Therapy News and Research

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Blood test for pan-cancer biomarker could revolutionize early cancer detection

Diagnostic tools for timely, accurate and inexpensive early cancer detection that can assess risk or monitor response to treatment could help patients get the care they need faster and improve existing care strategies.

5 Oct 2023

Researchers discover a vulnerability in immunotherapy-resistant triple-negative breast cancer

Researchers at Vanderbilt-Ingram Cancer Center have discovered a druggable target on natural killer cells that could potentially trigger a therapeutic response in patients with immunotherapy-resistant, triple-negative breast cancer.

5 Oct 2023

CRISPR gene editing study provides insights into how autism gene affects brain development

Researchers have used CRISPR gene editing, stem cells and human neurons to study the impact of a gene that is commonly mutated in autism.

5 Oct 2023

Automated insulin delivery could be a game-changer for pregnant women with type 1 diabetes

Automated insulin delivery should be rolled out to pregnant women with type 1 diabetes - according to researchers at the University of East Anglia.

5 Oct 2023

Psychedelic therapy shows promise for treating veterans with PTSD and brain injury

One treatment each of two psychedelic drugs lowered depression and anxiety and improved cognitive functioning in a sample of U.S. special operations forces veterans who sought care at a clinic in Mexico, according to a new analysis of the participants' charts.

5 Oct 2023

Unlocking the future of cancer care: Overcoming challenges in personalized neoantigen vaccine development

Challenges associated with the development and design of neoantigen cancer vaccines.

5 Oct 2023

Optimized protocol to prevent disease transmission through maternal mitochondrial DNA carryover

Researchers discuss a novel technique to minimize the risk of mtDNA carryover, thereby preventing genetic risk and clinical mitochondrial disease.

5 Oct 2023

The metabolic effects of endocrine therapy on diabetes mellitus in breast cancer survivors

Researchers discuss the history of endocrine therapies, highlights their adverse metabolic effects, and emphasizes the need for better biomarkers of diabetes.

5 Oct 2023

Can falsified or substandard antimicrobials increase antimicrobial resistance?

The association between substandard or falsified (SF) antibiotics and antimicrobial resistance (AMR).

5 Oct 2023

Remote ischemic conditioning for acute stroke

The effect of remote ischemic conditioning (RIC) on functional outcomes in patients with acute stroke.

5 Oct 2023

Esketamine nasal spray superior in achieving remission in patients with treatment-resistant depression

Both severe depression and treatment-resistant depression are common. Up to one third of patients do not respond to conventional therapy with antidepressants such as selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs).

5 Oct 2023

New zebrafish xenograft platform could help screen for glioblastoma treatments

Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new study by the Gerhardt and De Smet labs published in EMBO Molecular Medicine.

4 Oct 2023

USC receives $2 million grant to advance cell and gene therapy research

The Keck School of Medicine of USC has received $2 million from the California Institute of Regenerative Medicine (CIRM) to further augment its newly launched cGMP Laboratory, a state-of-the-art facility designed to advance early-stage research into clinically viable cell and gene therapies.

4 Oct 2023

Esketamine outperforms one of the standard drugs for treatment-resistant major depression

A major clinical trial shows that the drug, esketamine, one of the two main forms of ketamine, outperforms one of the standard treatments for treatment-resistant major depression.

4 Oct 2023

Study confirms accuracy of Vienna Prediction Model for venous thromboembolism

A prediction model can be used to identify people affected by venous thromboembolism who have only a low risk of recurrence and may not require long-term blood thinning.

4 Oct 2023

New workflow could significantly reduce wait time for urgent palliative radiation therapy

Using previously taken diagnostic computed tomography (CT) scans in place of CT simulation scans to plan simple palliative radiation treatments can substantially reduce the time some people spend waiting for urgent treatment, improving the patient experience, a new study suggests.

4 Oct 2023

Experts to discuss if lasting remission from diabetes is feasible in real-world setting

At this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Hamburg, Germany (2-6 Oct) experts will discuss if lasting remission from diabetes is feasible in the real-world setting.

4 Oct 2023

Nearly half of the people with HIV, diabetes or hypertension in rural South Africa have unmet health needs

The burden of non-communicable diseases like hypertension and diabetes is increasing globally, especially in low-income and middle-income countries where they occur alongside epidemics of communicable diseases like HIV.

4 Oct 2023

Measuring ctDNA may lead to alternative treatment options for BRAF wild-type melanoma

Circulating tumor DNA (ctDNA) is emerging as a blood-based biomarker for many solid tumor types, including melanoma.

4 Oct 2023

Early metformin therapy falls short in curbing gestational diabetes woes

In a significant randomized clinical trial, early metformin therapy was tested for its potential to lessen insulin dependence and enhance glycemic control in gestational diabetes-afflicted pregnant women; however, it yielded no improvements in diabetes symptoms. While metformin reduced maternal weight gain, its effects on primary diabetes symptoms and other secondary outcomes like infant weight gain were mixed, indicating a need for further focused research to unravel these associations.

4 Oct 2023

Therapy News and Research

Blood test for pan-cancer biomarker could revolutionize early cancer detection

Researchers discover a vulnerability in immunotherapy-resistant triple-negative breast cancer

CRISPR gene editing study provides insights into how autism gene affects brain development

Automated insulin delivery could be a game-changer for pregnant women with type 1 diabetes

Psychedelic therapy shows promise for treating veterans with PTSD and brain injury

Unlocking the future of cancer care: Overcoming challenges in personalized neoantigen vaccine development

Optimized protocol to prevent disease transmission through maternal mitochondrial DNA carryover

The metabolic effects of endocrine therapy on diabetes mellitus in breast cancer survivors

Can falsified or substandard antimicrobials increase antimicrobial resistance?

Remote ischemic conditioning for acute stroke

Esketamine nasal spray superior in achieving remission in patients with treatment-resistant depression

New zebrafish xenograft platform could help screen for glioblastoma treatments

USC receives $2 million grant to advance cell and gene therapy research

Esketamine outperforms one of the standard drugs for treatment-resistant major depression

Study confirms accuracy of Vienna Prediction Model for venous thromboembolism

New workflow could significantly reduce wait time for urgent palliative radiation therapy

Experts to discuss if lasting remission from diabetes is feasible in real-world setting

Nearly half of the people with HIV, diabetes or hypertension in rural South Africa have unmet health needs

Measuring ctDNA may lead to alternative treatment options for BRAF wild-type melanoma

Early metformin therapy falls short in curbing gestational diabetes woes

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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