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UMMC transplant team performs second pig heart transplant on patient with end-stage heart disease

After world's first successful transplant in 2022, also performed at the University of Maryland Medical Center (UMMC), this groundbreaking transplant team performed second pig heart transplant on patient deemed ineligible for traditional heart transplant.

25 Sep 2023

Finnish study finds revised dementia guidelines did not reduce psychotropic use

A recent register-based study examined the impact of Finland's revised clinical guidelines for the treatment of dementia, published in 2017, on the trend of users of psychotropics in older people with dementia in 2009-2020.

25 Sep 2023

Once-weekly ALTUVIIIO® approved in Japan as a new class of factor VIII therapy for hemophilia A

The Japanese Ministry of Health, Labor, and Welfare (MHLW) has granted marketing authorization for ALTUVIIIO.

From Sanofi 25 Sep 2023

AI-Doctor's accuracy in retinal disease detection redefines medical diagnosis

An advanced artificial Intelligence (AI) system designed to interpret fundus fluorescein angiography (FFA) images precisely.

25 Sep 2023

Long-term consumption of ultra-processed foods may increase depression risk

The effects of ultra-processed food (UPF) on mental health.

25 Sep 2023

Could metformin be a game changer for heart health in non-diabetics?

Using Mendelian randomization, researchers found that altering seven metformin targets led to improved blood pressure and BMI in non-diabetic individuals. The study suggests the potential for metformin's role in reducing cardiovascular risks in the general population, although more research is needed.

24 Sep 2023

Exercise boosts immune defense in Lynch syndrome patients

Aerobic exercise, specifically cycling, shows promise in reducing inflammation and boosting immune responses in the colonic tissue of Lynch syndrome patients, a group at high risk for colorectal cancer. The study suggests that regular exercise may offer a preventive approach for this patient population, though further randomized trials are needed.

24 Sep 2023

Mechanoresilient cancer cells more prone to metastasis

The ability of cancer cells to metastasize, or spread from one part of the body to another, is one of the reasons why cancer can be extremely challenging to treat.

22 Sep 2023

Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials

Tumor vaccines can help the body fight cancer. These vaccines alert the patient's immune system to proteins that are carrying cancer-typical alterations.

22 Sep 2023

Researchers find a promising drug candidate for the treatment of ALS

A research group at the University of Helsinki and its partners have found a promising drug candidate for the treatment of amyotrophic lateral sclerosis (ALS).

22 Sep 2023

Using kinase inhibitors in subsets of colorectal cancer patients

A new editorial paper was published in Oncoscience (Volume 10) on June 27, 2023, entitled, "Kinase-targeted therapy in subsets of colorectal cancer."

22 Sep 2023

Researchers develop novel ultrasound imaging technique to view macrophages in real time

Macrophages are little cells vital to the immune system and could possibly inform cell-based therapies for a variety of medical conditions.

22 Sep 2023

New science committee to support One Medicine research at Humanimal Trust

Humanimal Trust, the charity founded in 2014 by orthopaedic veterinary surgeon, Professor Noel Fitzpatrick, has announced a new Committee of independent advisors, made up of leading human and animal health professionals, academics and researchers from around the world.

22 Sep 2023

Inhaled fluticasone furoate falls flat in speeding up COVID-19 recovery, says ACTIV-6 trial

The ACTIV-6 trial investigated the effectiveness of inhaled fluticasone furoate on mild-to-moderate COVID-19 cases and found it did not accelerate recovery or prevent clinical progression compared to a placebo. Interestingly, vaccinated participants showed slightly faster recovery when treated with the drug, while unvaccinated participants did not.

21 Sep 2023

Multipronged gene therapy restores walking in mice after complete spinal cord injury

When the spinal cords of mice and humans are partially damaged, the initial paralysis is followed by the extensive, spontaneous recovery of motor function.

21 Sep 2023

Pitt launches trial to test interventions for life-threatening bleeding in injured children

The No. 1 cause of death in children is trauma. There are an estimated 2,000 pediatric deaths from traumatic bleeding in the U.S. each year that are preventable with optimal care, yet there have been no large-scale clinical trials to guide the best way to resuscitate children with life-threatening bleeding from traumatic injury.

21 Sep 2023

AI slashes stroke treatment time and saves lives in new study

AI-driven software significantly speeds up the detection of large vessel occlusion in stroke patients, reducing treatment time and potentially improving outcomes. The automated system was linked to a 60% drop in mortality rates in a clinical trial across four comprehensive stroke centers.

21 Sep 2023

Clinical trial hopes to enhance treatment options for women with lethal gynecological cancers

An international clinical trial exploring a new way to treat rare and aggressive gynaecological cancers has launched in Melbourne.

21 Sep 2023

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

A comprehensive review in Signal Transduction and Targeted Therapy delves into the versatility and effectiveness of mRNA vaccines, from their game-changing role in COVID-19 to potential applications in cancer and rare diseases. Despite drawbacks like stability and high immunogenicity, advancements in vaccine technology have poised mRNA platforms as a robust tool for both preventive and therapeutic interventions.

21 Sep 2023

ACT and personalized cancer vaccine combo shows efficacy in ovarian cancer patients

A Ludwig Cancer Research study has shown that combining adoptive T cell therapy (ACT) with an innovative, personalized cancer vaccine under development at the Lausanne Branch of the Ludwig Institute for Cancer Research can benefit patients with late-stage, drug-resistant ovarian cancer.

21 Sep 2023

Therapy News and Research

UMMC transplant team performs second pig heart transplant on patient with end-stage heart disease

Finnish study finds revised dementia guidelines did not reduce psychotropic use

Once-weekly ALTUVIIIO® approved in Japan as a new class of factor VIII therapy for hemophilia A

AI-Doctor's accuracy in retinal disease detection redefines medical diagnosis

Long-term consumption of ultra-processed foods may increase depression risk

Could metformin be a game changer for heart health in non-diabetics?

Exercise boosts immune defense in Lynch syndrome patients

Mechanoresilient cancer cells more prone to metastasis

Peptide vaccine targets H3K27M mutation in midline gliomas, shows promise in early trials

Researchers find a promising drug candidate for the treatment of ALS

Using kinase inhibitors in subsets of colorectal cancer patients

Researchers develop novel ultrasound imaging technique to view macrophages in real time

New science committee to support One Medicine research at Humanimal Trust

Inhaled fluticasone furoate falls flat in speeding up COVID-19 recovery, says ACTIV-6 trial

Multipronged gene therapy restores walking in mice after complete spinal cord injury

Pitt launches trial to test interventions for life-threatening bleeding in injured children

AI slashes stroke treatment time and saves lives in new study

Clinical trial hopes to enhance treatment options for women with lethal gynecological cancers

Unlocking the power of mRNA vaccines: From COVID-19 to cancer and beyond

ACT and personalized cancer vaccine combo shows efficacy in ovarian cancer patients

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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