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Gender bias detected for hip arthroplasty failure

Women are significantly more likely than men to experience implant failure after primary total hip arthroplasty, suggests research published in JAMA Internal Medicine.

25 Feb 2013

C-section babies more likely to develop allergies

For expectant moms who may contemplate the pros and cons of natural child birth or Caesarian section, a Henry Ford Hospital study suggests that C-section babies are susceptible to developing allergies by age two.

25 Feb 2013

Systemic delivery of antisense oligonucleotides neutralizes mutant RNA toxicity in mice with DM1

By targeting the specific mutation that causes the hereditary neuromuscular disease myotonic dystrophy, it is possible to neutralize the mutant RNA toxicity and minimize or even eliminate the disabling symptoms of the disease.

25 Feb 2013

Researchers identify several genes associated with human neurological disorders

Scientists at the Marine Biological Laboratory (MBL) have identified several genes linked to human neurological disorders, including Alzheimer's disease, Parkinson's disease and spinal cord injury, in the sea lamprey, a vertebrate fish whose whole-genome sequence is reported this week in the journal Nature Genetics.

25 Feb 2013

Familial Hypercholesterolaemia patients often inherit small-effect changes in several genes rather than a large-effect mutation in a single gene

Research published Online First in The Lancet provides new evidence that a substantial proportion of individuals with a clinical diagnosis of Familial Hypercholesterolaemia (FH) inherit a combination of small-effect changes in several genes (polygenic) rather than a large-effect mutation in a single gene (monogenic).

22 Feb 2013

Research into why young adults overuse short-acting bronchodilators

The high cost of medication, stigmatisation and poor acceptance of their condition are causing young adults to take a dangerous approach to managing their asthma, according to new research published today in the journal BMJ Open.

22 Feb 2013

Oral polio vaccine cold chain disruption in Pakistan could compromise immunization effectiveness, health officials warn

Health officials in Pakistan have formally complained to the WHO concerning the quality of oral polio vaccine (OPV) doses distributed by the U.N. body," SciDev.Net reports, noting 58 children became infected with polio in 2012 despite having received the vaccine.

22 Feb 2013

Intense Facebook use might have positive effect on psychological well-being

A recent study in Behaviour & Information Technology investigated the role Facebook use plays in the creation or maintenance of social capital among 800 students from 7 universities in South Africa. Empirical research has linked social capital to many positives in society, such as improved mental and physical health and economic well-being.

22 Feb 2013

People with increased genetic risk of schizophrenia more likely to have lower IQs at age 70

People who are at greater genetic risk of schizophrenia are more likely to see a fall in IQ as they age, even if they do not develop the condition. Scientists at the University of Edinburgh say the findings could lead to new research into how different genes for schizophrenia affect brain function over time.

22 Feb 2013

Viewpoints: Holtz-Eakin and Roy offer prescription to fix health law; Iowa lawmakers opposed to Medicaid expansion should give up their coverage

Over nearly a century, progressives have pressed for a national, single-payer healthcare system. When it comes to health reform, what have conservatives stood for? For far too long, conservatives have failed to coalesce around a long-term vision of what a free-market healthcare system should look like. ... Obamacare is the logical byproduct of this conservative policy neglect.

22 Feb 2013

Researchers identify second B-cell attachment receptor for Epstein-Barr virus

Epstein-Barr virus (EBV) affects more than 90 percent of the population worldwide and was the first human virus found to be associated with cancer. Now, researchers from Beth Israel Deaconess Medical Center (BIDMC) have broadened the understanding of this widespread infection with their discovery of a second B-cell attachment receptor for EBV.

21 Feb 2013

Microbubble-ultrasound method improves cardiac output after heart attack

Scientists from the Bonn University Hospital successfully tested a method in mice allowing the morphological and functional sequelae of a myocardial infarction to be reduced. Tiny gas bubbles are made to oscillate within the heart via focused ultrasound - this improves microcirculation and decreases the size of the scar tissue. The results show that the mice, following myocardial infarction, have improved cardiac output as a result of this method, as compared to untreated animals.

21 Feb 2013

Bariatric surgery does not lower overall health care costs linked with obesity

Bariatric surgery is a well-documented treatment for obesity that leads to considerable weight loss and health improvement, but is the surgery successful in the long run in reducing costs associated with medical care for obesity? A team of researchers from the Johns Hopkins Bloomberg School of Public Health and School of Medicine recently undertook a multi-year analysis of health insurance claims data to examine this question and found that although the procedure's success rate is well documented, it does not have a similar impact on health care costs.

