Cancer Therapy News and Research

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Elderly lung cancer patients tolerate combined chemotherapy and radiotherapy with no higher risk of death than younger patients

Lung cancer remains the leading cause of cancer deaths in the U.S., with half of those diagnosed at age 70 years or older. About 20 percent of patients with lung cancer will have small cell lung cancer (SCLC). In the past, SCLC progressed rapidly despite initial chemotherapy sensitivity and few patients survive three years.

25 Apr 2005

Smad7 protein levels may predict prostate cancer therapy response

Levels of the Smad7 protein may predict therapeutic response in patients with prostate cancer according to research published by investigators at the Uppsala Branch of the Ludwig Institute for Cancer Research (LICR).

23 Apr 2005

Scientists have, for the first time, induced a state of reversible metabolic hibernation in mice

Scientists at Fred Hutchinson Cancer Research Center have, for the first time, induced a state of reversible metabolic hibernation in mice. This achievement, the first demonstration of "hibernation on demand" in a mammal, ultimately could lead to new ways to treat cancer and prevent injury and death from insufficient blood supply to organs and tissues.

23 Apr 2005

Using light under your skin

You have a tiny wound on your hand that doesn’t heal, a bad burn on your chest – or an injured retina. Your doctor cannot tell how serious the injuries are below the surface. He needs tissue samples. That means using a scalpel, which again equals pain, perhaps even a risk. Soon there may be hope for an improved and totally harmless method to peer under the surface of the skin: light.

23 Apr 2005

Mice put into "suspended animation" in U.S.

Researchers from the University of Washington and the Fred Hutchinson Cancer Research Centre in Seattle have placed mice in a state of near suspended animation, raising the possibility that in future hibernation could be induced in humans.

22 Apr 2005

Cancer patients may one day benefit from treatment with mixtures of customized antibodies

In a study published recently in the Proceedings of the National Academy of Sciences (USA), a team of Weizmann Institute scientists have demonstrated how the right combination might form a web that destroys the cancer cell's communication network, ultimately demobilizing the cell.

22 Apr 2005

Clinical study of MDX-010/MDX-1379 combination shows durable responses in patients with metastatic melanoma

Medarex, Inc. and Bristol-Myers Squibb Company announced today that complete or partial responses in seven of 56 patients with metastatic melanoma showed durability ranging from four months to the longest still ongoing at over 34 months, with five of the seven responses ongoing for more than two years.

20 Apr 2005

Reducing expression of a gene called BRCC36 makes breast cancer cells more responsive to ionizing radiation

The research was presented today at the 96th Annual Meeting of the American Association for Cancer Research (AACR) in Anaheim, Calif. BRCC36 directly interacts with the BRCA1 protein. Almost all invasive breast cancer cells have elevated BRCC36 levels compared to normal breast milk-duct cells.

20 Apr 2005

Selenium will have critical role in prostate cancer treatment

Researchers at Fox Chase Cancer Center in Philadelphia have come a step closer to understanding selenium's molecular role in causing prostate cancer cells to self-destruct. According to data presented today at the 96th Annual Meeting of the American Association for Cancer Research in Anaheim, Calif., selenium helps malignant cells overcome their resistance to TRAIL-induced apopstosis (self-inflicted cell death).

20 Apr 2005

New drug, RAD001, shown to stop the growth of ovarian cancer cells

A new drug, RAD001, has been shown to stop the growth and movement of certain ovarian cancer cells, according to scientists at Fox Chase Cancer Center in Philadelphia. The research was presented today at the 96th Annual Meeting of the American Association for Cancer Research (AACR) in Anaheim, Calif.

20 Apr 2005

Compound derived from cottonseed oil could help improve the effectiveness of chemotherapy at treating head and neck cancer

The findings, which will be presented Tuesday, April 19, at the American Association for Cancer Research annual meeting, could lead to a treatment that provides an effective option to surgically removing the cancer, helping patients preserve vital organs involved in speech and swallowing.

