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Chronic pain common in affective disorders

Patients with major depressive disorder or bipolar disorder frequently report chronic pain at multiple sites, research shows.

30 Jan 2015

Synthetic compound shows antibiotic action against MRSA

Microbiologists and chemists at the University of South Florida have developed and patented a synthetic compound that has shown antibiotic action against methicillin resistant Staphylococcus aureus, also known as MRSA, which can cause many serious infections and deaths.

30 Jan 2015

Online social connectedness promotes weight loss, shows study

If you want to lose pounds using an online weight management program, don't be a wallflower. A new Northwestern University study shows that online dieters with high social embeddedness -- who logged in regularly, recorded their weigh-ins and 'friended' other members -- lost more than 8 percent of their body weight in six months.

29 Jan 2015

EGFR–TKI response worse in NSCLC patients with rare EGFR mutations

In patients with non-small-cell lung cancer, rare epidermal growth factor receptor mutations are associated with a poorer response to EGFR–tyrosine kinase inhibitors compared with frequently occurring ones, according to a study published in Lung Cancer.

28 Jan 2015

Researchers advance generalized concept for future studies of mental resilience

Researchers at the Research Center Translational Neurosciences of Johannes Gutenberg University Mainz in Germany have advanced a generalized concept as the basis for future studies of mental resilience. Their new approach is based on a mechanistic theory which takes as its starting point the appraisals made by the brain in response to exposure to stressful or threatening situations.

28 Jan 2015

Study provides new route for treating patients with difficult-to-treat Parkinson's symptoms

Parkinson's disease patients treated with low-frequency deep brain stimulation show significant improvements in swallowing dysfunction and freezing of gait over typical high-frequency treatment.

28 Jan 2015

Bronchial thermoplasty for severe asthma: an interview with Dr. Rob Niven

Internationally, severe asthma is defined as anybody who is on maximum therapy, which has no measurable side effects, but still have symptoms of persistent asthma. In the UK, that effectively means people who require oral steroids for their asthma two or more times a year.

27 Jan 2015

Alcohol drinking pattern influences risk of cirrhosis

Approximately 170,000 people die from alcoholic cirrhosis of the liver in Europe every year. Although alcohol is the most important risk factor, less is known about the significance of different patterns of drinking. Currently scientists believe that cirrhosis is a function of the volume of alcohol consumed irrespective of patterns of drinking. Investigators have now established that alcohol drinking pattern has a significant influence on the risk of cirrhosis and that daily drinking increases that risk compared with drinking less frequently.

27 Jan 2015

International scientists take new path in epilepsy research

An international team of scientists together with the University of Bonn Hospital have taken a new path in the research into causes of epilepsy: The researchers determined the networks of the active genes and, like a dragnet, looked for the "main perpetrators" using a computer model.

24 Jan 2015

Cypher Genomics, Sequenom sign development agreement for noninvasive prenatal tests

Cypher Genomics, Inc., the leading genome informatics company, and Sequenom, Inc., the leading molecular diagnostics company, today announced a development agreement for next generation noninvasive prenatal tests (NIPT).

22 Jan 2015

Study: Mutated ATRX gene may serve as much-needed biomarker for rare neuroendocrine tumors

A somatic mutation in the ATRX gene has recently been shown as a potential molecular marker for aggressive brain tumors, such as gliomas, neuroblastomas and pancreatic neuroendocrine tumors. Now, for the first time, researchers at Penn's Abramson Cancer Center have found that the same mutated gene may serve as a much-needed biomarker for the pheochromocytomas and paragangliomas (PCC/PGL) that become malignant.

21 Jan 2015

Exposure to alcohol TV ads associated with underage drinking

Seeing and liking alcohol advertising on television among underage youths was associated with the onset of drinking, binge drinking and hazardous drinking, according to a study by researchers at the Norris Cotton Cancer Center and Children's Hospital at Dartmouth-Hitchcock published online by JAMA Pediatrics.

