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CIRM awards $7.4 million to advance stem cell-based gene therapy for Friedreich's ataxia

The California Institute for Regenerative Medicine (CIRM) has awarded $7.4 million to support a University of California San Diego team developing a first-of-its-kind stem cell-based gene therapy for Friedreich's ataxia, a rare inherited neurodegenerative disease that causes progressive loss of coordination, muscle strength, heart function and overall mobility.

8 Jan 2026

Specific gut bacteria found to drive alcohol production in patients with auto-brewery syndrome

Researchers at University of California San Diego, Mass General Brigham, and their colleagues have identified specific gut bacteria and metabolic pathways that drive alcohol production in patients with auto-brewery syndrome (ABS).

8 Jan 2026

Arginine can modify plaque formation on teeth and protect against dental caries

New human clinical trial proves arginine, an amino acid, can modify plaque formation on teeth, thereby protecting against dental caries.

8 Jan 2026

Solving the home care quandary

You're ready to leave the hospital, but you don't feel able to care for yourself at home yet.

8 Jan 2026

Maternal pertussis vaccination delivers early immune protection to newborns

Vaccinating women during pregnancy leads to the transfer of antibodies to their newborns. These antibodies were detected not only in blood, but also in the nasal mucosa, the site where whooping cough bacteria enter the body.

7 Jan 2026

Single-dose oral cholera vaccine shows promising results in early clinical trial

Clinical trial shows promising results for PanChol, a single-dose oral vaccine aimed at the up to 4 million annual cholera cases worldwide.

7 Jan 2026

Web-app helps children with epilepsy to fall asleep earlier

An evidence-based web-app helped children with epilepsy to fall asleep on average 16.5 minutes earlier.

7 Jan 2026

Enveda’s third asset to the clinic with US FDA IND clearance: What it means for Inflammatory Bowel Disease

Enveda, a multi-asset clinical-stage biotech company pioneering the discovery and development of a new generation of small-molecule drugs derived from life’s chemistry, has announced that the US Food and Drug Administration (FDA) has cleared the Company’s Investigational New Drug (IND) application for ENV-6946.

From Hanson Wade Group - 4th Precision Medicine in Inflammatory Bowel Disease Summit 6 Jan 2026

The gut is not just digestive and new evidence shows it actively controls brain function

This comprehensive review synthesizes a decade of human and animal research to explain how the gut and brain communicate through hormonal, neural, immune, and microbial pathways. It highlights how disruptions in these pathways contribute to gastrointestinal, metabolic, and neurological disorders, and how modern therapies are beginning to exploit gut–brain signaling for clinical benefit.

6 Jan 2026

Restoring brain energy balance reverses advanced Alzheimer’s disease in mouse models

For over a century, Alzheimer's disease (AD) has been considered irreversible. Consequently, research has focused on disease prevention or slowing, rather than recovery.

6 Jan 2026

TAAR1 mutation impairs brain signaling in schizophrenia

A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely silence a brain receptor that pharmaceutical companies are racing to target with new drugs.

6 Jan 2026

Finger-prick blood tests enable remote detection of Alzheimer’s biomarkers

A groundbreaking international study has demonstrated that Alzheimer's disease biomarkers can be accurately detected using simple finger-prick blood samples that can be collected at home and mailed to laboratories without refrigeration or prior processing.

5 Jan 2026

New trial aims to improve both survival and quality of life for men with advanced prostate cancer

The Alliance for Clinical Trials in Oncology has launched a randomized phase III clinical trial called RECIPROCAL (Alliance A032304) to explore whether doctors can optimize the timing of targeted radiation therapy to minimize side effects while preserving efficacy in men with advanced prostate cancer.

5 Jan 2026

Progesterone mimic plus anti-estrogen treatment slows tumor growth in breast cancer patients

A drug mimicking the hormone progesterone has anti-cancer activity when used together with conventional anti-estrogen treatment for women with breast cancer, a new Cambridge-led trial has found.

5 Jan 2026

Elevated bacteria levels in tumors weaken immune response, studies show

Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.

2 Jan 2026

Simple reminder emails increase clinicians' use of database for safe opioid prescribing

A new randomized clinical trial finds that simple reminder emails substantially increase clinicians' use of a database that supports safe prescribing of opioids and other drugs, even though opioid prescribing patterns themselves did not meaningfully change during the study period.

30 Dec 2025

Trial evaluates a traditional Chinese herbal formula for diabetic kidney disease with macroalbuminuria

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Clinical Trial News and Research

CIRM awards $7.4 million to advance stem cell-based gene therapy for Friedreich's ataxia

Specific gut bacteria found to drive alcohol production in patients with auto-brewery syndrome

Arginine can modify plaque formation on teeth and protect against dental caries

Solving the home care quandary

Maternal pertussis vaccination delivers early immune protection to newborns

Single-dose oral cholera vaccine shows promising results in early clinical trial

Web-app helps children with epilepsy to fall asleep earlier

Enveda’s third asset to the clinic with US FDA IND clearance: What it means for Inflammatory Bowel Disease

The gut is not just digestive and new evidence shows it actively controls brain function

Restoring brain energy balance reverses advanced Alzheimer’s disease in mouse models

TAAR1 mutation impairs brain signaling in schizophrenia

Finger-prick blood tests enable remote detection of Alzheimer’s biomarkers

New trial aims to improve both survival and quality of life for men with advanced prostate cancer

Progesterone mimic plus anti-estrogen treatment slows tumor growth in breast cancer patients

Elevated bacteria levels in tumors weaken immune response, studies show

Simple reminder emails increase clinicians' use of database for safe opioid prescribing

Trial evaluates a traditional Chinese herbal formula for diabetic kidney disease with macroalbuminuria

Combination therapy offers hope for AML patients facing drug resistance

Study reveals a therapeutic vulnerability in aggressive subtype of triple-negative breast cancer

Restoring brain energy balance reverses Alzheimer’s disease in mouse models

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