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Daily aspirin use may help prevent colorectal cancer

A new study has shown that regular use of aspirin may protect against heart disease, reduce colorectal tumor growth and prevent relapse.

7 Jan 2020

New antibody-drug conjugate shows promising activity in salivary gland tumors

The antibody-drug conjugate ado-trastuzumab emtansine (T-DM1) has promising activity in HER2 amplified salivary gland tumors, according to data published in the Annals of Oncology.

7 Jan 2020

Aspirin’s benefits may extend beyond heart health to colorectal cancer treatment

The benefits of a daily aspirin may extend beyond heart health to colorectal cancer treatment, say City of Hope researchers who have found aspirin appears to reduce tumor growth and inhibit recurrence of the disease.

6 Jan 2020

Common plasticizer leads to fertility problems in roundworms

A new study published 9th January in PLOS Genetics by Mónica Colaiácovo of Harvard Medical School and colleagues reports that the most commonly used plasticizer, diethylhexyl phthalate, leads to fertility problems by causing an excess number of breaks in the DNA during egg production, and then interfering with the repair systems that fixes the breaks.

2 Jan 2020

p53 may play a more important role in kidney cancer than previously thought

The p53 gene, which researchers had thought was less relevant in kidney cancer, may play an important role after all – a discovery that could lead to new treatments.

20 Dec 2019

Glutamine could help obese people reduce inflammation of fat tissue

Glutamine could help people with obesity reduce inflammation of fat tissue and reduce fat mass, according to a new study at Karolinska Institutet in Sweden and the University of Oxford in the U.K. The researchers also show how glutamine levels can alter gene expression in several different cell types.

19 Dec 2019

Yale researchers identify cellular chicanery that jumpstarts cancer

The progression of cancer has been studied extensively, and the key steps in this journey have been well mapped, at least in some solid tumors: Lesions to genes that confer risk of cancer accumulate and alter normal cell behaviors, giving rise, scientists believe, to early stage cancer cells that eventually swamp normal cells and become deadly.

18 Dec 2019

Extrachromosomal circular DNA can contribute to cancer development in children

Cancer development is associated with the gradual accumulation of DNA defects over time. Thus, cancer is considered an age-related disease.

17 Dec 2019

New strategy could prevent side effects of targeted cancer treatment

Targeted, highly effective cancer treatments often produce debilitating side effects. This is the case with one commonly used therapy which works by blocking the epidermal growth factor receptor, a protein that stimulates cell proliferation.

13 Dec 2019

Epigenome editing could repair genetic brain disorder

A new study published in the journal Nature Communications shows that it may be possible to reverse gene mutations that cause brain disorders, using a very precisely targeted epigenome editing technique. This type of gene editing does not change the gene’s DNA sequence itself but is focused on correcting epigenome changes only. The condition that was corrected in the study is called the WAGR syndrome and is associated with obesity and intellectual disability in people.

11 Dec 2019

New drug combo promises help for triple negative breast cancer patients

A new preclinical study on triple negative breast cancer (TNBC) reports that an experimental polo-like kinase 1 (PLK1) inhibitor shrank tumor four times more powerfully when used along with standard drugs than alone. The study, reported in the journal PLOS ONE, opens up a new door of opportunity for patients with this disease.

11 Dec 2019

New discovery on chromosomal function may shed light on human health and disease

Researchers have discovered key mechanisms and structural details of a fundamental biological process - how a cell nucleus and its chromosomal material reorganizes itself after cell division

5 Dec 2019

New discovery may bring scientists a step closer to developing hearing loss treatments

A new discovery from a team led by Massachusetts Eye and Ear researchers may bring scientists a step closer to developing treatments that regrow the lost cells that cause hearing loss.

4 Dec 2019

SDSU researchers show cancer-inhibiting potential of flavonoid metabolite

Eating fruits and vegetables is more important than ever.

2 Dec 2019

Scientists uncover functions of mysterious organelles in stress response

Stress is a normal response to physical and emotional stimuli, particularly when people face changes in their lives. Though it’s a normal feeling, long-term stress may lead to a range of health conditions. Though people feel stressed from time to time, not all stress is bad.

1 Dec 2019

Review: Benefits, safety of fortifying wheat or maize flour with folic acid and health outcomes

Folate is an essential B-vitamin that is needed for DNA synthesis and cell division. Folate deficiency can lead to anemia, and deficiency early in pregnancy can lead to neural tube defects – birth defects of the brain, spine and spinal cord, including spina bifida.

27 Nov 2019