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Study finds byproduct of common prostate cancer drug can stimulate growth of tumor cells

A genetic anomaly in certain men with prostate cancer may impact their response to common drugs used to treat the disease, according to new research at Cleveland Clinic. The findings may provide important information for identifying which patients potentially fare better when treated with an alternate therapy.

26 Jun 2018

Researchers examine new influenza drug's mode of action in detail

The new influenza drug Xofluza, developed by the Japanese pharmaceutical company Shionogi, was approved for clinical use in Japan in February 2018.

26 Jun 2018

Microbiologists and plant scientists pinpoint genetic weakness in cholera pandemic's armor

While cholera rages across many regions of the world, a team of microbiologists and plant scientists has pinpointed a genetic weakness in the pandemic's armor, which could lead to future treatments.

26 Jun 2018

Novel smart probe may improve post-surgical outcomes for cancer patients

A new Tel Aviv University study explores a novel smart probe for image-guided surgery that may dramatically improve post-surgical outcomes for cancer patients.

26 Jun 2018

CRISPR technique reduces repetitive behavior in fragile X syndrome mouse models

Scientists have used CRISPR-Cas9 gene editing to lessen some autism symptoms in mice with a form of fragile X syndrome, the most common known single-gene cause of autism spectrum disorder.

25 Jun 2018

New discovery suggests potential target for treating cancers and other diseases

When cells grow and divide to ensure a biological function - such as a properly working organ - DNA must be unwound from its typical tightly packed form and copied into RNA to create proteins.

25 Jun 2018

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

Researchers use gene editing to reduce autism symptoms in mice

Researchers have used CRISPR-Cas9 gene editing to treat symptoms of autism in mice. It is hoped that the tool could one day be used to help humans.

25 Jun 2018

Scientists discover secret to success of antiviral gene

It's been known for years that humans and other mammals possess an antiviral gene called RSAD2 that prevents a remarkable range of viruses from multiplying.

25 Jun 2018

Researchers develop low-cost plastic sensors to monitor wide range of health conditions

An international team of researchers have developed a low-cost sensor made from semiconducting plastic that can be used to diagnose or monitor a wide range of health conditions, such as surgical complications or neurodegenerative diseases.

22 Jun 2018

Study suggests proteinuria lowering as important target in managing pediatric CKD

In a study of children with chronic kidney disease, blood pressure medications reduced protein excretion in the urine, which was linked with a lower risk of disease progression.

22 Jun 2018

Chemists find new way to make enzymes do a non-natural reaction

Princeton chemists have found a way to make a naturally occurring enzyme take on a new, artificial role, which has significant implications for modern chemistry, including pharmaceutical production.

22 Jun 2018

Lipid-scrambling DNA enzyme outperforms naturally occurring counterpart, say researchers

A new synthetic enzyme, crafted from DNA rather than protein, flips lipid molecules within the cell membrane, triggering a signal pathway that could be harnessed to induce cell death in cancer cells.

22 Jun 2018

Jumping genes or transposons and their role in the genetic code

Researchers have found that there a numerous transposons or “jumping genes” within the genetic code that is responsible for development of the embryo and its growth. These were earlier thought to be junk or useless parts of the genome.

22 Jun 2018

Study reveals new target to halt tumor growth

Researchers at the University of Wisconsin-Madison have discovered that a protein called Munc13-4 helps cancer cells secrete large numbers of exosomes - tiny, membrane-bound packages containing proteins and RNAs that stimulate tumor progression.

21 Jun 2018

USC study reveals how the cell launches emergency response to repair damaged DNA

The cell has its own paramedic team and emergency room to aid and repair damaged DNA, a new USC Dornsife study reveals.

21 Jun 2018

New therapeutic approach may delay neurodegeneration in rare genetic disease

A new therapeutic approach may one day delay neurodegeneration typical of a disease called mucopolysaccharidoses IIIB. Neurodegeneration in this condition results from the abnormal accumulation of essential cellular molecules called mucopolysaccharides.

21 Jun 2018

Coconut oil diet increases vitality, lifespan of fruit flies with peroxisomal disorder

"Lorenzo's Oil" was to help a seriously ill boy suffering from a peroxisomal disorder (adrenoleukodystrophy/ALD). The true story was turned into a film which made the rare disease well known. Scientists from the University of Bonn, the German Center for Neurodegenerative Diseases and the German Cancer Research Center investigated such peroxisomal diseases on fruit flies.

20 Jun 2018

Study: Long-term estrogen therapy alters microbial composition and activity in the gut

Long-term therapy with estrogen and bazedoxifene alters the microbial composition and activity in the gut, affecting how estrogen is metabolized, a new study in mice found.

20 Jun 2018

Study shows how moderate consumption of alcohol can protect the heart

For at least 20 years, research has shown that for many people, moderate consumption of alcohol can protect the heart, but the reason for this is poorly understood.

18 Jun 2018

Enzyme News and Research

Study finds byproduct of common prostate cancer drug can stimulate growth of tumor cells

Researchers examine new influenza drug's mode of action in detail

Microbiologists and plant scientists pinpoint genetic weakness in cholera pandemic's armor

Novel smart probe may improve post-surgical outcomes for cancer patients

CRISPR technique reduces repetitive behavior in fragile X syndrome mouse models

New discovery suggests potential target for treating cancers and other diseases

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Researchers use gene editing to reduce autism symptoms in mice

Scientists discover secret to success of antiviral gene

Researchers develop low-cost plastic sensors to monitor wide range of health conditions

Study suggests proteinuria lowering as important target in managing pediatric CKD

Chemists find new way to make enzymes do a non-natural reaction

Lipid-scrambling DNA enzyme outperforms naturally occurring counterpart, say researchers

Jumping genes or transposons and their role in the genetic code

Study reveals new target to halt tumor growth

USC study reveals how the cell launches emergency response to repair damaged DNA

New therapeutic approach may delay neurodegeneration in rare genetic disease

Coconut oil diet increases vitality, lifespan of fruit flies with peroxisomal disorder

Study: Long-term estrogen therapy alters microbial composition and activity in the gut

Study shows how moderate consumption of alcohol can protect the heart

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