Immune Response News and Research

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NEI-funded research aims to prevent or reverse progression of cataracts

Research funded by the National Eye Institute aims to reverse progression of cataracts- the most common cause of blindness worldwide- or to prevent them from forming altogether.

30 Jun 2017

Scientists find new clues to how RSV causes disease

By age 2, most children have been infected with respiratory syncytial virus (RSV), which usually causes only mild cold symptoms. But people with weakened immune systems, such as infants and the elderly, can face serious complications, including pneumonia and -- in some cases -- death.

30 Jun 2017

Proteins impeding antitumor immunity could be 'Achilles heel' of some cancers

By comparing variations in protein expression in tumor samples from a single melanoma patient, researchers from the Johns Hopkins Bloomberg~Kimmel Institute and the Memorial Sloan-Kettering Cancer Center say their findings have the potential to reveal some of the mechanisms underlying response or resistance to immunotherapy drugs.

28 Jun 2017

Study: Postponing lymph node biopsy after melanoma diagnosis does not affect long-term outcomes

Postponing lymph node biopsy more than 30 days after melanoma diagnosis doesn't adversely impact long-term clinical outcomes, according to new study findings published online as an "article in press" on the Journal of the American College of Surgeons website ahead of print publication.

28 Jun 2017

Study develops dissolvable microneedle patches for administering influenza vaccine

Study findings published online in The Lancet on June 27, 2017 have found that an experimental patch of dissolving microneedles can produce robust immune responses for influenza. The microneedle patches can be administered safely and can be a substitute for the needle-and-syringe vaccination. With further advancements, they could remove the uneasiness in using an injection and inconvenience of visiting a flu clinic, as well as offering cost benefits.

28 Jun 2017

New cranberry derivative could help patients dependent on tube feeding

Synesis, a University of Wisconsin-Madison spinoff developing a patented formula for liquid nutrition, is advancing a plant-based additive designed to reduce or eliminate severe side effects of tube feeding.

28 Jun 2017

Bandage-strip sized microneedle patches can transform flu vaccination method

A National Institutes of Health-funded study led by a team at the Georgia Institute of Technology and Emory University has shown that an influenza vaccine can produce robust immune responses and be administered safely with an experimental patch of dissolving microneedles.

28 Jun 2017

Study finds link between upper GI infections and protein implicated in Parkinson’s disease

Acute and chronic infections in a person's upper gastrointestinal tract appear to be linked to Parkinson's disease, say scientists at Georgetown University Medical Center and their collaborators at the National Institutes of Health and other institutions.

28 Jun 2017

Four-food elimination diet can resolve symptoms of eosinophilic esophagitis in children

Children with eosinophilic esophagitis (EoE) – a chronic inflammatory disease that injures the esophagus – who temporarily eliminated cow's milk, wheat, egg and soy from their diet for eight weeks had their symptoms and esophageal swelling resolve, according to a study published in Clinical Gastroenterology and Hepatology.

27 Jun 2017

Researchers study Lassa fever patient's immune response and viral persistence

When an American nurse working in West Africa became ill with Lassa fever and was evacuated to the U.S. for treatment in 2016, it provided a rare opportunity.

22 Jun 2017

Microscopic fungus exacerbates Crohn's disease symptoms, mice study shows

A microscopic fungus called Candida tropicalis triggered gut inflammation and exacerbated symptoms of Crohn's disease, in a recent study conducted at Case Western Reserve University School of Medicine.

22 Jun 2017

Scientists develop new algorithm to decipher how immune system recognizes and binds antigens

Scientists from St. Jude Children's Research Hospital and Fred Hutchinson Cancer Research Center have developed an algorithm that functions like a Rosetta Stone to help decipher how the immune system recognizes and binds antigens.

