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LSD1 enzyme regulates skeletal muscle differentiation and metabolic activity

Our bodies convert food into energy for all life activities. These metabolic processes allow the cells that make up our bodies to produce (anabolism) and consume (catabolism) energy molecules from nutrients.

12 Apr 2018

Dietary fats play varied roles in disease

This month's issue of the Journal of Lipid Research features studies examining how fats in the diet affect health, including whether the ketogenic diet is a reasonable cancer therapy; how the type of unsaturated fats in a mouse's chow affects inflammation; and how cells respond to nutrient signals.

12 Apr 2018

Researchers discover key enzyme driving breast cancer

Looking to identify new strategies to prevent breast cancer recurrence, a research team led by Subhamoy Dasgupta, PhD, Assistant Professor of Oncology in the Department of Cell Stress Biology at Roswell Park Comprehensive Cancer Center, has identified two key proteins involved in glucose metabolism that could be targeted to prevent breast cancer metastasis and recurrence. The team's findings were published today in the journal Nature.

11 Apr 2018

Miniature injectable biosensor could offer continuous, long-term alcohol monitoring

Engineers at the University of California San Diego have developed a miniature, ultra-low power injectable biosensor that could be used for continuous, long-term alcohol monitoring.

11 Apr 2018

Research identifies link between rare gene variants and survival after blood and marrow transplant

Blood and marrow transplant, or BMT, is a lifesaving and effective treatment for many patients, but the procedure can cause serious and life-threatening complications.

10 Apr 2018

Researchers explore treatment target for acute kidney injury

When you have diabetes then get an acute kidney injury there is a multiplier effect that can worsen your prognosis and destroy your kidneys.

10 Apr 2018

New class of drug holds potential to help patients with treatment-resistant cancers

Researchers have discovered a new class of drug that has the potential to help cancer patients who no longer respond to existing therapies.

10 Apr 2018

Finding new drug target for common form of lung cancer

Research by Rutgers Cancer Institute of New Jersey investigators has identified novel functions of the superoxide dismutase 1 (SOD1) enzyme providing support that it could serve as a therapeutic target in the most common type of lung cancer.

10 Apr 2018

Bacteria that make high energy tiny carbon rings

Scientists have now bred bacteria that can create microscopic high energy carbon rings. This scientific breakthrough comes from Caltech scientists who have tweaked the enzymes of these bacteria in ways so that they can provide new molecular structures.

9 Apr 2018

Unexpected finding may play major role in deterring diabetic retinopathy

Diabetic retinopathy is considered one of the most disabling complications of diabetes and the leading cause of new cases of vision loss among adults.

6 Apr 2018

Researchers uncover mechanism critical to keeping blood stem cells functional

Hematopoietic stem cells, that form mature blood cells, require a very precise amount of protein to function - and defective regulation of protein production is common in certain types of aggressive human blood cancers.

6 Apr 2018

Study shows new health benefits in berry pigment

Naturally occurring pigments in berries, also known as anthocyanins, increase the function of the sirtuin 6 enzyme in cancer cells, a new study from the University of Eastern Finland shows. The regulation of this enzyme could open up new avenues for cancer treatment. The findings were published in Scientific Reports.

5 Apr 2018

Researchers find unexpected anti-inflammatory effects in PCSK9 inhibitors

PCSK9 inhibition is a new therapeutic strategy for atherosclerosis which is known to lower LDL cholesterol.

5 Apr 2018

New artificial enzyme uses visible light to kill bacteria

Researchers from RMIT University have developed a new artificial enzyme that uses light to kill bacteria.

5 Apr 2018

Two new studies highlight GABA's importance in type 1 and type 2 diabetes

Dynamic interactions between the nervous system, hormones and the immune system are normally on-going but in diabetes the balance is disturbed.

5 Apr 2018

Researchers reveal new tactic to fight antibiotic-resistant pneumonia

Antibiotic resistance is a growing threat in bacterial pneumonia. While immune-stimulating treatments can help the body kill the bacteria, they can also cause inflammation that damages and weakens lung tissue. Researchers at Boston Children's Hospital now describe an approach that offers the best of both worlds: enhanced bacterial killing with reduced lung damage.

4 Apr 2018

DNA-mimicking synthetic molecule could lead to new HIV treatment

Researchers have developed a synthetic compound that mimics the surface of DNA and is able to inhibit several DNA-processing enzymes.

4 Apr 2018

Obesity may have negative impact on liver health in children as young as 8 years old

A new study published today in The Journal of Pediatrics is the first to show that weight gain may have a negative impact on liver health in children as young as 8 years old. The study found that bigger waist circumference at age 3 raises the likelihood that by age 8, children will have markers for nonalcoholic fatty liver disease.

4 Apr 2018

Study finds high levels of hazardous chemicals in plastics collected from Lake Geneva

The first-ever chemical analysis of plastic collected from beaches around Lake Geneva detected cadmium, mercury and lead -- sometimes in very high concentrations that exceed the maximum permitted under EU law.

3 Apr 2018

New insights into 100-year-old mystery open novel possibilities for breast cancer treatment

New insights into how cancer cells fuel their growth are opening novel possibilities for cancer treatment. A team of researchers at Baylor College of Medicine and Roswell Park Comprehensive Cancer Center has identified a long sought after connection between how cancer cells use the sugar glucose to generate energy - the Warburg pathway - and cancer growth.

3 Apr 2018