immunity News and Research

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Transcriptional scanning in the sperm may regulate rate of human evolution

Maturing sperm cells turn on most of their genes, not to follow their genetic instructions like normal, but instead to repair DNA before passing it to the next generation, a new study finds.

23 Jan 2020

Study findings have implications for meningococcal B vaccine programs globally

The results of the B Part of It study – the largest meningococcal B herd immunity study ever conducted – are published today in the New England Journal of Medicine.

22 Jan 2020

Study shows how gene therapy may help protect against vision loss in multiple sclerosis

New research by Dorothy P. Schafer, PhD, at the University of Massachusetts Medical School, reveals the molecular process in which synaptic connections in the brain are damaged in multiple sclerosis and how this contributes to neurodegenerative symptoms.

21 Jan 2020

Lung microbiome of critically ill patients is predictive of clinical outcomes

Changes in the lung microbiome may help predict how well critically ill patients will respond to care, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

21 Jan 2020

Patient-specific tumor organoids may one day be used to personalize cancer treatment

A patient-specific tumor organoid platform developed by Wake Forest Institute for Regenerative Medicine researchers and their cancer center colleagues could someday take the guessing game out of immunotherapy treatments.

21 Jan 2020

Discovery of new killer T-cell offers hope of a 'one-size-fits-all' cancer therapy

Researchers at Cardiff University have discovered a new type of killer T-cell that offers hope of a "one-size-fits-all" cancer therapy.

21 Jan 2020

Breakthrough discovery could lead to more effective immunotherapies

Scientists at UCL have discovered how immune cells, essential for tackling life-threatening infections and cancers, are able to 'recycle' material within themselves in order to stay healthy and function, a breakthrough finding which could lead to more effective immunotherapies.

21 Jan 2020

UT Southwestern study identifies new vulnerability in kidney tumors

A UT Southwestern researcher led a team that identified a new vulnerability in kidney tumors, the 10th most common cause of cancer death in men and women.

17 Jan 2020

Genetically engineered mosquitoes halt Dengue spread

A new study published in the journal PLOS Pathogens in January 2020 reports the development of mosquitoes that have been genetically modified to resist infection by several types of the dengue virus. This is the first time ever that all types of the virus have been targeted by the engineering of the mosquito DNA. Covering all virus types is essential to achieve proper disease control.

16 Jan 2020

Sepsis killing more people than earlier thought

According to a new study published in the latest issue of The Lancet, this week, more people across the globe are dying of sepsis than earlier believed. A team from the University of Pittsburgh and University of Washington schools of medicine led the research along with their colleagues from different disciplines.

16 Jan 2020

New whooping cough vaccine needed to protect from emerging superbug strains

Australia needs a new whooping cough vaccine to ensure our most vulnerable are protected from the emergence of superbug strains, new UNSW research has shown.

16 Jan 2020

B cell count tells how certain cancers will respond to immunotherapy

Some melanomas, sarcomas and renal cell carcinomas, but not all, have been found to respond dramatically to new drugs called immune checkpoint blockers, which exploit the body’s known capability to mount an immune response against the foreign antigen-bearing tumor cells.

15 Jan 2020

Miracle probiotics? Take claims with a pinch of salt, says study

A new study published in the journal Frontiers in Medicine cautions the public against believing and acting on information on probiotics online because most of the websites offering such information are not dependable and their sources are dubious

15 Jan 2020

Biomaterial-based vaccine has potential to completely eliminate AML cells

Acute myeloid leukemia (AML) is a deadly blood cancer that originates in the bone marrow and kills most of its victims within five years. Chemotherapy has been the standard AML treatment for over 40 years, and while it often causes the cancer to go into remission, it rarely completely eliminates the cancerous cells, which then lead to disease recurrence in nearly half of treated patients.

14 Jan 2020

Study provides insights into how viral infection can continue to affect immunity

The strength of the immune system in response to respiratory infections is constantly changing, depending on the history of previous, unrelated infections, according to new research from the Crick.

From The Francis Crick Institute 14 Jan 2020

Researchers discover how a new immune system works to protect bacteria from phages

Researchers at University of California San Diego School of Medicine have discovered how a new immune system works to protect bacteria from bacteriophages (phages), viruses that specifically infect bacteria.

11 Jan 2020

Researchers analyze molecular characteristics of cerebrospinal fluid from LMM patients

Patients with advanced melanoma who develop metastases in the leptomeninges, the fluid filled membranes surrounding the brain and spinal cord, have an extremely dismal prognosis. Most patients only survive for 8 to 10 weeks after diagnosis.

11 Jan 2020

Siah2 Gene Control could Help Treat Melanomas More Effectively

To develop improved cancer immunotherapies, it is essential to understand how cancers shut down the natural immune response to foreign antigens. This current study demonstrates how mice lacking the Siah2 gene, fail to develop BRAF-mutation carrying melanoma from the corresponding cells, completely rejecting them. This could help in boosting the anticancer effect of existing specific immune checkpoint inhibitors, such as anti-PD-1 drugs.

10 Jan 2020

Sodium chloride nanoparticles offer potential for cancer therapies with fewer side effects

A new study at the University of Georgia has found a way to attack cancer cells that is potentially less harmful to the patient. Sodium chloride nanoparticles – more commonly known as salt – are toxic to cancer cells and offer the potential for therapies that have fewer negative side effects than current treatments.

9 Jan 2020

Nano-sized copper compounds together with immunotherapy can kill cancer cells

An interdisciplinary team of scientists from KU Leuven, the University of Bremen, the Leibniz Institute of Materials Engineering, and the University of Ioannina has succeeded in killing tumour cells in mice using nano-sized copper compounds together with immunotherapy. After the therapy, the cancer did not return.

9 Jan 2020

immunity News and Research

Transcriptional scanning in the sperm may regulate rate of human evolution

Study findings have implications for meningococcal B vaccine programs globally

Study shows how gene therapy may help protect against vision loss in multiple sclerosis

Lung microbiome of critically ill patients is predictive of clinical outcomes

Patient-specific tumor organoids may one day be used to personalize cancer treatment

Discovery of new killer T-cell offers hope of a 'one-size-fits-all' cancer therapy

Breakthrough discovery could lead to more effective immunotherapies

UT Southwestern study identifies new vulnerability in kidney tumors

Genetically engineered mosquitoes halt Dengue spread

Sepsis killing more people than earlier thought

New whooping cough vaccine needed to protect from emerging superbug strains

B cell count tells how certain cancers will respond to immunotherapy

Miracle probiotics? Take claims with a pinch of salt, says study

Biomaterial-based vaccine has potential to completely eliminate AML cells

Study provides insights into how viral infection can continue to affect immunity

Researchers discover how a new immune system works to protect bacteria from phages

Researchers analyze molecular characteristics of cerebrospinal fluid from LMM patients

Siah2 Gene Control could Help Treat Melanomas More Effectively

Sodium chloride nanoparticles offer potential for cancer therapies with fewer side effects

Nano-sized copper compounds together with immunotherapy can kill cancer cells

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