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NIAID study identifies critical T-cell function missing in prior HIV vaccine candidates

An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study from researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and colleagues.

14 Dec 2023

Researchers develop a framework to identify potentially hidden genetic contributors to disease

Genome-wide association studies (GWAS) on patient blood samples are useful for identifying the genetic basis of blood cell traits and their links to common diseases.

14 Dec 2023

Rapid identification of disease-causing bacteria using Raman spectroscopy

Study in BioRisk explores the use of Raman spectroscopy for rapid identification of Pseudomonas aeruginosa, a bacteria causing serious human diseases, demonstrating its potential as a quick and efficient diagnostic tool.

14 Dec 2023

Researchers identify the culprit responsible for harmful inflammation in certain muscular disorders

Inflammation is an important part of the body's defenses, eliminating threats and repairing damage. When the immune system is overactivated, though, it can turn from friend to foe.

14 Dec 2023

New advance in the development of a test for early diagnosis of cancer

Blood cells reveal tumors in the body. Researchers at the Paul Scherrer Institute achieve an advance with the development of a test for early diagnosis of cancer.

14 Dec 2023

D-mannose could improve age-associated urinary tract dysfunction and help reduce UTIs

Aging poses a number of challenges to the body's well-being, one of the most important being an increased susceptibility to multiple diseases, including urinary tract infections (UTIs).

14 Dec 2023

Researchers unveil new way to sensitize resistant tumors to treatment

Resistance to therapies is one of the obstacles to overcome in cancer treatments. Understanding the mechanisms of this resistance is essential to design strategies that favor tumor cell death.

14 Dec 2023

Spinal cord stimulation restores sensation and eases phantom pain in amputees

Spinal cord stimulation can elicit sensation in the missing foot and alleviate phantom limb pain in people with lower limb amputations, University of Pittsburgh School of Medicine rehabilitation scientists report today.

14 Dec 2023

Study suggests possible targets for the development of a vaccine against multiple sclerosis

Multiple sclerosis (MS) is a chronic inflammatory autoimmune disease in which the Epstein-Barr virus (EBV) is thought to play a role that has not yet been fully clarified.

14 Dec 2023

Researchers develop humanized mouse model for macrophage-targeted cancer immunotherapy

Mice with human immune cells are a new way of testing anti-cancer drugs targeting the immune system in pre-clinical studies.

14 Dec 2023

IFNγ identified as crucial for reducing pulmonary viral loads in COVID-19, new research shows

The role of type-2 interferon (IFNγ) in antiviral immunity.

14 Dec 2023

Research shows correlation between neonatal proteins and adult health

Research led by Professor John McGrath from the University of Queensland found that the concentration of the C4 protein, an important part of the immune system, was not associated with risk of mental disorders.

13 Dec 2023

High insulin response can be your health ally, study says

Researchers at Sinai Health have unearthed vital information about the relationship between insulin levels after eating and long-term heart and metabolic health.

13 Dec 2023

Genetic link to premature ovarian insufficiency explained: A mitochondrial perspective

Infertility affects around 48 million couples worldwide and can have various causes. In mammals, including humans, eggs are produced in the ovary.

13 Dec 2023

Smaller mpox vaccine doses and intradermal delivery elicit detectable immune response, study shows

Delivering the two-dose mpox vaccine, called JYNNEOS, in smaller than the usual FDA-approved doses, and by injection between layers of the skin rather than by the standard route under the skin, produced a detectable immune response, a new study shows.

13 Dec 2023

Simple trick supercharges T cells to fight stubborn solid tumors

Wistar researchers successfully tested a simple intervention that could unlock greater anti-tumor power in therapies that use T cells - an approach known as "cell-based therapy," which uses specially designed T cells to fight cancer.

13 Dec 2023

Targeting cholesterol metabolism for the treatment of serrated colorectal neoplasms

Hard-to-detect colorectal pre-cancerous lesions known as serrated polyps, and the aggressive tumors that develop from them, depend heavily on the ramped-up production of cholesterol, according to a preclinical study from researchers at Weill Cornell Medicine.

13 Dec 2023

$153,000 grant fuels research on new approaches to inhibit STAT3 and develop novel cancer treatments

With an estimated 1.9 million new cases and more than 600,000 deaths each year, cancer remains the second most common cause of death in the U.S., trailing only heart disease. And while there are more than 200 types of cancer, the abnormal synthesis of a protein known as STAT3 is unique to the majority of tumors.

13 Dec 2023

Developing a virtual twin for personalized cancer treatment with CAR-T cell therapy

In recent years, cancer immunotherapies have established themselves as a further pillar of medical oncology alongside traditional treatment options (surgery, radiotherapy and chemotherapy).

13 Dec 2023

Understanding why cutting-edge cell therapies cause an increased risk of heart rhythm disorders

A type of cell that plays a crucial role in tissue repair after a heart attack may also inadvertently be why cutting-edge cell therapies cause an increased risk of rhythm disorders, according to a new study from the Universities of Surrey and Oxford.

13 Dec 2023

B Cell News and Research

NIAID study identifies critical T-cell function missing in prior HIV vaccine candidates

Researchers develop a framework to identify potentially hidden genetic contributors to disease

Rapid identification of disease-causing bacteria using Raman spectroscopy

Researchers identify the culprit responsible for harmful inflammation in certain muscular disorders

New advance in the development of a test for early diagnosis of cancer

D-mannose could improve age-associated urinary tract dysfunction and help reduce UTIs

Researchers unveil new way to sensitize resistant tumors to treatment

Spinal cord stimulation restores sensation and eases phantom pain in amputees

Study suggests possible targets for the development of a vaccine against multiple sclerosis

Researchers develop humanized mouse model for macrophage-targeted cancer immunotherapy

IFNγ identified as crucial for reducing pulmonary viral loads in COVID-19, new research shows

Research shows correlation between neonatal proteins and adult health

High insulin response can be your health ally, study says

Genetic link to premature ovarian insufficiency explained: A mitochondrial perspective

Smaller mpox vaccine doses and intradermal delivery elicit detectable immune response, study shows

Simple trick supercharges T cells to fight stubborn solid tumors

Targeting cholesterol metabolism for the treatment of serrated colorectal neoplasms

$153,000 grant fuels research on new approaches to inhibit STAT3 and develop novel cancer treatments

Developing a virtual twin for personalized cancer treatment with CAR-T cell therapy

Understanding why cutting-edge cell therapies cause an increased risk of heart rhythm disorders

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