Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

Research explores the advancements, challenges, and economic implications of gene therapy for various diseases, including inherited blood disorders, malignancies treated with CAR-T cells, and diseases targeted by in vivo AAV vectors. The review highlights the transformative potential of gene therapies while acknowledging the complexities in manufacturing, safety, efficacy, and long-term durability.

12 Nov 2023

DZNE neuroscientist receives grant to study link between neurodegenerative diseases and mental health

Neurodegenerative diseases like Alzheimer's and Parkinson's can be associated to depression and anxiety. Dr. Sabine Krabbe, a neuroscientist at DZNE's Bonn site, is receiving 1.2 million US dollars from the Chan Zuckerberg Initiative to understand the mechanisms involved in the onset of these syndromes.

10 Nov 2023

Obinutuzumab shows promise in preserving kidney function, preventing flares in lupus nephritis patients

In a post hoc analysis of the phase 2 NOBILITY trial, researchers found that treatment with obinutuzumab - an antibody that targets a protein expressed on certain immune cells - was superior to placebo for preserving kidney function and preventing flares in patients with lupus nephritis, a kidney condition associated with the autoimmune disease lupus.

10 Nov 2023

Data, Design, and Discovery: Andrew Buchanan's Impact on Biologics Innovation

Andrew Buchanan on the Future of Biologics and AI

10 Nov 2023

Revolution by Evolution: Protein Science and its Impact on Drug Discovery

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Mark Abbott, the Managing Director of Peak Proteins, about protein science and its significance in drug discovery.

10 Nov 2023

Brazzein and monellin: Safe alternatives to sugar, new research confirms

Toxicity assessments of monellin and brazzein.

10 Nov 2023

Research redefines rheumatoid arthritis: Over 314,000 cells analyzed for precise treatment strategies

A new paper recently published in Nature, reported the examination of synovial tissue from the joints of nearly 80 people with RA, in combination with RNA sequencing and surface protein analyses.

10 Nov 2023

Debate intensifies over vegan diets for children, pediatric associations weigh in

Evidence on vegan (VN) diets for pediatric and adolescent individuals.

10 Nov 2023

Ongoing study investigates if ultra-processed foods influence brain chemistry and obesity risk in young adults

Researchers are exploring how diets high in ultra-processed foods influence reward processing in the brain and potentially lead to increased food intake and obesity in young adults. This trial aims to clarify the effects of these foods on brain chemistry and decision-making during a critical developmental stage.

9 Nov 2023

SDF-4 protein shows promise for early detection of gastric cancer

A research team led by the Nagoya University Graduate School of Medicine has discovered that the stromal cell-derived factor 4 (SDF-4) protein is a reliable cancer marker.

9 Nov 2023

UCLA researchers discover key step in cholesterol processing

UCLA researchers have described a previously unknown step in the complex process by which dietary cholesterol is processed in the intestines before being released into the bloodstream – potentially revealing a new pathway to target in cholesterol treatment.

9 Nov 2023

Researchers reveal mechanism by which MAF protein increases metastasis risk in breast cancer patients

Breast cancer is the most common form of cancer among women, with more than 2 million new cases diagnosed each year. In cases where the tumour remains localised in the breast, survival rates are remarkably high, at around 90%.

9 Nov 2023

Preclinical discovery could point the way toward better treatments for type 2 diabetes

A drug currently in clinical trials as a cancer therapy can also stimulate pancreatic beta cells to secrete insulin, revealing a previously unknown mechanism for insulin regulation in type 2 diabetes, according to a new study by Weill Cornell Medicine investigators.

9 Nov 2023

Study reveals early role of SYNGAP1 gene in brain development

The gene SYNGAP1, the variants of which are top risk factors for Autism Spectrum Disorder (ASD), has previously unappreciated effects on the developing brain, according to a new study published in Nature Neuroscience.

9 Nov 2023

Researchers identify a novel bacterial protein that can keep human cells healthy

Researchers at the University of São Paulo (USP) in Brazil, partnering with colleagues in Australia, have identified a novel bacterial protein that can keep human cells healthy even when the cells have a heavy bacterial burden.

9 Nov 2023

COVID Moonshot Consortium makes major breakthrough in antiviral drug discovery

The work of the COVID Moonshot Consortium is being published in the prestigious journal Science on 10 November, revealing their discovery of a potent SARS-CoV-2 antiviral lead compound.

9 Nov 2023

Bio Farma's Bio-TCV typhoid conjugate vaccine licensed in Indonesia following marketing approval

The International Vaccine Institute (IVI), an international organization with a mission to discover, develop, and deliver safe, effective, and affordable vaccines for global health, and Bio Farma, a biotechnology company based in West Java, Indonesia, announced today that Bio Farma's Bio-TCV typhoid conjugate vaccine (TCV) was licensed in Indonesia following marketing approval from Badan Pengawas Obat dan Makanan (BPOM), the national regulatory authority.

9 Nov 2023

Scientists discover kidney-friendly antifungal that evades resistance

In this investigation, researchers produced powerful antifungals of the polyene class without nephrotoxicity.

9 Nov 2023

Charting the future of IBD treatment: From immune modulators to microRNA therapies

In a recent study published in the journal eGastroenterology, researchers delved into the latest therapeutic strategies for managing inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The paper discusses emerging treatments ranging from immune-modulating drugs and biologics to novel approaches like microRNA upregulators and stem cell therapies, highlighting the need for precision medicine in IBD care.

8 Nov 2023

Cannabis use alters DNA methylation, with implications beyond smoking effects

A large-scale meta-analysis in Molecular Psychiatry reveals that lifetime cannabis use is associated with DNA methylation changes in peripheral blood, which could have implications for understanding the long-term health effects of cannabis consumption.

8 Nov 2023

Protein News and Research

Further Reading

Gene therapy's double-edged sword: Breakthrough treatments face manufacturing and efficacy

DZNE neuroscientist receives grant to study link between neurodegenerative diseases and mental health

Obinutuzumab shows promise in preserving kidney function, preventing flares in lupus nephritis patients

Data, Design, and Discovery: Andrew Buchanan's Impact on Biologics Innovation

Revolution by Evolution: Protein Science and its Impact on Drug Discovery

Brazzein and monellin: Safe alternatives to sugar, new research confirms

Research redefines rheumatoid arthritis: Over 314,000 cells analyzed for precise treatment strategies

Debate intensifies over vegan diets for children, pediatric associations weigh in

Ongoing study investigates if ultra-processed foods influence brain chemistry and obesity risk in young adults

SDF-4 protein shows promise for early detection of gastric cancer

UCLA researchers discover key step in cholesterol processing

Researchers reveal mechanism by which MAF protein increases metastasis risk in breast cancer patients

Preclinical discovery could point the way toward better treatments for type 2 diabetes

Study reveals early role of SYNGAP1 gene in brain development

Researchers identify a novel bacterial protein that can keep human cells healthy

COVID Moonshot Consortium makes major breakthrough in antiviral drug discovery

Bio Farma's Bio-TCV typhoid conjugate vaccine licensed in Indonesia following marketing approval

Scientists discover kidney-friendly antifungal that evades resistance

Charting the future of IBD treatment: From immune modulators to microRNA therapies

Cannabis use alters DNA methylation, with implications beyond smoking effects

Editorial Focus eBook - Proteomics eBook

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Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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