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FDA seeks input from states on drug compounders

FDA Commissioner Margaret Hamburg convened a meeting that included federal officials and representatives from state boards of pharmacy and governors' offices. Meanwhile, the Los Angeles Times reports on "rogue pharmacists."

21 Dec 2012

Real estate businessman delivers $2.5M gift to University of Chicago Medicine for GI study

Real estate businessman Seymour "Sy" Taxman and his wife, Nancy, presented a gift of $2.5 million to the University of Chicago Medicine on Wednesday in honor of the late Joseph B. Kirsner, MD, PhD, the Louis Block Distinguished Service Professor of Medicine and a pioneer in the research and treatment of digestive disease.

21 Dec 2012

Surgeons make thousands of errors every year

So-called 'never events' happen more than 4,000 times a year, according to a study by Johns Hopkins researchers. Another report finds health care workers just as likely as people they treat to be overweight, avoid the dentist, get sunburned and not wear seatbelts.

21 Dec 2012

New MRI scans accurately measure damage to blood-brain barrier in stroke victims

Johns Hopkins researchers have developed a new way of looking at standard MRI scans that more accurately measures damage to the blood-brain barrier in stroke victims, a process they hope will lead to safer, more individualized treatment of blood clots in the brain and better outcomes.

21 Dec 2012

Updated U.S. prescribing information for Boehringer Ingelheim’s Pradaxa

Boehringer Ingelheim Pharmaceuticals, Inc. today announced that the U.S. prescribing information for Pradaxa (dabigatran etexilate mesylate) capsules was updated to include a contraindication related to use in patients with mechanical prosthetic heart valve replacement.

21 Dec 2012

Researchers reveal genetic basis for fundamental differences between humans and other vertebrates

University of Toronto Faculty of Medicine researchers have uncovered a genetic basis for fundamental differences between humans and other vertebrates that could also help explain why humans are susceptible to diseases not found in other species.

21 Dec 2012

NFKB gene variations could play a key role in helping to determine survival rate of sepsis patients

A study in the January 2013 issue of Anesthesiology offers evidence that variations in what is called the NFKB gene could play an important role in helping to determine the survival rate of patients who acquire sepsis, a condition in which the body is overwhelmed by infection, and which is the leading cause of death in hospitals.

21 Dec 2012

Addiction specialists co-edit new textbook to help Canadians stop smoking

Researchers from the University of Alberta are helping Canadian smokers butt out with a new textbook designed to give health professionals the right tools to treat tobacco addiction.

21 Dec 2012

Study examines role of race and ethnicity in stem cell donation

New research examining the role of race and ethnicity in an individual's decision to become a donor for hematopoietic cell transplantation (HCT) identifies several factors associated with varied participation rates in national donor registries across racial/ethnic groups. Results of this first-of-its-kind study are published online today in Blood, the Journal of the American Society of Hematology (ASH).

21 Dec 2012

Special supplement to Neurosurgery presents updates on emerging technologies for brain surgery

Robotic technologies have the potential to help neurosurgeons perform precise, technically demanding operations, together with virtual reality environments to help them navigate through the brain, according to a special supplement to Neurosurgery, official journal of the Congress of Neurological Surgeons.

21 Dec 2012

Melanoma patients may benefit from microRNA-26a replacement therapy

A University of Colorado Cancer Center study in this month's edition of the Journal of Investigative Dermatology describes a new target and potential treatment for melanoma, the most dangerous form of skin cancer. MicroRNA can decide which genes in a cell's DNA are expressed and which stay silent. Melanoma tends to lack microRNA-26a, which makes the gene SODD go silent.

21 Dec 2012

MiR-15 contributes to the heart's ability to regenerate following injury

UT Southwestern Medical Center researchers have pinpointed a molecular mechanism needed to unleash the heart's ability to regenerate, a critical step toward developing eventual therapies for damage suffered following a heart attack.

21 Dec 2012

Thickening of arterial walls causes branch retinal vein occlusion

Branch retinal vein occlusion - blockage of the blood vessels that channel blood from the retina - is a common eye disease. A type of blood clot in the eye, the disease causes reduced vision, and people with the disease also typically have an increased risk of hypertension, diabetes and other serious conditions. A young scientist from the University of Copenhagen has made a significant contribution to finding the cause of the disease.