19 Apr 2005

Scientists identifiy protein that seems to control the malignant features of brain tumor cells

Scientists from Wake Forest University School of Medicine have identified a protein that seems to control the malignant features of brain tumor cells, suggesting a new treatment target for anti-cancer drugs. The research is reported in the current issue of Molecular Cancer Research.

13 Apr 2005

Race influences how we cope with cancer

White patients cope better with the pressure of cancer than their British Asian counterparts according to research published on-line in the British Journal of Cancer.

12 Apr 2005

Genetic testing could bolster radiotherapy's effectiveness against cancer

Obtaining a genetic picture of how a tumor will react to the many treatment techniques available could help doctors prescribe therapies customized for individual cancer patients' needs, suggests a Purdue University research team.

5 Apr 2005

Important trial in the fight against lung cancer

Two University of Kentucky researchers continue their work with a vaccine to prevent lung cancer recurrences in patients following primary treatment of the disease.

5 Apr 2005

Tarvacin shows significant anti-viral activity

Peregrine Pharmaceuticals today announced that there will be two presentations, April 4 and 6, at the American Association of Immunologists (AAI) annual meeting in San Diego, California, indicating the anti-viral potential of its Tarvacin antibody. Dr. Melina Soares of The University of Texas Southwestern Medical Center at Dallas will present pre-clinical data titled "Targeting inside-out phospholipids on viruses in a guinea pig model of Lassa fever."

4 Apr 2005

Men who are treated for prostate cancer with radiation may have almost doubled their risk of developing rectal cancer

A study in the American Gastroenterological Association (AGA) journal Gastroenterology has found that men who are treated for prostate cancer with radiation may have almost doubled their risk of developing rectal cancer when compared to men who opted to have surgery.

4 Apr 2005

Radiation for prostate cancer doubles the risk of developing rectal cancer

Men who undergo radiation for prostate cancer have nearly double the risk of developing rectal cancer when compared to men who opt to have surgery to treat prostate cancer, according to a study published today in the American Gastroenterological Association (AGA) journal Gastroenterology.

3 Apr 2005

Construction will enable pSivida to increase BrachySil production

Global nanotechnology company pSivida Limited has announced that it's UK manufacturing partner, Atomising Systems Ltd ("ASL"), has reached a key milestone in the manufacture of BrachySil, its lead product, by completing construction of a state of the art dedicated cleanroom facility to GMP specifications at its Sheffield plant in the United Kingdom. ASL is a world leader in high temperature atomising technology.

30 Mar 2005

First North American trial to evaluate the role of an aromatase inhibitor in the prevention of breast cancer

Today, a new clinical trial evaluating a novel approach to breast cancer prevention launched in the United States and Canada. Called the ExCel research study, this is the first North American clinical trial to evaluate the role of an aromatase inhibitor in the prevention of breast cancer.

30 Mar 2005

Cancer Therapy News and Research

Elderly lung cancer patients tolerate combined chemotherapy and radiotherapy with no higher risk of death than younger patients

Smad7 protein levels may predict prostate cancer therapy response

Scientists have, for the first time, induced a state of reversible metabolic hibernation in mice

Using light under your skin

Mice put into "suspended animation" in U.S.

Cancer patients may one day benefit from treatment with mixtures of customized antibodies

Clinical study of MDX-010/MDX-1379 combination shows durable responses in patients with metastatic melanoma

Reducing expression of a gene called BRCC36 makes breast cancer cells more responsive to ionizing radiation

Selenium will have critical role in prostate cancer treatment

New drug, RAD001, shown to stop the growth of ovarian cancer cells

Compound derived from cottonseed oil could help improve the effectiveness of chemotherapy at treating head and neck cancer

Scientists identifiy protein that seems to control the malignant features of brain tumor cells

Race influences how we cope with cancer

Genetic testing could bolster radiotherapy's effectiveness against cancer

Important trial in the fight against lung cancer

Tarvacin shows significant anti-viral activity

Men who are treated for prostate cancer with radiation may have almost doubled their risk of developing rectal cancer

Radiation for prostate cancer doubles the risk of developing rectal cancer

Construction will enable pSivida to increase BrachySil production

First North American trial to evaluate the role of an aromatase inhibitor in the prevention of breast cancer

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