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Study reveals how M. tuberculosis escapes death in macrophages

The bacteria that cause the devastating disease tuberculosis have the ability to escape destruction and grow after they are engulfed by lung macrophages, the immune cells that are supposed to destroy pathogens.

10 Jul 2018

Researchers use genome editing to reduce cholesterol levels in animal model

Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey, according to researchers from the Perelman School of Medicine at the University of Pennsylvania.

10 Jul 2018

Researchers discover mechanism that shuts down cell-to-cell communications pathway

Cellular functions rely on several communications networks that allow cells to rapidly respond to signals affecting the organism.

10 Jul 2018

Certain antibodies against a carbohydrate could protect against malaria

Certain type of antibodies against α-Gal- a carbohydrate expressed by many organisms including the malaria parasite- could protect against malaria, according to a new study led by ISGlobal, an institution supported by "la Caixa" Foundation.

10 Jul 2018

Novel plasmonic patch increases brightness in diagnostic tests

Fluorescence-based biosensing and bioimaging technologies are widely used in research and clinical settings to detect and image various biological species of interest.

10 Jul 2018

Altitude sickness drug may offer significant gains for patients with glioblastoma

A drug used to treat altitude sickness -- as well as glaucoma, epilepsy, heart failure and seizures -- may also offer significant gains for patients with a fast-growing brain tumor known as glioblastoma, according to a study published July 4, 2018, in the journal Science Translational Medicine.

10 Jul 2018

Researchers use x-ray crystallography to reveal how curcumin inhibits cancer

Through x-ray crystallography and kinase-inhibitor specificity profiling, University of California San Diego School of Medicine researchers, in collaboration with researchers at Peking University and Zhejiang University, reveal that curcumin, a natural occurring chemical compound found in the spice turmeric, binds to the kinase enzyme dual-specificity tyrosine-regulated kinase 2 at the atomic level.

10 Jul 2018

Scientists discover new target to treat blood vessel damage in diabetes

In diabetes, both the tightly woven endothelial cells that line our blood vessels and the powerhouses that drive those cells start to come apart as early steps in the destruction of our vasculature.

9 Jul 2018

UT Southwestern researchers uncover body's microreactors for innate immunity

A DNA-sensing enzyme forms droplets that act as tiny bioreactors creating molecules to stimulate innate immunity – the body's first response to infection, UT Southwestern researchers report. The work, reported today in the journal Science, could lead to novel treatments for infections, autoimmune disease, and cancer.

9 Jul 2018

Bacteria adapted to the human body may become more susceptible to antibiotics

A new study published today in Nature Communications, led by scientists at the University of Liverpool in collaboration with the University of Salford, finds evidence that as bacteria adapt to the human body, they can sometimes become more susceptible to antibiotics and therefore easier to kill.

6 Jul 2018

Survival mechanisms of polar fish inspire revolutionary method to 'freeze' bacteria

The survival mechanisms of polar fish have led scientists at the University of Warwick to develop of a revolutionary approach to 'freeze' bacteria.

6 Jul 2018

Scientists synthesize new compound with anticarcinogenic properties

The patent has been registered from the University of Seville and licensed by the British company Evgen Pharma, which is currently developing programmes aimed at breast cancer, subarachnoid haemorrhage and multiple sclerosis, among others

5 Jul 2018

Scientists develop new understanding of how psychiatric diseases manifest and can be treated

Research scientists from The Feinstein Institute for Medical Research and the Donald and Barbara Zucker School of Medicine at Hofstra/Northwell in Hempstead, NY, in conjunction with their colleagues at Rockefeller University in New York City, have developed a new understanding of how certain psychiatric diseases - those that involve uncontrollable reactions to stimuli such as the high and low experiences attributed to bi-polar disorder, the impulsivity of an individual suffering from attention deficit hyperactivity disorder, and even suicidality - manifest and potentially can be treated. These findings were published today in Proceedings of the National Academy of Sciences.

3 Jul 2018

Compounds found in green tea and red wine offer hope to treat inborn congenital metabolic diseases

A new Tel Aviv University study suggests there is hope of treating certain inborn congenital metabolic diseases -- a hope found in green tea and in red wine.

2 Jul 2018

Established lung fibrosis can be reversed using diabetes drug treatment

Researchers at the University of Alabama at Birmingham have shown - for the first time - that established lung fibrosis can be reversed using a drug treatment that targets cell metabolism.

2 Jul 2018

New Rekovelle analysis shows AMH is robust predictor of ovarian response to fertility treatment

Ferring Pharmaceuticals announced today a new analysis of data from the Phase 3 ESTHER-1 trial showing that natural variations in anti-Müllerian hormone levels during and between a woman's menstrual cycle have no clinically relevant impact on ovarian response when using AMH to dose Rekovelle for ovarian stimulation.

2 Jul 2018