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The impact of COVID-19 on people with systemic autoimmune rheumatic diseases

A survey demonstrated that patients with systemic autoimmune rheumatic diseases commonly experience augmented disease severity and disrupted treatment regimens of disease-modifying antirheumatic drugs after acute COVID-19 course.

11 Feb 2022

New tools may better help in prevention of heart disease in individuals with chronic kidney disease

A new study reveals that certain changes to models that predict the risk of developing cardiovascular problems in the general population can help clinicians improve risk prediction in individuals with kidney disease.

11 Feb 2022

Yale researchers confirm the health benefits of moderate calorie restrictions in humans

Decades of research has shown that limits on calorie intake by flies, worms, and mice can enhance life span in laboratory conditions. But whether such calorie restriction can do the same for humans remains unclear.

11 Feb 2022

Deactivation of PLa2g7 gene mimics anti-aging effects of caloric restriction in mice

Deactivation of the gene PLa2g7 partially mimics the anti-aging effects of caloric restriction (CR) in mice, researchers report.

11 Feb 2022

Scientists discover a new class of potential drug targets for neurodegenerative diseases

Oregon State University scientists have discovered a new class of potential drug targets for people suffering from neurodegenerative conditions such as Alzheimer's, Parkinson's and Lou Gehrig's disease.

10 Feb 2022

New protocol for transplanting 3D cellular structures to regenerate damaged intestinal tissue

Ulcerative colitis is an inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in the digestive tract. Ulcerative colitis affects the innermost lining of the colon and rectum.

10 Feb 2022

Potential new diagnostic marker for ulcerative colitis discovered

An international research collaboration has discovered a potential new diagnostic marker for ulcerative colitis in a trans-ethnic analysis of Japanese and white patients.

10 Feb 2022

Scientists identify multi-kinase inhibitors that can effectively block SARS-CoV-2-mediated cytokine release

Researchers investigated the efficacy of two multi-kinase inhibitors, olverembatinib and ponatinib, in inhibiting SARS-CoV-2 omicron-mediated cytokine release in human peripheral blood mononuclear cells.

10 Feb 2022

Protective efficacy of BNT162b2 and Ad26.COV2.S against SARS-CoV-2 Omicron challenge in nonhuman primates

The study highlights the significance of mix-and-match vaccine regimens to diversify the immune responses against highly mutated variants of SARS-CoV-2 such as Omicron.

10 Feb 2022

Omicron resists antibodies, causes less severe disease than previous SARS-CoV-2variants

In two recent studies, researchers at Washington University School of Medicine in St. Louis found evidence that the omicron variant of the virus that causes COVID-19 causes less severe disease than previous variants — at least in rodents — but that many antibody-based therapies may not be effective against it.

10 Feb 2022

Researchers identify a potent new combination of antiviral drugs to combat SARS-CoV-2

The recent success of Paxlovid has encouraged researchers to develop new anti-covid drugs. With this in mind, scientists from the University of Pennsylvania have been investigating a new synergistic treatment. Their research is released early as an unedited version of the manuscript to be published in the journal Nature.

9 Feb 2022

Persistent Ebola virus can hide in the brain and re-emerge to cause fatal disease

In a groundbreaking study published today, scientists describe how Ebola virus, which can persist in certain areas of the body, can re-emerge to cause fatal disease - even long after treatment with monoclonal antibodies.

9 Feb 2022

Research lays the groundwork to better understand and treat Crohn's disease

A paper published this week in Immunity, a leading research journal highlighting discoveries in immunology by Cell Press, lays the groundwork to better understand and treat Crohn's disease, a type of Inflammatory Bowel Disease (IBD).

9 Feb 2022

Research may lead to the development of effective fasting-based therapies

Voluntary fasting, for example interval fasting, is beneficial to health for many people, depending on their individual condition. For example, controlled periods of starvation can prevent and improve diseases such as diabetes and obesity.

9 Feb 2022

Philippines starts vaccinating children aged five to 11 against COVID-19

The Philippines began vaccinating children aged five to 11 against COVID-19 on Monday after initial hiccups over delayed deliveries of the Pfizer-BioNTech doses and opposition to the drive by some parents.

9 Feb 2022

Single-cell sequencing provides detailed insight into early SARS-CoV-2 infection in the lungs

What is going on at the single-cell level in the first days of SARS-CoV-2 infection in the lungs?

9 Feb 2022

Research findings provide a potential roadmap for metastatic tumor formation

Using data from over 100,000 malignant and non-malignant cells from 15 human brain metastases, UCSF researchers have revealed two functional archetypes of metastatic cells across 7 different types of brain tumors, each containing both immune and non-immune cell types.

9 Feb 2022

Innate immune specificity is driven by the nervous system, study suggests

Research led by Washington State University scientists supports a novel theory that the innate immune system people are born with can respond differently to specific pathogens.

9 Feb 2022

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

In a new study, researchers revealed that the nucleotide-binding oligomerization domain-like receptors or NOD-like receptors family pyrin domain containing 3 (NLRP3) inflammasome is activated by the exosomes from plasma in COVID-19.

9 Feb 2022

Study finds 50% increase in hospitalizations for alcoholic hepatitis in early months of the pandemic

In new research published in Liver International, researchers at Henry Ford Health System have found that people hospitalized for alcoholic hepatitis – a life threatening liver disease fueled by alcohol use – increased a staggering 50 percent in the early months of the COVID-19 pandemic.

9 Feb 2022

Inflammation News and Research

The impact of COVID-19 on people with systemic autoimmune rheumatic diseases

New tools may better help in prevention of heart disease in individuals with chronic kidney disease

Yale researchers confirm the health benefits of moderate calorie restrictions in humans

Deactivation of PLa2g7 gene mimics anti-aging effects of caloric restriction in mice

Scientists discover a new class of potential drug targets for neurodegenerative diseases

New protocol for transplanting 3D cellular structures to regenerate damaged intestinal tissue

Potential new diagnostic marker for ulcerative colitis discovered

Scientists identify multi-kinase inhibitors that can effectively block SARS-CoV-2-mediated cytokine release

Protective efficacy of BNT162b2 and Ad26.COV2.S against SARS-CoV-2 Omicron challenge in nonhuman primates

Omicron resists antibodies, causes less severe disease than previous SARS-CoV-2variants

Researchers identify a potent new combination of antiviral drugs to combat SARS-CoV-2

Persistent Ebola virus can hide in the brain and re-emerge to cause fatal disease

Research lays the groundwork to better understand and treat Crohn's disease

Research may lead to the development of effective fasting-based therapies

Philippines starts vaccinating children aged five to 11 against COVID-19

Single-cell sequencing provides detailed insight into early SARS-CoV-2 infection in the lungs

Research findings provide a potential roadmap for metastatic tumor formation

Innate immune specificity is driven by the nervous system, study suggests

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

Study finds 50% increase in hospitalizations for alcoholic hepatitis in early months of the pandemic

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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