22 Jun 2017

Scientists discover biological fingerprint in children with tuberculosis meningitis

Children with tuberculosis meningitis - a brain and spinal cord infection that leads to disability and death -- have a biological fingerprint that can be used to assess the severity of the condition, help decide the best course of treatment, and provide clues for novel treatments, scientists at the Francis Crick Institute, Imperial College London and the University of Cape Town reveal.

21 Jun 2017

Researchers find new evidence that autoimmunity plays role in Parkinson's disease

Researchers have found the first direct evidence that autoimmunity- in which the immune system attacks the body's own tissues- plays a role in Parkinson's disease, the neurodegenerative movement disorder.

21 Jun 2017

Combination of immunotherapies effective against mouse model of rhabdomyosarcoma

Rhabdomyosarcoma, a cancer made up of cells that normally develop into skeletal muscles, is the most common soft tissue cancer in children. If it is detected early and localized in certain areas, rhabdomyosarcoma is usually curable with traditional therapies like surgery, radiation, and chemotherapy.

20 Jun 2017

Researchers show effective oral treatment option for patients with rheumatoid arthritis

Patients suffering from rheumatoid arthritis are treated for around six months with the standard anti-rheumatic agent methotrexate, to which many patients respond very well.

19 Jun 2017

Viral vectors for gene transfer can travel to distant areas in the brain, study shows

Gene transfer is seen as a hopeful therapy for Alzheimer's and Parkinson's patients. The approach involves using harmless laboratory-produced viruses to introduce important genes into the brain cells.

16 Jun 2017

Wayne State awarded NIH grant to identify new therapeutic targets for bacterial keratitis

Wayne State University recently received a five-year, $1.925 million grant from the National Eye Institute of the National Institutes of Health to test the role of microRNAs (miRNAs) - a newly recognized level of gene expression regulation - in bacterial keratitis – an infection of the cornea caused by bacteria - as well as to identify new therapeutic targets and alternative treatment strategies.

15 Jun 2017

Targeting regulatory T cells could be effective approach to treating cancers, research shows

Researchers at University of Pittsburgh School of Medicine and UPMC have discovered a clue that could unlock the potential of immunotherapy drugs to successfully treat more cancers.

15 Jun 2017

Researchers use quantum dots to decipher design features for new therapies aimed at MS

Researchers in the University of Maryland Fischell Department of Bioengineering (BIOE) Jewell Laboratory are using quantum dots - tiny semiconductor particles commonly used in nanotechnology - to decipher the features needed to design specific and effective therapies for multiple sclerosis (MS) and other autoimmune diseases.

14 Jun 2017

Immune Response News and Research

NEI-funded research aims to prevent or reverse progression of cataracts

Scientists find new clues to how RSV causes disease

Proteins impeding antitumor immunity could be 'Achilles heel' of some cancers

Study: Postponing lymph node biopsy after melanoma diagnosis does not affect long-term outcomes

Study develops dissolvable microneedle patches for administering influenza vaccine

New cranberry derivative could help patients dependent on tube feeding

Bandage-strip sized microneedle patches can transform flu vaccination method

Study finds link between upper GI infections and protein implicated in Parkinson’s disease

Four-food elimination diet can resolve symptoms of eosinophilic esophagitis in children

Researchers study Lassa fever patient's immune response and viral persistence

Microscopic fungus exacerbates Crohn's disease symptoms, mice study shows

Scientists develop new algorithm to decipher how immune system recognizes and binds antigens

Scientists discover biological fingerprint in children with tuberculosis meningitis

Researchers find new evidence that autoimmunity plays role in Parkinson's disease

Combination of immunotherapies effective against mouse model of rhabdomyosarcoma

Researchers show effective oral treatment option for patients with rheumatoid arthritis

Viral vectors for gene transfer can travel to distant areas in the brain, study shows

Wayne State awarded NIH grant to identify new therapeutic targets for bacterial keratitis

Targeting regulatory T cells could be effective approach to treating cancers, research shows

Researchers use quantum dots to decipher design features for new therapies aimed at MS

Understanding the DNA Damage Response in Innate Immunity eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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