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CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

Researchers utilize the CRISPR-Cas9 system to induce the synthesis of dopamine (DA) in the brains of a rat model for Parkinson’s disease.

11 Aug 2023

Personalized exercise testing may be more effective for fat loss

The best heart rate for burning fat differs for each individual and often does not align with the "fat burning zone" on commercial exercise machines, Icahn School of Medicine at Mount Sinai researchers report.

11 Aug 2023

Using ultrasound and AI to investigate the characteristics and healing trajectory of burn wounds

To provide the best care for injured service members, combat medics need reliable tools. To develop better tools, they call upon engineers.

11 Aug 2023

Study explores the use of existing medicines to revolutionize cancer treatment

In a recent study published in the journal of Genes & Diseases, Research team led by Lu explores the potential for the use of FDA-approved hypertension and EMA-approved cough medicines to revolutionize cancer treatment.

10 Aug 2023

Machine learning can accurately predict subtypes of Parkinson's disease

Researchers at the Francis Crick Institute and UCL Queen Square Institute of Neurology, working with technology company Faculty AI, have shown that machine learning can accurately predict subtypes of Parkinson's disease using images of patient-derived stem cells.

10 Aug 2023

Ovarian cancer patients enrolled in first-in-human trial of CAR T cell therapy

Recently published preclinical data by City of Hope scientists shows the immunotherapy is effective. Advanced ovarian cancer patients are now being enrolled in a Phase 1 first-in-human trial.

10 Aug 2023

New gene-editing tool helps to study single-base mutations in cancer

A change in just one letter in the code that makes up a cancer-causing gene can significantly affect how aggressive a tumor is or how well a patient with cancer responds to a particular therapy.

10 Aug 2023

Scientists develop "universal pan-mammalian clock" to accurately estimate age in mammals

Scientists at UCLA David Geffen School of Medicine and UCLA Health led an international research team that published two articles detailing changes in DNA – changes that researchers found are shared by humans and other mammals throughout history and are associated with life span and numerous other traits.

10 Aug 2023

Tiny particles made from red blood cells may treat atherosclerosis and other diseases

Atherosclerosis is a disease in which fat, cholesterol, and other substances build up inside artery walls. This can lead to plaque formation, which can block arteries and cause heart attacks and strokes.

10 Aug 2023

Experimental drug can reduce symptoms of inflammatory bowel disease in pre-clinical models

A new study of mice and lab-grown human colon "organoids" indicates that an experimental drug developed by Johns Hopkins Medicine researchers can substantially reduce symptoms of inflammatory bowel disease (IBD) in pre-clinical models.

10 Aug 2023

Autism spectrum disorder may be linked to imbalance of neurons in the brain

Using human "mini-brain" models known as organoids, Mayo Clinic and Yale University scientists have discovered that the roots of autism spectrum disorder may be associated with an imbalance of specific neurons that play a critical role in how the brain communicates and functions.

10 Aug 2023

AI-powered system shows promise in speeding up endometriosis diagnosis

The quality of life of millions suffering from endometriosis - a painful disease where sensitive tissue grows outside of the uterus - could be improved by a new artificial intelligence (AI) system with technology developed by the University of Adelaide in South Australia, in partnership with researchers from the University of Surrey.

10 Aug 2023

Optilume BPH Catheter System offers a safe and effective treatment for benign prostatic hyperplasia

Treatment with the recently approved, minimally invasive Optilume BPH device improves urinary symptoms while preserving sexual function in men with benign prostatic hyperplasia (BPH), concludes a randomized trial in the September issue of The Journal of Urology®, an Official Journal of the American Urological Association (AUA).

10 Aug 2023

Novel technology can diagnose immunothrombosis by measuring thrombin activity through breath gas

Immunothrombosis, or the formation of microscopic blood clots during inflammation, is a major cause of morbidity among patients with sepsis or severe COVID-19.

10 Aug 2023

New pathway for HIV to enter nucleus of healthy cells identified

A study published on August 10, 2023 in the journal Nature Communications has identified a new pathway that human immune deficiency virus (HIV) uses to enter the nucleus of a healthy cell, where it can then replicate and go on to invade other cells.

10 Aug 2023

Ensuring colony counts remain precise and verifiable using a completely automated colony counting system

In this interview, NewsMedical speaks with Richard Edridge, Synbiosis Projects and Sales Manager for Synoptics, about AutoCOL, a completely automated colony counting system for fully traceable colony counts with every use.

From Synoptics Ltd 10 Aug 2023

MaxCyte signs strategic platform license with Lyell Immunopharma

From MaxCyte, Inc. 10 Aug 2023

MaxCyte and Vittoria Biotherapeutics sign strategic platform license to advance next generation cellular therapies

MaxCyte, Inc., a leading, cell-engineering focused company providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell-based therapeutics and to support innovative, cell-based research, and Vittoria Biotherapeutics (Vittoria), a leading edge, gene-edited cell therapeutics company with novel platform technologies poised to develop a pipeline of highly differentiated cellular therapies for both oncology and immunology indications, today announced the signing of a strategic platform license (SPL) of MaxCyte’s Flow Electroporation® technology and ExPERT™ platform to Vittoria Biotherapeutics.

From MaxCyte, Inc. 10 Aug 2023

MaxCyte signs strategic platform license with prime medicine to advance next-generation gene editing therapies for patients

From MaxCyte, Inc. 10 Aug 2023

Fruit fly study provides insights into piRNA production and fertility

You're likely familiar with RNA, the molecule that plays an important role in protein production and gene expression control.

9 Aug 2023

Technology News and Research

CRISPR/sgRNA-SAM therapy: a potential breakthrough for Parkinson's disease?

Personalized exercise testing may be more effective for fat loss

Using ultrasound and AI to investigate the characteristics and healing trajectory of burn wounds

Study explores the use of existing medicines to revolutionize cancer treatment

Machine learning can accurately predict subtypes of Parkinson's disease

Ovarian cancer patients enrolled in first-in-human trial of CAR T cell therapy

New gene-editing tool helps to study single-base mutations in cancer

Scientists develop "universal pan-mammalian clock" to accurately estimate age in mammals

Tiny particles made from red blood cells may treat atherosclerosis and other diseases

Experimental drug can reduce symptoms of inflammatory bowel disease in pre-clinical models

Autism spectrum disorder may be linked to imbalance of neurons in the brain

AI-powered system shows promise in speeding up endometriosis diagnosis

Optilume BPH Catheter System offers a safe and effective treatment for benign prostatic hyperplasia

Novel technology can diagnose immunothrombosis by measuring thrombin activity through breath gas

New pathway for HIV to enter nucleus of healthy cells identified

Ensuring colony counts remain precise and verifiable using a completely automated colony counting system

MaxCyte signs strategic platform license with Lyell Immunopharma

MaxCyte and Vittoria Biotherapeutics sign strategic platform license to advance next generation cellular therapies

MaxCyte signs strategic platform license with prime medicine to advance next-generation gene editing therapies for patients

Fruit fly study provides insights into piRNA production and fertility

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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