21 Jan 2015

MET amplified in NSCLC irrespective of type, genetic background

A third of non-small-cell lung cancers show low- to high-level amplification of the MET gene, according to a German study, with no significant difference in frequency across different types of cancer and genetic backgrounds.

20 Jan 2015

Effective vaccine booster schedules needed to fight against whooping cough resurgence

A key to victory in battle, according to Chinese general and military strategist Sun Tzu, is to know your enemy. In the current fight against whooping cough resurgence, perhaps the biggest obstacle is an incomplete understanding of its underlying causes, according to a University of Michigan population ecologist.

20 Jan 2015

Researchers turn clinical experience in multiple myeloma treatment into instructive review for physicians

Multiple myeloma is a malignant disease characterised by proliferation of clonal plasma cells in the bone marrow and typically accompanied by the secretion of monoclonal immunoglobulins that are detectable in the serum or urine. Increased understanding of the microenvironmental interactions between malignant plasma cells and the bone marrow niche, and their role in disease progression and acquisition of therapy resistance, has helped the development of novel therapeutic drugs for use in combination with cytostatic therapy.

20 Jan 2015

Scientists identify first genetic marker linked to severe neurological toxicity

Paclitaxel is a chemotherapeutic drug that has been shown to be highly effective when treating solid tumours, such as breast, ovarian and lung tumours. However, its use frequently causes peripheral neuropathies, neurological problems that affect the vast majority of patients.

15 Jan 2015

Researchers develop novel method to predict risk of liver cancer recurrence after transplantation

UCLA transplantation researchers have developed a novel method that more accurately calculates the risk of disease recurrence in liver cancer patients who have undergone a liver transplant, providing a new tool to help physicians make treatment and surveillance decisions.

14 Jan 2015

eAgile releases new UHF EPC compliant MicroWing inlay

eAgile Inc., a global leader in radio frequency identification (RFID) technologies, announced today the release of their new UHF EPC compliant MicroWing inlay. The MicroWing is the size of a paper clip which makes it the smallest RFID inlay available on the market to achieve a greater than 2 meter read range.

13 Jan 2015

EGFR mutations, ALK translocations not mutually exclusive in NSCLC

Researchers from the Republic of Korea have found that epidermal growth factor receptor mutations and anaplastic lymphoma kinase translocations can occur concomitantly in a proportion of patients with non-small-cell lung cancer.

12 Jan 2015

Survey shows radiation oncologists desire for more formal guidance to improve peer review process

Peer review is a common practice in medicine to support the complementary, multidisciplinary team approach in healthcare. A 2013 survey of radiation oncologists indicates that they would like more formal recommendations and guidance in order to improve the peer review process, according to a study published in the January-February 2015 issue of Practical Radiation Oncology, the clinical practice journal of the American Society for Radiation Oncology.

8 Jan 2015

Frequency News and Research

Chronic pain common in affective disorders

Synthetic compound shows antibiotic action against MRSA

Online social connectedness promotes weight loss, shows study

EGFR–TKI response worse in NSCLC patients with rare EGFR mutations

Researchers advance generalized concept for future studies of mental resilience

Study provides new route for treating patients with difficult-to-treat Parkinson's symptoms

Bronchial thermoplasty for severe asthma: an interview with Dr. Rob Niven

Alcohol drinking pattern influences risk of cirrhosis

International scientists take new path in epilepsy research

Cypher Genomics, Sequenom sign development agreement for noninvasive prenatal tests

Study: Mutated ATRX gene may serve as much-needed biomarker for rare neuroendocrine tumors

Exposure to alcohol TV ads associated with underage drinking

MET amplified in NSCLC irrespective of type, genetic background

Effective vaccine booster schedules needed to fight against whooping cough resurgence

Researchers turn clinical experience in multiple myeloma treatment into instructive review for physicians

Scientists identify first genetic marker linked to severe neurological toxicity

Researchers develop novel method to predict risk of liver cancer recurrence after transplantation

eAgile releases new UHF EPC compliant MicroWing inlay

EGFR mutations, ALK translocations not mutually exclusive in NSCLC

Survey shows radiation oncologists desire for more formal guidance to improve peer review process

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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