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New immunotoxin found to be safe, effective in patients with B-cell malignancies

Almost all patients with a group of blood cancers called B-cell malignancies have two prominent "fingerprints" on the surface of leukemia and lymphoma cancers, called CD22 and CD19, Vallera explained.

13 Mar 2015

Researchers develop 'warhead' molecule that targets deadly bacteria, spares healthy cells

Targeting deadly, drug-resistant bacteria poses a serious challenge to researchers looking for antibiotics that can kill pathogens without causing collateral damage in human cells.

13 Mar 2015

New method could help understand functions of gut microbiome

Researchers at Harvard Medical School and Columbia University in the United States have developed a way to study the functions of hard-to-grow bacteria that contribute to the composition of the gut microbiome. The new method is published in the journal Molecular Systems Biology.

12 Mar 2015

Scientists find strong association between MAIT lymphocytes and metabolic dysfunctions

Scientists at Institut Cochin (CNRS/Inserm/Université Paris Descartes) and ICAN - Institute of Cardiometabolism And NutritionInserm/UPMC/AP-HP) have discovered that a class of inflammatory cells, MAIT lymphocytes1, is deregulated in patients suffering from type 2 diabetes and obesity.

12 Mar 2015

Study shows that households can serve as reservoir for transmitting MRSA

Households can serve as a reservoir for transmitting methicillin-resistant Staphylococcus aureus (MRSA), according to a study published this week in mBio, the online open-access journal of the American Society for Microbiology. Once the bacteria enters a home, it can linger for years, spreading from person to person and evolving genetically to become unique to that household.

10 Mar 2015

Viagra can have anti-cancer, anti-Alzheimer's disease effects if used with new drugs

Chaperone proteins play an important role in protein folding in human cells and in bacteria and are promising new targets for drugs to treat cancer and Alzheimer's disease and for novel antiviral drugs and antibiotics. How existing drugs such as Viagra or Cialis and a derivative of the drug Celebrex, for example, can reduce the activity of a specific chaperone protein, with the potential for anti-tumor and anti-Alzheimer's disease effects, is described in a Review article in DNA and Cell Biology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

10 Mar 2015

Researchers take images of tiny molecular machine that bacteria use to infect host cells

Armed with a microscope capable of zooming in on organisms measured in billionths of a meter, scientists report they are the first to observe one of the tiny molecular machines that bacteria use to infect host cells. Findings appear in the Proceedings of the National Academy of Sciences.

10 Mar 2015

Preventing lung infections in childhood could help people with cystic fibrosis during adulthood

Preventing lung infections in childhood could stop later life-threatening infections for people with cystic fibrosis (CF), according to the latest research carried out at Aston University.

6 Mar 2015

Better interventions possible for children experiencing acute psychosis with antibodies

Antibodies defend the body against bacterial, viral, and other invaders. But sometimes the body makes antibodies that attack healthy cells. In these cases, autoimmune disorders develop.

6 Mar 2015

Low-cost antiseptic could help reduce deaths in newborn babies

A low-cost antiseptic used to cleanse the cord after birth could help reduce infant death rates in developing countries by 12%, a systematic review published in The Cochrane Library suggests. Authors of the review found that when chlorhexidine was used on babies born outside of a hospital, it reduces the number of newborn babies who died or suffer from infections.

5 Mar 2015

University of Adelaide study reveals how metal cadmium causes toxicity in living cells

University of Adelaide research has uncovered how the metal cadmium, which is accumulating in the food chain, causes toxicity in living cells.

5 Mar 2015

Symbiomix Therapeutics announces positive results from SYM-1219 Phase 1 clinical program

Symbiomix Therapeutics, a late-stage, privately held biopharmaceutical company developing innovative medicines for serious women's health infections, today announced results from its Phase 1 clinical program demonstrating that its lead product candidate, SYM-1219, was safe and well tolerated and had predictable pharmacokinetics (PK), and that contraceptive efficacy for birth control pills would not be altered by SYM-1219 administration.

