Gene Editing News and Research

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Correcting mutations in muscle stem cells using new gene-editing technology

A new gene-editing technique can be used to correct mutations in muscle stem cells, paving the way for the first potential cell therapy for genetic muscle disorders.

30 Apr 2021

Novel integrative genetic screening platform offers insights into role of DNA accessibility in cancer

In a new resource for the scientific community, published today in Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.

30 Apr 2021

A new strain of common probiotic can potentially be more effective at protecting infant health

Researchers at the University of Helsinki have created a strain of the Lacticaseibacillus rhamnosus GG probiotic that is able to utilize both lactose and casein as well as reproduce in dairy products.

29 Apr 2021

CRISPR/Cas technology helped revolutionize diagnostics and gene therapy

Announcing a new article publication for BIO Integration journal. In this mini review article the authors Meiyu Qiu and Pei Li from Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea summarize CRISPR/Cas-based Diagnostics and Gene Therapy.

26 Apr 2021

Novel approach to gene editing bypasses disease-causing mutations in a gene

A new approach to gene editing using the CRISPR/Cas9 system bypasses disease-causing mutations in a gene, enabling treatment of genetic diseases linked to a single gene, such as cystic fibrosis, certain types of sickle cell anemia, and other rare diseases.

21 Apr 2021

Novel CRISPR-based technology may lead to powerful epigenetic therapies

Scientists have figured out how to modify CRISPR's basic architecture to extend its reach beyond the genome and into what's known as the epigenome -- proteins and small molecules that latch onto DNA and control when and where genes are switched on or off.

17 Apr 2021

Altering a mosquito's gut genes shows promise to curb malaria

Altering a mosquito's gut genes to make them spread antimalarial genes to the next generation of their species shows promise as an approach to curb malaria, suggests a preliminary study published today in eLife.

13 Apr 2021

New approach to scale up genome editing in tiny worms

Understanding the effects of specific mutations in gene regulatory regions - the sections of DNA and RNA that turn genes on and off - is important to unraveling how the genome works, as well as normal development and disease.

13 Apr 2021

Rice bioengineer wins NIH support for a new strategy to fight cystic fibrosis

Chemical and biomolecular engineer Xue Sherry Gao of Rice University's Brown School of Engineering has won National Institutes of Health support for a new strategy to fight cystic fibrosis.

8 Apr 2021

PNA-based gene editing technique can advance gene discovery

In an article published in the April 8 issue of Nature, the National Institutes of Health's Somatic Cell Gene Editing Consortium provided a detailed update on the progress of their nationwide effort to develop safer and more effective methods to edit the genomes of disease-relevant somatic cells and reduce the burden of disease caused by genetic changes.

8 Apr 2021

Single injection of RNA therapy improves vision in patient with genetic form of childhood blindness

A Penn Medicine patient with a genetic form of childhood blindness gained vision, which lasted more than a year, after receiving a single injection of an experimental RNA therapy into the eye.

1 Apr 2021

Fight for Sight funds research to explore gene editing as treatment for inherited retinal diseases

Fight for Sight is funding cutting-edge research at UCL, which will explore whether gene editing could be used to repair faults in genes for some inherited retinal diseases.

1 Apr 2021

Prime editing enables more precise correction of genetic problems than traditional CRISPR

The latest gene editing technology, prime editing, expands the "genetic toolbox" for more precisely creating disease models and correcting genetic problems, scientists say.

30 Mar 2021

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient's own blood-forming stem cells.

30 Mar 2021

New diagnostic test can detect COVID-19 virus even when it mutates

A team of scientists led by Nanyang Technological University, Singapore (NTU Singapore) has developed a diagnostic test that can detect the virus that causes COVID-19 even after it has gone through mutations.

30 Mar 2021

Researchers test novel gene regulation approach to treat brain diseases

Researchers at the DZNE (Germany), at Massachusetts General Hospital (USA) and at the genomic medicine company Sangamo Therapeutics, Inc. tested a novel gene regulation approach to treat brain diseases such as Alzheimer's in laboratory studies.

22 Mar 2021

Optimized nano-micelles can induce efficient genome editing in the mouse brain

The research group of Deputy Principal Research Scientist Dr. Satoshi Uchida (Associate Professor, Kyoto Prefectural University of Medicine) at the Innovation Center of NanoMedicine (Director General: Prof. Kazunori Kataoka, Location: Kawasaki-Japan, Abbreviation: iCONM) reported that optimized nano-micelles can induce efficient genome editing in the mouse brain.

12 Mar 2021

Optimized nano-micelles can induce efficient genome editing in the mouse brain

12 Mar 2021

Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders

A team of researchers from the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore have developed a CRISPR-based gene editor, C-to-G Base Editor (CGBE), to correct mutations that cause genetic disorders.

11 Mar 2021

Study opens the door to new possibilities targeting telomeres to help treat cancer

The Telomeres and Telomerase Group led by Maria A. Blasco at the Spanish National Cancer Research Centre continues to make progress in unraveling the role that telomeres -the ends of chromosomes that are responsible for cellular aging as they shorten- play in cancer.

10 Mar 2021

Gene Editing News and Research

Correcting mutations in muscle stem cells using new gene-editing technology

Novel integrative genetic screening platform offers insights into role of DNA accessibility in cancer

A new strain of common probiotic can potentially be more effective at protecting infant health

CRISPR/Cas technology helped revolutionize diagnostics and gene therapy

Novel approach to gene editing bypasses disease-causing mutations in a gene

Novel CRISPR-based technology may lead to powerful epigenetic therapies

Altering a mosquito's gut genes shows promise to curb malaria

New approach to scale up genome editing in tiny worms

Rice bioengineer wins NIH support for a new strategy to fight cystic fibrosis

PNA-based gene editing technique can advance gene discovery

Single injection of RNA therapy improves vision in patient with genetic form of childhood blindness

Fight for Sight funds research to explore gene editing as treatment for inherited retinal diseases

Prime editing enables more precise correction of genetic problems than traditional CRISPR

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

New diagnostic test can detect COVID-19 virus even when it mutates

Researchers test novel gene regulation approach to treat brain diseases

Optimized nano-micelles can induce efficient genome editing in the mouse brain

Optimized nano-micelles can induce efficient genome editing in the mouse brain

Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders

Study opens the door to new possibilities targeting telomeres to help treat cancer

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