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Peacemaker immune cells offer new hope for restoring immune tolerance

'Peacemaker' immune cells could help treat diseases ranging from type 1 diabetes to neurodegeneration by restoring immune tolerance, according to a new paper in Frontiers in Science.

25 Jun 2026

Transfemoral J-Valve device improves symptoms in severe aortic regurgitation patients

New research simultaneously published today in JSCAI and presented at New York Valves 2026 reported favorable one-year outcomes in patients with symptomatic severe aortic regurgitation following treatment with the investigational J-Valve Transfemoral System.

25 Jun 2026

Study identifies fPRDM16 as target for age-related pulmonary fibrosis

A study published recently in Current Molecular Pharmacology has uncovered a key mechanism linking aging to persistent pulmonary fibrosis, identifying the transcriptional regulator fPRDM16 as a potential therapeutic target.

25 Jun 2026

AI-driven approach identifies promising new target for CAR T cell therapy

Leading CAR T cell therapy researchers have developed a human-in-the-loop artificial intelligence (AI) framework that firmly centers scientists' expertise to find viable target antigens for CAR T cell therapy.

25 Jun 2026

Study identifies key fibrotic cells driving hypertrophic scars

Hypertrophic scars (HS) are abnormal outcomes of wound healing, marked by excessive extracellular matrix (ECM) deposition and impaired scar remodeling.

25 Jun 2026

Bariatric surgery linked to higher risk of developing alcohol problems

Your body absorbs alcohol much more rapidly after bariatric surgery. Patients need to know this when they choose the kind of surgery they will have.

25 Jun 2026

European project receives €15 million to study phage-based therapies

Bacteria are becoming increasingly resistant to antibiotics. One alternative is treatment with viruses that exclusively infect bacteria, known as phages.

25 Jun 2026

US study shows updated COVID vaccines cut hospitalization odds by 55%

The 2025-2026 COVID-19 vaccines were associated with 50% estimated effectiveness against COVID-19-associated emergency department and urgent care encounters among immunocompetent US adults. They were also linked to an estimated 55% effectiveness against COVID-19-associated hospitalization, providing added protection beyond existing immunity from prior infection or vaccination.

24 Jun 2026

Immune cells drive abnormal joint tissue growth in rheumatoid arthritis

Researchers at Hospital for Special Surgery (HSS) have identified a specialized population of immune cells that play a central role in driving abnormal tissue growth in rheumatoid arthritis (RA), offering new insight into disease progression and potential treatment strategies.

24 Jun 2026

Genetic testing could sharply increase demand for ALS specialist care

The availability of genetic testing for amyotrophic lateral sclerosis (ALS) for people with a family member diagnosed with the disease is expected to greatly increase the number of clinic visits to specialized ALS centers over the next decade, according to a study published June 24, 2026, in Neurology Genetics, an official journal of the American Academy of Neurology.

24 Jun 2026

New oral drug shows promise for chronic heart failure treatment

An early clinical study shows that a new oral drug is safe and well-tolerated in patients with chronic heart failure.

24 Jun 2026

Concerns about weight regain after yo‑yo dieting are largely unfounded, review shows

Many people experience fluctuations in body weight throughout their lives, and so‑called yo‑yo dieting has long been considered a health risk – in some cases even more harmful than remaining overweight.

24 Jun 2026

Immunotherapy may help women with early ovarian insufficiency to conceive babies

A pilot study from Karolinska Institutet shows that immunotherapy may enable stimulation of egg maturation in women with autoimmune POI (premature ovarian insufficiency) – a condition that usually leads to infertility.

24 Jun 2026

Modulating pathogenic scar cells promotes spinal cord regeneration

SCI often causes long-term motor and sensory deficits because the damaged tissue does not simply heal like many peripheral tissues.

24 Jun 2026

Scientists identify genes linking air pollution to severe asthma

For many people with asthma, air-quality advisories are harbingers of worsening symptoms. But for reasons science has struggled to explain, the extent to which pollution exacerbates asthma varies widely from person to person.

24 Jun 2026

Open source tool automates data reanalysis to detect rare diseases

A newly developed open-source tool designed for rigorous reanalysis of genomic data is highly effective at detecting new rare disease diagnoses.

24 Jun 2026

Review outlines key strategies to overcome antibody drug conjugate resistance

The first Antibody-drug conjugate (ADC) was approved overa quarter-century ago, and today more than 20 have reached the clinic.

24 Jun 2026

Duke researchers discover molecules that target vital cell signaling proteins

To function normally, nearly every cell in the human body relies on G-protein coupled receptors (GPCRs) to receive and send signals. That's why GPCRs are targeted by roughly one-third of all FDA‑approved drugs.

24 Jun 2026

Microbes trigger cell death to boost cancer immunotherapy effectiveness

Traditional cancer treatments like chemotherapy and radiotherapy can induce immunogenic cell death (ICD), but their efficacy is often limited by drug resistance, severe off-target toxicity, and immune-related adverse events.

24 Jun 2026