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Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Researchers describe molecular signalling regulated by mTOR among memory and exhausted cytotoxic CD8+ T lymphocytes.

18 Aug 2023

Lorazepam linked to shorter progression-free survival in pancreatic cancer patients

Patients with pancreatic cancer who took the benzodiazepine lorazepam (Ativan), commonly prescribed to treat anxiety during cancer treatment, had a shorter progression-free survival than patients who did not, according to results published in Clinical Cancer Research, a journal of the American Association for Cancer Research (AACR).

17 Aug 2023

Immunotherapy combination extends progression-free survival in patients with melanoma

A research team co-led by UCLA investigators has shown that an immunotherapy drug combination can be an effective second-line therapy for patients with an aggressive and deadly type of melanoma that is resistant to the widely used immunotherapy drugs known as PD-1 inhibitors.

17 Aug 2023

New insights into the role of liver progenitor cells in liver cancer initiation

Primary liver cancers ranked as the sixth most commonly diagnosed cancers and the third leading cause of cancer-related death in 2020. Among all primary liver cancers, HCC is the most common cancer, accounting for more than 80% of cases with a 5-year survival rate of less than 10% in Western countries.

17 Aug 2023

Researchers receive DoD grant to target chemotherapy resistance in pancreatic cancer

Researchers with Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have been awarded a grant from the U.S. Department of Defense (DoD)'s Congressionally Directed Medical Research Program to target chemotherapy resistance in pancreatic cancer.

17 Aug 2023

New study offers preliminary estimates of mortality risk by stage in Alzheimer's disease

Researchers examine the expected survival of people at each stage of Alzheimer's disease.

17 Aug 2023

Does depression in caregivers affect the prognosis of Parkinson’s disease patients?

Researchers assessed the relationship between care providers with depressive symptoms and the quality of life, hospital admissions, and emergency department consultations of Parkinson’s disease patients.

17 Aug 2023

Potential of COVID-19 convalescent plasma for future monoclonal antibodies against severe SARS-CoV-2 inflammation

Researchers report that convalescent plasma treatment is most effective in treating hospitalized COVID-19 patients.

17 Aug 2023

Brief nurse-delivered sleep restriction therapy in primary care is clinically effective for insomnia disorder, safe, and likely to be cost-effective

Researchers compare the cost-effectiveness and clinical impact of nurse-delivered sleep restriction therapy with sleep hygiene for insomnia treatment.

17 Aug 2023

Prior vaccinations may help protect against Alzheimer's disease

Prior vaccination against tetanus and diphtheria, with or without pertussis (Tdap/Td); herpes zoster (HZ), better known as shingles; and pneumococcus are all associated with a reduced risk for developing Alzheimer's disease, according to new research from UTHealth Houston.

16 Aug 2023

Study sheds light on how cold temperatures affect appetite

Neuroscientists at Scripps Research have identified brain circuits that make mammals want to eat more when they are exposed to cold temperatures.

16 Aug 2023

Some early-stage, low-risk breast cancer patients may not need radiotherapy after surgery

Some women with early-stage, low-risk breast cancer may not need radiotherapy after breast conserving surgery according to new research led by McMaster University, BC Cancer, Hamilton Heath Sciences, and the University of British Columbia.

16 Aug 2023

Study: 93 million U.S. adults may benefit from semaglutide medication

Researchers from the University of California, Irvine have just published a study that projects 93 million U.S. adults that are overweight and obese may be suitable for the 2.4 mg dosage of semaglutide, a weight loss medication known under the brand name Wegovy.

16 Aug 2023

SIO and ASCO recommend mindfulness-based interventions for anxiety, depression in cancer patients

The Society for Integrative Oncology (SIO) and the American Society of Clinical Oncology (ASCO) formally recommend mindfulness-based interventions (MBIs) and other integrative therapies to manage anxiety and depression symptoms in adults living with cancer.

16 Aug 2023

What gestational age at delivery is associated with the best perinatal outcomes in term singleton pregnancies conceived with infertility treatment?

Researchers investigated the age of gestation associated with optimal perinatal outcomes among in-term single-infant pregnancies conceived using infertility therapies.

16 Aug 2023

Therapy News and Research

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Lorazepam linked to shorter progression-free survival in pancreatic cancer patients

Immunotherapy combination extends progression-free survival in patients with melanoma

New insights into the role of liver progenitor cells in liver cancer initiation

Researchers receive DoD grant to target chemotherapy resistance in pancreatic cancer

New study offers preliminary estimates of mortality risk by stage in Alzheimer's disease

Does depression in caregivers affect the prognosis of Parkinson’s disease patients?

Potential of COVID-19 convalescent plasma for future monoclonal antibodies against severe SARS-CoV-2 inflammation

Brief nurse-delivered sleep restriction therapy in primary care is clinically effective for insomnia disorder, safe, and likely to be cost-effective

Prior vaccinations may help protect against Alzheimer's disease

Study sheds light on how cold temperatures affect appetite

Some early-stage, low-risk breast cancer patients may not need radiotherapy after surgery

Study: 93 million U.S. adults may benefit from semaglutide medication

SIO and ASCO recommend mindfulness-based interventions for anxiety, depression in cancer patients

What gestational age at delivery is associated with the best perinatal outcomes in term singleton pregnancies conceived with infertility treatment?

Study explores the challenges of the clinical diagnoses of acute exacerbation of chronic obstructive pulmonary disease

Androgen deprivation therapy increases the risk of depression, dementia, Alzheimer’s disease, and Parkinson’s disease

Copy number profiling provides insight as to why prostate cancer may become lethal

Proton radiotherapy used for the first time in Switzerland to treat esophageal tumor

Early lung cancer detection with a machine learning model based on imaging, clinical, and DNA methylation biomarkers

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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