4 Mar 2015

Study: Pregnant women need to avoid antibiotics to prevent asthma development in children

Getting sick when you're pregnant is especially difficult, but women whose children are at risk for developing asthma should avoid antibiotics, according to a new study.

4 Mar 2015

Salt may help control infection

Researchers at Vanderbilt University and in Germany have found that sodium - salt - accumulates in the skin and tissue in humans and mice to help control infection.

4 Mar 2015

Researchers reveal how bacterial molecule controls the body's response to TB infection

The cascade of events leading to bacterial infection and the immune response is mostly understood. However, the molecular mechanisms underlying the immune response to the bacteria that causes tuberculosis have remained a mystery — until now. Researchers at the Johns Hopkins University School of Medicine have now uncovered how a bacterial molecule controls the body's response to TB infection and suggest that adjusting the level of this of this molecule may be a new way to treat the disease.

3 Mar 2015

Minihepcidin reverses iron overload of hemochromatosis, stops susceptibility to infections

Hemochromatosis (HH) is the most common genetic disorder in the western world, and yet is barely known. Only in the US 1 in 9 people carry the mutation (although not necessarily the disease).

2 Mar 2015

KU Leuven researchers devise simple, effective solution to untangle DNA

Researchers have long sought an efficient way to untangle DNA in order to study its structure - neatly unraveled and straightened out - under a microscope. Now, chemists and engineers at KU Leuven, in Belgium, have devised a strikingly simple and effective solution: they inject genetic material into a droplet of water and use a pipet tip to drag it over a glass plate covered with a sticky polymer.

27 Feb 2015

Emulsifiers can alter gut microbiota composition to induce intestinal inflammation

Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter the gut microbiota composition and localization to induce intestinal inflammation that promotes the development of inflammatory bowel disease and metabolic syndrome, new research shows.

26 Feb 2015

Study reveals causes of community-acquired pneumonia in children

With the chill of winter comes a spike in community-acquired pneumonia (CAP), which spreads more easily as people retreat indoors and come into close contact. The lung infection triggers persistent coughing, chest pain, fever, and difficulty breathing, and is particularly hard on the very young and the very old. In fact, pneumonia is the leading cause of hospitalization among U.S. children, with estimated medical costs of $1 billion annually.

26 Feb 2015

Study points respiratory viruses as the most common cause of childhood pneumonia

Respiratory viruses, not bacterial infections, are the most commonly detected causes of community-acquired pneumonia in children, according to new research released Feb. 26 in the New England Journal of Medicine.

26 Feb 2015

Bacterial News and Research

New immunotoxin found to be safe, effective in patients with B-cell malignancies

Researchers develop 'warhead' molecule that targets deadly bacteria, spares healthy cells

New method could help understand functions of gut microbiome

Scientists find strong association between MAIT lymphocytes and metabolic dysfunctions

Study shows that households can serve as reservoir for transmitting MRSA

Viagra can have anti-cancer, anti-Alzheimer's disease effects if used with new drugs

Researchers take images of tiny molecular machine that bacteria use to infect host cells

Preventing lung infections in childhood could help people with cystic fibrosis during adulthood

Better interventions possible for children experiencing acute psychosis with antibodies

Low-cost antiseptic could help reduce deaths in newborn babies

University of Adelaide study reveals how metal cadmium causes toxicity in living cells

Symbiomix Therapeutics announces positive results from SYM-1219 Phase 1 clinical program

Study: Pregnant women need to avoid antibiotics to prevent asthma development in children

Salt may help control infection

Researchers reveal how bacterial molecule controls the body's response to TB infection

Minihepcidin reverses iron overload of hemochromatosis, stops susceptibility to infections

KU Leuven researchers devise simple, effective solution to untangle DNA

Emulsifiers can alter gut microbiota composition to induce intestinal inflammation

Study reveals causes of community-acquired pneumonia in children

Study points respiratory viruses as the most common cause of childhood pneumonia

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