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Study suggests potential new approach to treat atopic dermatitis

How does the immune system respond to fungi on our skin? Researchers at the University of Zurich have demonstrated that the same immune cells that protect us against skin fungi also encourage the inflammatory symptoms of atopic dermatitis. An antibody therapy could alleviate this chronic inflammatory skin disease.

18 Mar 2019

Long-awaited structure offers new insights into rejection of transplanted organs

Rejection of any kind is always hard to deal with, but when one's body rejects a precious organ transplant, the consequences can be devastating. Professor A. Vathsala, Co-director of the National University Centre for Organ Transplantation at the National University Hospital and Professor of Medicine, shared that between 30% to 40% of kidney transplants are lost over time to rejection.

15 Mar 2019

Fingermark imaging for identification of drugs

In a paper to be published in the forthcoming issue in NANO, researchers from Zhejiang have uncovered a novel method of using nanocarrier-based biological fluorescent probes for detecting amphetamine and ketamine in latent fingermark, in a bid to combat drug abuse.

15 Mar 2019

Researchers define pathway that helps us make antibodies

Our bodies are continuously concocting specific antibodies to thwart invaders like a virus or even pollen, and scientists have new information about how the essential production gets fired up and keeps up.

13 Mar 2019

Association found between gene variant and lung disease in the form of systemic vasculitis

University of Tsukuba-led team reveals the association between a gene variant and a lung disease in the form of systemic vasculitis particularly prevalent in the Japanese, potentially providing a target for future therapies.

13 Mar 2019

Study uncovers potential new strategy to treat influenza A

A team of researchers from Scripps Research and Janssen Research & Development LLC has discovered an orally active small molecule that neutralizes influenza A group 1 viruses, the most common flu strains.

11 Mar 2019

Blood donors' leftover immune cells provide crucial insights into antibody affinity

During some kinds of blood donations, you get most of your blood back. For example, platelet donation involves a procedure in which donor blood is filtered to harvest the platelets for medical use and the rest of the blood components are returned to the donor's body.

11 Mar 2019

Mechanism through which bacteria attack the immune system discovered

A research team led by Prof. Dr. Winfried Römer and Dr. Elias Hobeika from the University of Freiburg and the University Medical Center in Ulm has discovered a mechanism with which bacteria activate white blood cells and attack an organism's immune system. The scientists recently published the results in the journal Science Signaling.

7 Mar 2019

ACROBiosystems collaborates with ProMab Biotechnologies to develop immunotherapy products

ACROBiosystems, a leading manufacturer of recombinant proteins, announced that they have signed a collaboration agreement with ProMab Biotechnologies, a leading manufacturer of monoclonal antibodies and CAR-T cells.

From ACROBiosystems 7 Mar 2019

AvantGen and ACROBiosystems sign vendor agreement

AvantGen Inc., a world-leading CRO for human and rabbit antibody discovery and optimization, and ACROBiosystems Inc., a global biotech company specializing in recombinant protein technology jointly announced the signing of a preferred vendor agreement between the parties.

From ACROBiosystems 7 Mar 2019

Better regulation of the immune system may help manage preeclampsia

Boosting the body's levels of interleukin-4 (IL-4)--an immune system protein that controls inflammation--may help manage the pregnancy complication preeclampsia, according to a new rodent study.

7 Mar 2019

Research offers new hope for seasonal allergy sufferers

One in three people is plagued by an allergy, triggered by foodstuffs, fungi, house dust mites or on a seasonal basis due to pollen. The latter group is the largest: around 800 million people worldwide suffer from some form of allergy to pollen, with the usual symptoms such as a runny nose, cough and severe breathing problems.

6 Mar 2019

EAF4 module determines physicochemical, biophysical attributes of monoclonal antibodies

Postnova Analytics Inc. reports how its Electrical Asymmetrical Flow Field Flow Fractionation and Size Exclusion Chromatography modules have been used to determine the physicochemical and biophysical attributes of monoclonal antibodies.

From Postnova Analytics 6 Mar 2019

Nano therapy reverses deadliest effects of chronic kidney disease in animal model

By loading a chelation drug into a nano-sized homing device, researchers at Clemson University have reversed in an animal model the deadliest effects of chronic kidney disease, which kills more people in the United States each year than breast or prostate cancer.

5 Mar 2019

Researchers examine process of gut-based cells involved in long-term immunity

Only a few vaccines - for example, against polio and rotavirus - can be given orally. Most must be delivered by injection.

5 Mar 2019

Universal pan-filovirus T-cell vaccine could offer protection against Ebola and Marburg

Vaccines that induce protective T-cell responses could protect against members across the filovirus family, according to a study published February 28 in the open-access journal PLOS Pathogens by Tomáš Hanke of the University of Oxford, Bette Korber of the Los Alamos National Laboratory, and colleagues.

4 Mar 2019

Mother's dengue immunity influences the severity of Zika infection in infants

Researchers at Duke-NUS Medical School and their colleagues have identified a surprising interaction between dengue and Zika viruses that sheds lights on the significant fetal brain abnormalities linked to Zika virus.

1 Mar 2019

Translucent wonder material used on stadium roofs helps measure protein particles

Understanding how proteins clump together is essential in modern pharmaceuticals. When these tiny particles aggregate, they can alter the effectiveness of both vaccines and drugs, especially many of the new, popular formulations derived from monoclonal antibodies.

1 Mar 2019

Custom-made proteins could result in antibodies that fight HIV

Researchers have developed a new method for the creation of custom-made proteins that can bypass the protective coating of the HIV virus.

28 Feb 2019

Researchers reveal promising biomarker for vascular disease relapse

Researchers at Okayama University report in the journal Arthritis & Rheumatology that monitoring a particular antigen can be used for predicting relapse of the vascular disease AAV.