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Researchers discover new defense mechanism against oxygen radicals

Oxygen radicals occur as a by-product when living beings burn carbohydrates or fat. They are suspected of accelerating the ageing process in humans and animals, and to be partly responsible for severe illnesses such as Alzheimer's or certain types of cancer.

18 Jun 2018

Study demonstrates increased levels of gum disease in people at risk of rheumatoid arthritis

The results of a study presented at the Annual European Congress of Rheumatology demonstrates increased levels of gum disease, and disease-causing bacteria, in individuals at risk of rheumatoid arthritis.

18 Jun 2018

Researchers find enzyme responsible for aircraft noise-related vascular damage

In a recent study, scientists at the Department of Cardiology at the University Medical Center of Johannes Gutenberg University Mainz have identified an enzyme responsible for aircraft-related vascular damage.

14 Jun 2018

Metabolic process providing energy to heart muscle fails to mature in babies with hypertrophy

A metabolic process that provides heart muscle with energy fails to mature in newborns with thickened heart walls, according to a Japan-Canada research team.

14 Jun 2018

Scientists develop method to determine metabolic activity of neural networks

During the last decade, neurobiologists's attention has been focused on the study of the functioning of neural networks rather than single nerve cells.

14 Jun 2018

New discovery could have significant implications in brain aging and cancers

Scientists at the University of Sheffield have discovered what keeps the perfect balance of breaks and repairs in our DNA - something which could help improve the success of chemotherapy and combat neurodegeneration associated with aging.

13 Jun 2018

Researchers discover unique process of brain cell death in MS

Researchers at the University of Alberta have discovered a unique process of brain cell death that affects the cells that are most vulnerable in multiple sclerosis.

13 Jun 2018

Study shows how amyloid aggregates alter brain cells in Alzheimer’s disease

A new study has revealed the mechanism through which amyloid peptide aggregates alter brain cells to cause the harmful effects seen in Alzheimer’s disease.

12 Jun 2018

TU Graz researchers manipulate enzymes to build ring-shaped molecular structures

TU Graz researchers managed for the first time ever to 'retrain' an enzyme to build ring-shaped molecular structures instead of performing its natural task of reducing double bonds.

12 Jun 2018

Penn research team identifies novel therapeutic target for heart disease

Changes in cellular struts called microtubules (MT) can affect the stiffness of diseased human heart muscle cells, and reversing these modifications can lessen the stiffness and improve the beating strength of these cells isolated from transplant patients with heart failure, found researchers from the Perelman School of Medicine at the University of Pennsylvania.

12 Jun 2018

Synthetic gene reveals potential therapeutic target for rare, inherited disease

DNA Repair is essential for a healthy organism. In every day of our lives, tens of thousands of damages occur in the genetic material of our cells. Hence, it is not surprising that a broad variety of repair mechanisms developed in the course of evolution that enables cells to quickly react and patch up the affected DNA strands.

11 Jun 2018

Researchers identify enzyme that controls cell’s collagen secretion

Researchers at Tokyo Institute of Technology have identified an enzyme that controls how much our cells secrete collagen.

11 Jun 2018

Researchers reverse tau-induced memory deficits in animal models

Reversing memory deficits and impairments in spatial learning is a major goal in the field of dementia research. A lack of knowledge about cellular pathways critical to the development of dementia, however, has stood in the way of significant clinical advance.

8 Jun 2018

Alnylam announces new positive results from Phase 1/2 study of lumasiran in patients with PH1

Alnylam Pharmaceuticals, Inc., the leading RNAi therapeutics company, announced today new positive results from its Phase 1/2 study with lumasiran, an investigational RNAi therapeutic targeting glycolate oxidase for the treatment of Primary Hyperoxaluria Type 1.

8 Jun 2018

Some tumors use two levels of protection against immune system, shows study

In research published today, Babraham Institute researchers have shown that some tumors use not one but two levels of protection against the immune system.

8 Jun 2018

Researchers discover new therapy combination that may help treat ovarian cancer

Researchers at The University of Kansas Cancer Center have discovered a therapy combination that may be helpful in the treatment of certain types of ovarian cancer.

8 Jun 2018

UCLA researchers have blueprint of telomerase that plays major role in cancer, aging

Cancer, aging-related diseases and other illnesses are closely tied to an important enzyme called "telomerase." UCLA researchers report in the journal Cell the deepest scientific understanding yet of this once-mysterious enzyme, whose catalytic core -- where most of its activity occurs -- can now be seen in near atomic resolution.

7 Jun 2018