Inflammation News and Research

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Novel biomarker can be used to identify disease progression in ALS

An international collaboration led by Flinders University has identified a potential biomarker for amyotrophic lateral sclerosis, also known as Motor Neuron Disease, providing a way to test the effectiveness of future clinical trials.

13 Jan 2022

Ultra-rapid genome sequencing technology can detect rare genetic diseases in eight hours

A new ultra-rapid genome sequencing approach developed by Stanford Medicine scientists and their collaborators was used to diagnose rare genetic diseases in an average of eight hours - a feat that's nearly unheard of in standard clinical care.

13 Jan 2022

Living alone, serial break-ups may raise the levels of inflammatory markers in men

Living alone for several years and/or experiencing serial relationship break-ups are strongly linked to raised levels of inflammatory markers in the blood-but only in men-finds a large population study published online in the Journal of Epidemiology & Community Health.

12 Jan 2022

Study finds a subset of vascular macrophages to be powerful ally in the fight against atherosclerosis

A new study reveals the existence of a powerful ally in the fight against cardiovascular disease, a protective subset of vascular macrophages expressing the C-type lectin receptor CLEC4A2, a molecule which fosters "good" macrophage behavior within the vessel wall.

11 Jan 2022

Study offers new evidence on how childhood immunometabolic risk factors may lead to depression, psychosis

A growing body of research suggests that early-life infection, inflammation, and metabolic changes could contribute to psychiatric disorders – perhaps via effects during critical periods of brain development.

11 Jan 2022

Adding a tomato concentrate to the diet can reduce intestinal inflammation related to HIV

New UCLA-led research in mice suggests that adding a certain type of tomato concentrate to the diet can reduce the intestinal inflammation that is associated with HIV. Left untreated, intestinal inflammation can accelerate arterial disease, which in turn can lead to heart attack and stroke.

11 Jan 2022

International study offers a clearer picture of COVID-19's impact on children

A new international study offers a clearer picture of the impact of COVID-19 infection and the risk of severe outcomes on young people around the world.

11 Jan 2022

Novel mechanism linking intercellular adhesion molecule with genetic skin diseases discovered

Northwestern Medicine investigators have discovered a novel mechanism linking an intercellular adhesion molecule with genetic inflammatory skin diseases, according to findings published in the Journal of Clinical Investigation.

11 Jan 2022

Unraveling the early host-immune response to SARS-CoV-2 in mild COVID-19 infections

In a new study, researchers determined the early immune response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) during mild coronavirus disease 2019 (COVID-19) in rhesus macaques.

11 Jan 2022

COVID-19 symptoms found to vary in different immune contexts

In a new study, researchers studied the kinetics of host response to SARS-CoV-2 infection in a Syrian hamster model, tracking disease pathology, viral loads, antibody responses, and inflammatory cytokine production in multiple organs.

11 Jan 2022

Development and validation of 2-gene host-based COVID-19 diagnostic classifiers

A group of researchers from Biohub has been attempting to create a more accurate method for PCR testing.

11 Jan 2022

Long-term exposure to air pollutants may increase the incidence of COVID-19

Long term exposure to ambient air pollution may heighten the risk of COVID-19 infection, suggests research published online in the journal Occupational & Environmental Medicine.

11 Jan 2022

SARS-CoV-2 activates microglia in the brain

Researchers demonstrate that SARS-CoV-2 can infect the human microglia.

10 Jan 2022

Immunological factors associated with impaired BNT162b2 mRNA vaccine response in older adults

A new study posted to the pre-print server medRxiv* investigated the significant immune alterations concerning SARS-CoV-2 specific innate and adaptive immunity associated with a lower BNT162b2 mRNA vaccine response in older individuals.

10 Jan 2022

Researchers create a DNA-based fluorescent nanoantenna to monitor the motions of proteins

Researchers at Université de Montréal have created a nanoantenna to monitor the motions of proteins. Reported this week in Nature Methods, the device is a new method to monitor the structural change of proteins over time – and may go a long way to helping scientists better understand natural and human-designed nanotechnologies.

10 Jan 2022

Biosimilars could drive down drug prices and lead to $38.4 billion savings

Biosimilar drugs could drive down prices for expensive medicines used to treat illnesses such as cancer and rheumatoid arthritis, with savings estimated to be $38.4 billion or 5.9% of projected total U.S. spending on biologics from 2021 to 2025, according to a new RAND Corporation study.

10 Jan 2022

Inflammation News and Research

Novel biomarker can be used to identify disease progression in ALS

Ultra-rapid genome sequencing technology can detect rare genetic diseases in eight hours

Living alone, serial break-ups may raise the levels of inflammatory markers in men

Study finds a subset of vascular macrophages to be powerful ally in the fight against atherosclerosis

Study offers new evidence on how childhood immunometabolic risk factors may lead to depression, psychosis

Adding a tomato concentrate to the diet can reduce intestinal inflammation related to HIV

International study offers a clearer picture of COVID-19's impact on children

Novel mechanism linking intercellular adhesion molecule with genetic skin diseases discovered

Unraveling the early host-immune response to SARS-CoV-2 in mild COVID-19 infections

COVID-19 symptoms found to vary in different immune contexts

Development and validation of 2-gene host-based COVID-19 diagnostic classifiers

Long-term exposure to air pollutants may increase the incidence of COVID-19

SARS-CoV-2 activates microglia in the brain

Immunological factors associated with impaired BNT162b2 mRNA vaccine response in older adults

Researchers create a DNA-based fluorescent nanoantenna to monitor the motions of proteins

Biosimilars could drive down drug prices and lead to $38.4 billion savings

Research may lead to new treatment options for Crohn's disease patients

Mice study shows how an antimicrobial found in toothpaste can trigger gut inflammation

Researchers identify factors at midlife linked with 10-year declines in women's physical health

Comparison of COVID-19 and influenza-associated complications

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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