21 Feb 2013

Cancer genetics pioneer, Bert Vogelstein, awarded the Breakthrough Prize in Life Sciences

Bert Vogelstein, M.D., co-director of the Ludwig Center at Johns Hopkins and a Howard Hughes Medical Institute investigator has been awarded the Breakthrough Prize in Life Sciences. He was selected for his landmark work in cancer genomics and tumor suppressor genes.

21 Feb 2013

Selenium supplements and heart disease risk: an interview with Dr Saverio Stranges, University of Warwick

Selenium is a micronutrient which has antioxidant properties by means of selenoproteins which play many important functions in the body. They actually are contained in many different foods. The amount of selenium we get from diet is closely linked to the amount of selenium in the soil.

21 Feb 2013

Article provides examples of how epigenetic drug treatments could be beneficial in treating cancers

A review article by researchers at Boston University School of Medicine (BUSM) proposes a new epigenetic hypothesis linked to tumor production and novel ideas about what causes progenitor cells to develop into cancer cells. Published in the February 2013 issue of Epigenomics, the article provides examples of how epigenetic drug treatments could be beneficial in treating cancers while also decreasing the likelihood of cancer relapse.

21 Feb 2013

Osteopontin plays a role in X-linked hypophosphatemia

Diagnosed in toddlers, X-linked hypophosphatemia (XLH) is the most common form of heritable rickets, in which soft bones bend and deform, and tooth abscesses develop because infections penetrate soft teeth that are not properly calcified. Researchers at McGill University and the Federal University of Sao Paulo have identified that osteopontin, a major bone and tooth substrate protein, plays a role in XLH. Their discovery may pave the way to effectively treating this rare disease.

21 Feb 2013

Signaling pathway might determine genetic susceptibility for fetal alcohol spectrum disorder

Fetal alcohol syndrome is the leading preventable cause of developmental disorders in developed countries. And fetal alcohol spectrum disorder (FASD), a range of alcohol-related birth defects that includes fetal alcohol syndrome, is thought to affect as many as 1 in 100 children born in the United States.

21 Feb 2013

Four genetic variations may increase risk of colorectal cancer

An international research team co-led by cancer prevention researcher Ulrike "Riki" Peters, Ph.D., M.P.H., and biostatistician Hsu Li, Ph.D., at Fred Hutchinson Cancer Research Center has identified variations in four genes that are linked to an increased risk of colorectal cancer.

21 Feb 2013

Symptom severity, hospice patient distress not necessarily linked

End-stage heart failure patients being treated in hospices have multiple symptoms with potential to cause distress, indicate US study findings.

20 Feb 2013

X linked News and Research

Gender bias detected for hip arthroplasty failure

C-section babies more likely to develop allergies

Systemic delivery of antisense oligonucleotides neutralizes mutant RNA toxicity in mice with DM1

Researchers identify several genes associated with human neurological disorders

Familial Hypercholesterolaemia patients often inherit small-effect changes in several genes rather than a large-effect mutation in a single gene

Research into why young adults overuse short-acting bronchodilators

Oral polio vaccine cold chain disruption in Pakistan could compromise immunization effectiveness, health officials warn

Intense Facebook use might have positive effect on psychological well-being

People with increased genetic risk of schizophrenia more likely to have lower IQs at age 70

Viewpoints: Holtz-Eakin and Roy offer prescription to fix health law; Iowa lawmakers opposed to Medicaid expansion should give up their coverage

Researchers identify second B-cell attachment receptor for Epstein-Barr virus

Microbubble-ultrasound method improves cardiac output after heart attack

Bariatric surgery does not lower overall health care costs linked with obesity

Cancer genetics pioneer, Bert Vogelstein, awarded the Breakthrough Prize in Life Sciences

Selenium supplements and heart disease risk: an interview with Dr Saverio Stranges, University of Warwick

Article provides examples of how epigenetic drug treatments could be beneficial in treating cancers

Osteopontin plays a role in X-linked hypophosphatemia

Signaling pathway might determine genetic susceptibility for fetal alcohol spectrum disorder

Four genetic variations may increase risk of colorectal cancer

Symptom severity, hospice patient distress not necessarily linked

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