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Gene variants associated with acute kidney injury in Black veterans hospitalized with COVID-19

Gene variants increased the risk of acute kidney injury and death in veterans of African ancestry who were hospitalized with COVID-19, according to a new study published in JAMA Internal Medicine.

10 Feb 2022

Epigenetic effects of pollutants may persist long enough to influence the evolutionary process

A new study led by University of Liverpool researchers has shown that the effects of pollutants can be transmitted over many generations in water fleas and may persist long enough to influence the evolutionary process.

10 Feb 2022

New rapid, cheaper test could help advance personalized cancer treatment

Using a routine blood sample, investigators have developed an extremely sensitive assay to detect and quantify DNA fragments containing rare genetic mutations in a patient's cancer cells.

10 Feb 2022

Researchers identify and characterize a previously unrecognized key player in cancer evolution

Researchers led by bioengineers at the University of California San Diego have identified and characterized a previously unrecognized key player in cancer evolution: clusters of mutations occurring at certain regions of the genome.

9 Feb 2022

Study explores wastewater surveillance of US military installations to mitigate the spread of SARS-CoV-2

Researchers investigated the application of wastewater surveillance of seagoing military vessels and U.S. coast guard installations to mitigate the spread of SARS-CoV-2.

9 Feb 2022

Prevalence of genetic susceptibility to cardiac arrhythmia may be underestimated, study says

By sequencing known genes associated with cardiac arrhythmia risk in more than 20,000 people without an indication for genetic testing, scientists were able to identify pathogenic and likely pathogenic variants in nearly one percent of individuals, according to a study published in Circulation.

9 Feb 2022

Single-cell sequencing provides detailed insight into early SARS-CoV-2 infection in the lungs

What is going on at the single-cell level in the first days of SARS-CoV-2 infection in the lungs?

9 Feb 2022

Research reveals why Black women experience higher breast cancer mortality

New research from Sanford Burnham Prebys has revealed significant molecular differences between the breast cells of white and Black women that help explain why Black women experience higher breast cancer mortality.

9 Feb 2022

Research findings provide a potential roadmap for metastatic tumor formation

Using data from over 100,000 malignant and non-malignant cells from 15 human brain metastases, UCSF researchers have revealed two functional archetypes of metastatic cells across 7 different types of brain tumors, each containing both immune and non-immune cell types.

9 Feb 2022

Innate immune specificity is driven by the nervous system, study suggests

Research led by Washington State University scientists supports a novel theory that the innate immune system people are born with can respond differently to specific pathogens.

9 Feb 2022

Scientists identify a new protein that prevents cancer cell migration

When tumors spread, cancer cells migrate to other parts of the body through the blood or lymphatic vessels. Scientists at the Institute of Science and Technology Austria have now found a new protein that prevents cancer cells from doing so by making them stick more tightly to their surroundings.

9 Feb 2022

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

In a new study, researchers revealed that the nucleotide-binding oligomerization domain-like receptors or NOD-like receptors family pyrin domain containing 3 (NLRP3) inflammasome is activated by the exosomes from plasma in COVID-19.

9 Feb 2022

Researchers identify a bivalent histone-mark switch essential for angiogenesis

Defying conventional epigenomic wisdom, the non-conventional polycomb (PRC)1 variant paradoxically overwhelms the conventional PRC-mediated gene silencing in activated endothelial cells.

8 Feb 2022

Defective mitochondrial DNA could be modified using gene-editing techniques

Defective mitochondria – the 'batteries' that power the cells of our bodies – could in future be repaired using gene-editing techniques.

8 Feb 2022

Study shows how gut bacteria could undermine immunity in pancreatic cancer

Researchers at the University of Toronto and University Health Network have shown how probiotic bacteria in the gut could undermine immunity in pancreatic cancer, pointing toward more personalized cancer treatments.

8 Feb 2022

Gut microbiome modulation induces behavioral, cognitive changes in Alzheimer's disease model

New research in mice for the first time draws a definitive causal connection between changes in the gut microbiome to behavioral and cognitive changes in an animal model of Alzheimer's disease.

8 Feb 2022

Compounds used to fight fungal diseases in plants may be driving antimicrobial resistance

New research from the University of Georgia has shown, for the first time, that compounds used to fight fungal diseases in plants are causing resistance to antifungal medications used to treat people.

8 Feb 2022

NIH grant renewal will enable Nebraska scientist to advance research on virtual immune system

The renewal of a National Institutes of Health grant will enable a University of Nebraska-Lincoln researcher to continue developing a tool that illuminates the complex, multi-scale interplay of the immune system's many components.

8 Feb 2022

Antibody drug improves survival rates in canine prostate cancer model

Dogs are proving to be a far better scientific model for study of prostate cancer than mice, the typical animal used in the lab for this type of research.

8 Feb 2022

Regulatory sequences in the genomes of mammals help explain how cancer invades normal tissues

Researchers from UConn Heath and Yale University have made new advances connecting the evolution of pregnancy and cancer metastasis.

8 Feb 2022

Genes News and Research

Gene variants associated with acute kidney injury in Black veterans hospitalized with COVID-19

Epigenetic effects of pollutants may persist long enough to influence the evolutionary process

New rapid, cheaper test could help advance personalized cancer treatment

Researchers identify and characterize a previously unrecognized key player in cancer evolution

Study explores wastewater surveillance of US military installations to mitigate the spread of SARS-CoV-2

Prevalence of genetic susceptibility to cardiac arrhythmia may be underestimated, study says

Single-cell sequencing provides detailed insight into early SARS-CoV-2 infection in the lungs

Research reveals why Black women experience higher breast cancer mortality

Research findings provide a potential roadmap for metastatic tumor formation

Innate immune specificity is driven by the nervous system, study suggests

Scientists identify a new protein that prevents cancer cell migration

Study explores inflammation of endothelial cells by exosomes from COVID-19 patients

Researchers identify a bivalent histone-mark switch essential for angiogenesis

Defective mitochondrial DNA could be modified using gene-editing techniques

Study shows how gut bacteria could undermine immunity in pancreatic cancer

Gut microbiome modulation induces behavioral, cognitive changes in Alzheimer's disease model

Compounds used to fight fungal diseases in plants may be driving antimicrobial resistance

NIH grant renewal will enable Nebraska scientist to advance research on virtual immune system

Antibody drug improves survival rates in canine prostate cancer model

Regulatory sequences in the genomes of mammals help explain how cancer invades normal tissues

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