Paralysis News and Research

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Paralysis is the loss of muscle function in part of your body. It happens when something goes wrong with the way messages pass between your brain and muscles. Paralysis can be complete or partial. It can occur on one or both sides of your body. It can also occur in just one area, or it can be widespread. Paralysis of the lower half of your body, including both legs, is called paraplegia. Paralysis of the arms and legs is quadriplegia.

Cancer risk found to be three times greater after acute thrombosis in the leg

Patients with the most acute type of thrombosis in the leg - known as an arterial thrombosis - risk developing diseases that are far worse than the blood clot itself. The risk of developing cancer during the first six months after the blood clot is three times greater than normal.

16 Apr 2018

Deficiency of innate immune adaptor TRIF shortens survival time of ALS mice

Amyotrophic lateral sclerosis is a neurodegenerative disease damaging motor neurons in brain and spinal cords. ALS patients show progressive muscle weakness and atrophy, leading to a fatal respiratory muscle paralysis. There are no effective therapies for ALS.

16 Apr 2018

Japanese researchers develop new compound to enhance recovery of stroke patients

A team of Japanese researchers have developed a new compound that enhanced motor function recovery after brain damage in animal tests, according to a study published in the journal Science.

10 Apr 2018

Hottest pepper gives man “thunderclap”

An unidentified 34 year old man reportedly ate a Carolina Reaper – one of the hottest rates peppers in the world, during a contest. What followed was a series of intense headaches and retching in the man. The headaches are typically termed 'thunderclap headaches'. The case study was published this week by the doctors attending the man in the journal BMJ Case Reports.

10 Apr 2018

New point-of-care test accelerates diagnosis of Lyme neuroborreliosis

A new research-based point-of-care test has been developed in Finland for detecting the Lyme neuroborreliosis spread by ticks.

5 Apr 2018

FDA-approved drug for chemical abortion shows promise for treatment of vestibular schwannoma

Massachusetts Eye and Ear researchers have shown that mifepristone, a drug currently FDA-approved for chemical abortion, prevents the growth of vestibular schwannoma cells. This sometimes-lethal intracranial tumor typically causes hearing loss and tinnitus

3 Apr 2018

Study identifies potential genetic link in sudden infant death syndrome

Rare genetic mutations associated with impairment of the breathing muscles are more common in children who have died from sudden infant death syndrome (also known as ‘cot death’) than in healthy controls, suggesting a possible genetic element of the disorder, according to a case-control study in the UK and USA published in The Lancet.

29 Mar 2018

Specific immune cells may help slow progression of ALS, research shows

New research into Amyotrophic Lateral Sclerosis (ALS) - also known as motor neuron disease - shows that specific immune cells may help slow progression of the disease, an important step towards developing new therapies to treat patients.

22 Mar 2018

Discovery of new ALS gene points to cytoskeleton as potential target for drug development

An international team of researchers led by John Landers, PhD, at UMass Medical School, and Bryan Traynor, MD, PhD, at the National Institute on Aging at the National Institutes of Health, has identified KIF5A as a new gene associated with the development of amyotrophic lateral sclerosis.

21 Mar 2018

Scientists discover basic molecular mechanism that helps understand how ALS works

It took eight long years of research, but now an international team led by neuroscientists at Université de Montréal has discovered a basic molecular mechanism that better helps understand how Lou Gehrig's disease, or amyotrophic lateral sclerosis (ALS), works.

19 Mar 2018

Epidural stimulation can safely, effectively normalize blood pressure in patients with SCI

Patients with severe spinal cord injury (SCI) often experience chronically low blood pressure that negatively affects their health, their quality of life and their ability to engage in rehabilitative therapy.

19 Mar 2018

Discovery aids understanding of amyotrophic lateral sclerosis

Researchers have discovered a basic molecular mechanism that sheds light on the disease process underlying amyotrophic lateral sclerosis (ALS).

19 Mar 2018

Clinical trial to test efficacy of stem cell transplants in stopping ALS muscle deterioration

Once funding is obtained, researchers can perform a clinical trial to test the efficacy of transplanting bone marrow cells into muscles to stop deterioration caused by the illness. The method has already yielded positive results on mice.

16 Mar 2018

NIH-funded researchers use CRISPR to rapidly find new genetic suspects behind ALS, FTD

NIH-funded researchers at Stanford University used the gene editing tool CRISPR-Cas9 to rapidly identify genes in the human genome that might modify the severity of amyotrophic lateral sclerosis and frontotemporal dementia caused by mutations in a gene called C9orf72.

13 Mar 2018

Bowel care ranks top concern for individuals with spinal cord injury, study shows

Cardiovascular physiology researcher Victoria Claydon's latest study, published in the Journal of Neurotrauma, focuses on the results of her multi-national study, which surveyed almost 300 participants with spinal cord injuries at or above the mid-thoracic level (middle of the chest ).

9 Mar 2018

Research reveals neuroprotective mechanisms of gene and cell medications for spinal cord injuries

A joint paper with Kazan State Medical University appeared in Stem Cells International. The research was based at the Gene and Cell Technologies Lab of Kazan University.

8 Mar 2018

Study sheds light on neuronal responses in ALS

In a recent study, scientists have linked changes in the size of motor neurons to the onset of symptoms in motor neurone disease (ALS).

5 Mar 2018

Young men recovering from flu have increased risk of developing Guillain-Barré syndrome

This year's flu season has been one of the worst in recent memory causing thousands of people to be hospitalized. The virus can be particularly dangerous for young men who can experience nerve damage caused by the body's response to the flu.

2 Mar 2018

New treatment shows promise to fight against serious inflammatory disease

Still's disease is a serious orphan disease manifested by high fevers, skin and joint involvement, including paralysis, as well as damage to other organs such as the liver or spleen. It is caused by a deregulation of the immune system triggering an acute inflammatory response.

27 Feb 2018

Study finds novel therapeutic strategy that preserves neuromuscular synapses in ALS mouse model

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, causes lethal respiratory paralysis within several years of diagnosis. There are no effective treatments to slow or halt this devastating disease.

21 Feb 2018

Paralysis News and Research

Further Reading

Cancer risk found to be three times greater after acute thrombosis in the leg

Deficiency of innate immune adaptor TRIF shortens survival time of ALS mice

Japanese researchers develop new compound to enhance recovery of stroke patients

Hottest pepper gives man “thunderclap”

New point-of-care test accelerates diagnosis of Lyme neuroborreliosis

FDA-approved drug for chemical abortion shows promise for treatment of vestibular schwannoma

Study identifies potential genetic link in sudden infant death syndrome

Specific immune cells may help slow progression of ALS, research shows

Discovery of new ALS gene points to cytoskeleton as potential target for drug development

Scientists discover basic molecular mechanism that helps understand how ALS works

Epidural stimulation can safely, effectively normalize blood pressure in patients with SCI

Discovery aids understanding of amyotrophic lateral sclerosis

Clinical trial to test efficacy of stem cell transplants in stopping ALS muscle deterioration

NIH-funded researchers use CRISPR to rapidly find new genetic suspects behind ALS, FTD

Bowel care ranks top concern for individuals with spinal cord injury, study shows

Research reveals neuroprotective mechanisms of gene and cell medications for spinal cord injuries

Study sheds light on neuronal responses in ALS

Young men recovering from flu have increased risk of developing Guillain-Barré syndrome

New treatment shows promise to fight against serious inflammatory disease

Study finds novel therapeutic strategy that preserves neuromuscular synapses in ALS mouse model

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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