develop a system of synthetic biosensors to assess the response of cancer therapy

Immune checkpoint blockade (ICB) inhibitors have transformed the treatment of cancer and have become the frontline therapy for a broad range of malignancies. It's because they work better than the previous standard of care.

11 Mar 2022

Tumor cells’ 'ferroaddiction' can be exploited to deliver powerful anticancer drugs

Researchers at the University of California, San Francisco, have discovered that cells carrying the most common mutation found in human cancer accumulate large amounts of ferrous iron and that this "ferroaddiction" can be exploited to specifically deliver powerful anticancer drugs without harming normal, healthy cells.

11 Mar 2022

Exploring SARS-CoV-2 spike evolution in relation to sensitivity to antiviral restriction factors

Researchers investigated the effects of SARS-CoV-2 spike mutations on antiviral restriction mediated by interferon-induced transmembrane proteins and guanylate binding proteins.

11 Mar 2022

Novel genetic relationships with severe SARS-CoV-2

Researchers discovered multiple novel genetic processes underpinning severe COVID-19 using genome-wide association studies and meta-analyses.

11 Mar 2022

Further optimization of cysteine-reactive pyrazoline-based covalent inhibitors for the SARS-CoV-2 Mpro

Researchers discovered and optimized cysteine-reactive pyrazoline-based covalent inhibitors for several coronaviruses' Mpro, including SARS-CoV-2.

11 Mar 2022

Scientists identify a new protein that turbocharges gene expression

For many years, scientists have sought to understand what happens when our genes are flipped to the "on" position. Now, scientists at the University of California San Diego and Rutgers University have identified a new protein that contributes to this important process.

11 Mar 2022

Genomic surveillance of bacterial colonies could help physicians keep closer tabs on drug resistance

Antibiotic-resistant bacterial infections are difficult to treat and cause more than a million annual deaths worldwide, especially in hospitalized patients with pneumonia, bloodstream infections, urinary tract infections, or abdominal infections.

11 Mar 2022

Pioneering kidney disease research at Leicester receives a major boost on World Kidney Day

Pioneering research by the University of Leicester into chronic kidney disease has received a major boost on World Kidney Day (10th March 2022) following a generous £1million donation from long-term supporter and kidney health advocate Jimmy Mayer.

10 Mar 2022

Novel strategy for data sharing may help better understand disease-causing genetic variants

Scientists may better understand and test for the genetic variations that cause cancer and other heritable diseases through the application of a novel strategy for securely sharing and analyzing genomic data developed at the UC Santa Cruz Genomics Institute.

10 Mar 2022

Genes News and Research

‘Foreign body reaction’ to implants can be reduced by incorporating drug into silicone coating

Using mRNA to introduce gene editor into human muscle stem cells

Scientists map key molecular changes during mouse embryogenesis

Can wearables transform the future of healthcare?

New computational biology method deciphers gut microbiome ‘chatter’ to fight IBD

Study explores SARS-CoV-2 viremia kinetics

Current evidence that vitamin D is effective against COVID-19 neurological sequelae

Bioactive small molecules enhance CRISPR/Cas9 loss-of-function editing in human cells

Researchers develop a system of synthetic biosensors to assess the response of cancer therapy

Tumor cells’ 'ferroaddiction' can be exploited to deliver powerful anticancer drugs

Exploring SARS-CoV-2 spike evolution in relation to sensitivity to antiviral restriction factors

Novel genetic relationships with severe SARS-CoV-2

Further optimization of cysteine-reactive pyrazoline-based covalent inhibitors for the SARS-CoV-2 Mpro

Scientists identify a new protein that turbocharges gene expression

Genomic surveillance of bacterial colonies could help physicians keep closer tabs on drug resistance

Pioneering kidney disease research at Leicester receives a major boost on World Kidney Day

Novel strategy for data sharing may help better understand disease-causing genetic variants

Scientists identify a molecular regulator involved in resistance to breast cancer treatment

LMU scientists find specific immunological signature that can prevent SARS-CoV-2 virus spread

Study reveals differential blood glycoprotein profiles in symptomatic and asymptomatic COVID-19 patients

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo