Lungs News and Research

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Prediagnostic lung function impairment common in older asthma patients

Older adults with newly diagnosed asthma are not only more likely to have pre-existing lung function impairment than younger adults, but they also experience a more rapid decline of lung function, a Danish team reports in Respiratory Medicine.

21 May 2015

Johns Hopkins scientists safely use immune cells to treat multiple myeloma

In a report on what is believed to be the first small clinical trial of its kind, researchers at the Johns Hopkins Kimmel Cancer Center say they have safely used immune cells grown from patients' own bone marrow to treat multiple myeloma, a cancer of white blood cells.

21 May 2015

Enterprise Therapeutics secures additional funding to accelerate drug discovery for treatment of respiratory diseases

ENTERPRISE THERAPEUTICS Ltd, a drug discovery company focused on new therapeutics for respiratory diseases, today announced that it has secured an additional £2.4m ($3.6m) in Series-A financing.

21 May 2015

Scripps Proton Therapy Center reports exceptional results in treating patients with pencil-beam scanning

The nation's first and only proton therapy center to treat patients exclusively with pencil-beam scanning is reporting exceptional results in delivering cancer treatment since opening for patient care just more than a year ago.

21 May 2015

Research may offer new targets for diagnosing, treating advanced prostate cancer

Researchers with the Indiana University School of Medicine have identified a molecule that promotes metastasis of advanced prostate cancer to the bone, an incurable condition that significantly decreases quality of life.

20 May 2015

Discovery Lab enrolls first patient in phase 2a clinical trial of AEROSURF

Discovery Laboratories, Inc., a specialty biotechnology company focused on developing aerosolized KL4 surfactant therapies for respiratory diseases, today reported that the first patient has been enrolled in the next phase of its phase 2a clinical evaluation of AEROSURF, which is designed to evaluate the safety and tolerability of higher and repeat doses of aerosolized KL4 surfactant administered to premature infants 29 to 34 weeks gestational age (GA) who are receiving nasal continuous positive airway pressure (nCPAP) for respiratory distress syndrome (RDS), compared to infants receiving nCPAP alone.

20 May 2015

Johns Hopkins researchers identify new therapy to treat lung cancer

A multidisciplinary team led by Johns Hopkins researcher Venu Raman, Ph.D., with notable contributions from Guus Bol, Farhad Vesuna and Phuoc Tran of Johns Hopkins, has identified a new therapy for lung cancer, the most common cancer worldwide. The therapy has been in development for six years and involves a first-in-class molecule designed by the team.

20 May 2015

Lakewood-Amedex's novel class of antimicrobials prove effective at killing MDR-TB strains

Lakewood-Amedex Inc., a leading developer of novel anti-infective pharmaceuticals, announced today that a recent series of in vitro studies conducted by Southern Research in Birmingham, Alabama, have demonstrated that its novel class of antimicrobials, named bisphosphocins, have proven effective at killing multidrug-resistant (MDR) strains of Mycobacterium tuberculosis, the bacteria responsible for the chronic lung infection tuberculosis.

19 May 2015

University of Missouri researchers identify key protein component that causes cystic fibrosis

Nearly 70,000 people worldwide are living with cystic fibrosis, a life-threatening genetic disease. There currently is no cure for the condition, but researchers from the University of Missouri have identified a key component in the protein that causes the disease. It is a finding that may lay the foundation for the development of new medications and improved therapies.

19 May 2015

Study: Air pollution, impaired lung function independently affect cognition

Studies have shown that both air pollution and impaired lung function can cause cognitive deficits, but it was unclear whether air pollution diminishes cognition by reducing breathing ability first or whether air pollution represents an independent risk factor for cognitive deficit.

19 May 2015

Two-drug combination improves lung function in some cystic fibrosis patients

The combination of two drugs — an investigational drug used in conjunction with an already FDA-approved medication — improved lung function in patients with one form of cystic fibrosis, according to two new studies.

19 May 2015

Pre-pregnancy maternal weight has significant impact on baby's immune system

Almost 60 percent of women of childbearing age in the United States are overweight or obese. Obesity is a major public health issue, and has been linked to health problems like heart disease, cancer and hypertension. It can complicate pregnancy by increasing the mother's risk of having gestational diabetes, preeclampsia, preterm birth or a baby with birth defects. Maternal obesity is also linked to several adverse health outcomes for the infant that can persist into adulthood, such as type-2 diabetes, heart disease and mortality.

19 May 2015

Blood-thinning treatment safe for patients with brain metastases

Cancer patients with brain metastases who develop blood clots may safely receive blood thinners without increased risk of dangerous bleeding, according to a study, published online today in Blood, the Journal of the American Society of Hematology.

19 May 2015

Alnylam files clinical trial application for alpha-1 liver disease, presents data at DDW

Alnylam Pharmaceuticals, Inc. has announced that it has filed a Clinical Trial Application (CTA) with the U.K. Medicines and Healthcare products Regulatory Agency (MHRA) to initiate a Phase 1/2 clinical trial with ALN-AAT, a subcutaneously administered investigational RNAi therapeutic targeting alpha-1 antitrypsin (AAT) for the treatment of AAT deficiency-associated liver disease (alpha-1 liver disease).

19 May 2015

Regular use of aspirin may slow the progression of early emphysema, new research shows

Regular use of aspirin may help slow the progression of early emphysema, according to new research presented at the 2015 American Thoracic Society International Conference.

18 May 2015

Weight loss can improve outcomes in lung transplant patients

Obesity is a complicating factor for many surgical patients. In a recent study published in the Journal of Heart and Lung Transplantation, Mayo Clinic researchers have shown that losing weight can have a positive impact on outcomes for lung transplant patients.

18 May 2015

E-cigarette liquid flavors may alter key cellular functions in lung tissue

Certain flavorings used in electronic cigarette liquid may alter important cellular functions in lung tissue, according to new research presented at the 2015 American Thoracic Society International Conference.

18 May 2015

Combined therapy shows promise in cystic fibrosis patients

Treatment with two medications that target the most common genetic cause of cystic fibrosis improves lung function and lowers the rate of pulmonary exacerbations, according to the results from a Phase III international clinical trial published online in the New England Journal of Medicine on May 17, 2015.

17 May 2015

Differences in mechanical, chemical makeup of e-cigarettes can have adverse effects on human health

Unlike standard cigarettes, the components of electronic cigarettes are not regulated and standardized, thus they vary widely between products.

17 May 2015

New affordable advanced NGS cancer test launched by EKF subsidiary

This new NGS panel molecular test is an important step towards readily accessible and affordable personalized medicine in cancer...

From EKF Diagnostics 15 May 2015

Lungs News and Research

Prediagnostic lung function impairment common in older asthma patients

Johns Hopkins scientists safely use immune cells to treat multiple myeloma

Enterprise Therapeutics secures additional funding to accelerate drug discovery for treatment of respiratory diseases

Scripps Proton Therapy Center reports exceptional results in treating patients with pencil-beam scanning

Research may offer new targets for diagnosing, treating advanced prostate cancer

Discovery Lab enrolls first patient in phase 2a clinical trial of AEROSURF

Johns Hopkins researchers identify new therapy to treat lung cancer

Lakewood-Amedex's novel class of antimicrobials prove effective at killing MDR-TB strains

University of Missouri researchers identify key protein component that causes cystic fibrosis

Study: Air pollution, impaired lung function independently affect cognition

Two-drug combination improves lung function in some cystic fibrosis patients

Pre-pregnancy maternal weight has significant impact on baby's immune system

Blood-thinning treatment safe for patients with brain metastases

Alnylam files clinical trial application for alpha-1 liver disease, presents data at DDW

Regular use of aspirin may slow the progression of early emphysema, new research shows

Weight loss can improve outcomes in lung transplant patients

E-cigarette liquid flavors may alter key cellular functions in lung tissue

Combined therapy shows promise in cystic fibrosis patients

Differences in mechanical, chemical makeup of e-cigarettes can have adverse effects on human health

New affordable advanced NGS cancer test launched by EKF subsidiary

The ultimate guide to lung research tools and protocols eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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