21 Dec 2012

National Academy of Inventors names BMC dermatologist as 2012 Charter Fellow

Barbara Gilchrest, MD, professor and Chair Emeritus of the department of dermatology at Boston University School of Medicine (BUSM) and dermatologist at Boston Medical Center (BMC), has been named a 2012 Charter Fellow of the National Academy of Inventors (NAI). Gilchrest, a resident of Boston's North End, is among four faculty members at Boston University nominated to the NAI in 2012.

21 Dec 2012

New work on Akt's role in cancer stem cell biology

The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New work on Akt's role in cancer stem cell biology from the lab of senior author Honglin Zhou, MD, PhD and Weihua Li, co-first author, both from the Center for Resuscitation Sciences, Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, and Xiaowei Xu, Department of Pathology and Laboratory Medicine, appears in Molecular Cell.

21 Dec 2012

New technique to directly image biological structures at atomic levels

Investigators at the Virginia Tech Carilion Research Institute have invented a way to directly image biological structures at their most fundamental level and in their natural habitats. The technique is a major advancement toward the ultimate goal of imaging biological processes in action at the atomic level.

21 Dec 2012

Two recent experimental treatments improve visual function in mouse models of retinitis pigmentosa

Two recent experimental treatments - one involving skin-derived induced pluripotent stem (iPS) cell grafts, the other gene therapy - have been shown to produce long-term improvement in visual function in mouse models of retinitis pigmentosa (RP), according to the Columbia University Medical Center (CUMC) scientists who led the studies. At present, there is no cure for RP, the most common form of inherited blindness.

20 Dec 2012

Viewpoints: Could expanding mental health services curb gun violence?; Opinions on other aspects of health law

President Obama said he would use whatever powers his office holds to address this violence. ... Currently, nearly half of all gun sales in the U.S. are conducted without a background check. Criminals, the mentally ill, minors and domestic abusers are all prohibited from purchasing guns, but they all can do so as easily as attending a gun show or going online.

20 Dec 2012

Merck’s TREDAPTIVE clinical study on high-risk CVD patients does not meet primary endpoint

Merck, known outside the United States and Canada as MSD, today announced that the HPS2-THRIVE (Heart Protection Study 2-Treatment of HDL to Reduce the Incidence of Vascular Events) study of TREDAPTIVE(extended-release niacin/laropiprant) did not meet its primary endpoint.

20 Dec 2012

Proteins detected in urine may enable diagnosis of Kawasaki disease

A set of proteins detected in urine by researchers at Boston Children's Hospital may prove to be the first biomarkers for Kawasaki disease, an uncommon but increasingly prevalent disease which causes inflammation of blood vessels that can lead to enlarged coronary arteries and even heart attacks in some children.

20 Dec 2012

Medicine News and Research

FDA seeks input from states on drug compounders

Real estate businessman delivers $2.5M gift to University of Chicago Medicine for GI study

Surgeons make thousands of errors every year

New MRI scans accurately measure damage to blood-brain barrier in stroke victims

Updated U.S. prescribing information for Boehringer Ingelheim’s Pradaxa

Researchers reveal genetic basis for fundamental differences between humans and other vertebrates

NFKB gene variations could play a key role in helping to determine survival rate of sepsis patients

Addiction specialists co-edit new textbook to help Canadians stop smoking

Study examines role of race and ethnicity in stem cell donation

Special supplement to Neurosurgery presents updates on emerging technologies for brain surgery

Melanoma patients may benefit from microRNA-26a replacement therapy

MiR-15 contributes to the heart's ability to regenerate following injury

Thickening of arterial walls causes branch retinal vein occlusion

National Academy of Inventors names BMC dermatologist as 2012 Charter Fellow

New work on Akt's role in cancer stem cell biology

New technique to directly image biological structures at atomic levels

Two recent experimental treatments improve visual function in mouse models of retinitis pigmentosa

Viewpoints: Could expanding mental health services curb gun violence?; Opinions on other aspects of health law

Merck’s TREDAPTIVE clinical study on high-risk CVD patients does not meet primary endpoint

Proteins detected in urine may enable diagnosis of Kawasaki disease

Everything there is to know about biosimilars eBook

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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