Cancer Therapy News and Research

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Short-term severe calorie restriction safe, feasible, and well tolerated by cancer patients

A diet involving short-term, severe calorie restriction was safe, feasible, and resulted in a decrease of blood glucose and growth factor concentration, reduction in peripheral blood immunosuppressive cells, and enhanced intratumor T-cell infiltration in cancer patients receiving standard-of-care therapy, according to the results of a clinical trial.

18 Nov 2021

Young adults with cancer may require different treatments than older patients

Not all tumors are alike. Young adults who are diagnosed with skin, colon, and other cancer types may require different treatments than older patients receive.

16 Nov 2021

Machine learning analysis of long non-coding RNAs reveals new prognostic cancer biomarkers

A new batch of prognostic cancer biomarkers have been discovered in an area where few have gone looking before. Researchers have unveiled a catalogue of 166 prognostic biomarkers, generated by analyzing long non-coding RNAs (lncRNAs) – which are understudied in cancer research.

15 Nov 2021

Drug combination highly effective in children with standard- and high-risk acute promyelocytic leukemia

A clinical trial has found that the combination of all-trans retinoic acid, which is a metabolite of vitamin A, and arsenic trioxide is highly effective in children with standard- and high-risk acute promyelocytic leukemia, or APL.

11 Nov 2021

Inhibiting epigenetic modification could be key to reducing cancer metastasis

Fatty acid uptake produces an epigenetic modification that is required for cancer metastasis, according to a study published in Nature.

10 Nov 2021

Key link between chronic stress and cancer discovered

Stress can have a significant negative effect on health, but our understanding of how stress impacts the development and progression of cancer is just beginning.

6 Nov 2021

Study identifies how cancer cells transform macrophages into supporters of their growth

A Ludwig Cancer Research study has identified a means by which cancer cells engineer the conversion of immune cells known as macrophages from destroyers of tumors to supporters of their growth and survival.

26 Oct 2021

Study reveals dual role of anti-cancer inhibitor

TG2, an enzyme known to help cancers spread more quickly, also plays a role in regulating T-cells, according to a Northwestern Medicine study published in the Journal for Immunotherapy of Cancer.

21 Oct 2021

Study offers clues to why calorie-restricted diet may slow tumor growth

In recent years, there has been some evidence that dietary interventions can help to slow the growth of tumors.

20 Oct 2021

Cancer patients on chemotherapy have lower immune response to COVID-19 vaccine, study finds

The COVID-19 pandemic has been an especially stressful time for cancer patients undergoing chemotherapy, which attacks not only the cancer, but also the immune cells needed to defend the body from infections.

2 Oct 2021

Researchers develop fluorescence quenching assay to probe the integrity of cell membrane coating

Cell membrane coated biomimetic nanoparticles (NPs) have been widely studied in nanomedicine because of their unique properties such as immune escaping, long blood circulation, specific molecular recognition and efficient cancer targeting, indicating a great potential in targeted cancer therapy.

30 Sep 2021

Combination of two drugs may help pancreatic and liver cancer patients

A drug candidate discovered and developed decades ago in the laboratory of UC Davis distinguished professor Bruce Hammock may help control the body's raging and often deadly inflammatory response to chemotherapy treatments, especially for pancreatic and liver cancer patients.

29 Sep 2021

New discovery offers clues to overcoming resistance to cancer therapies

Cancer cells proliferate despite a myriad of stresses - from oxygen deprivation to chemotherapy - that would kill any ordinary cell.

23 Sep 2021

Oxford COVID vaccine technology has the potential to revolutionize cancer treatment

Scientists from the University of Oxford and the Ludwig Institute for Cancer Research are building on the success of the Oxford-AstraZeneca vaccine against SARS-CoV-2 to develop a vaccine to treat cancer.

21 Sep 2021

Researchers reveal a mechanism of SHP2-mediated tumor immunosuppression

Colorectal cancer (CRC), a malignant tumor worldwide consists of microsatellite instability (MSI) and stable (MSS) phenotypes. Although SHP2 is a hopeful target for cancer therapy, its relationship with innate immunosuppression remains elusive. To address that, the authors of this article performed single-cell RNA sequencing to explore the role of SHP2 in all cell types of tumor microenvironment (TME) from murine MC38 xenografts.

21 Sep 2021

NCTN trials gave 14 million years of additional life to cancer patients, analysis finds

Over the past 40 years, people in the U.S. diagnosed with cancer gained 14 million years of additional life thanks to the results of cancer clinical trials conducted by the National Cancer Institute's publicly funded National Clinical Trials Network, according to an analysis to be reported September 20, 2021, at the annual meeting of the European Society for Medical Oncology.

20 Sep 2021

Study discovers biological mechanism linking long-term arsenic exposure to cancer, diabetes

A University of Arizona Health Sciences study has identified the biological mechanism linking long-term arsenic exposure to diseases such as cancer and Type 2 diabetes.

15 Sep 2021

MD Anderson and SNIPR BIOME join forces to advance new CRISPR-based microbiome therapeutics

The University of Texas MD Anderson Cancer Center and SNIPR BIOME today announced a strategic collaboration to advance new CRISPR-based microbiome therapeutics to reduce immune-related adverse events (irAE) in patients being treated with combined immune checkpoint inhibitors.

13 Sep 2021

Physical exercise can improve cancer-induced anemia

Many cancer patients suffer from anemia leaving them fatigued, weak, and an impaired ability to perform physical activity.

9 Sep 2021

Advancements in the diagnosis and treatment of prostate cancer are saving more lives

Prostate cancer is the most common type of cancer among men in the United States aside from skin cancer, according to the Centers for Disease Control and Prevention.

8 Sep 2021