Brain Tumor News and Research

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A Brain Tumor is the growth of abnormal cells in the tissues of the brain. Brain tumors can be benign (not cancer) or malignant (cancer).

Genetic biomarker can help predict survival outcomes in patients with certain gliomas

A DNA-level biomarker (MGMT promoter methylation) can be used to help predict survival outcomes in patients with high-risk, low-grade gliomas, according to a new study conducted through the NRG Oncology/RTOG collaborative clinical trials group and led by scientists at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

28 Jun 2018

Polio virus could help brain cancer patients

According to researchers genetically altered poliovirus strains could help some patients of brain cancer. A team of researchers from Duke University in Durham, North Carolina, used modified polio virus strains in small groups of patients who had glioblastoma – a particularly deadly form of brain cancer. In these patients standard treatments have failed say the researchers and this novel therapy could help.

27 Jun 2018

Phase 1 clinical trial of poliovirus therapy shows long-term survival benefit for recurrent glioblastoma

A genetically modified poliovirus therapy developed at Duke Cancer Institute shows significantly improved long-term survival for patients with recurrent glioblastoma, with a three-year survival rate of 21 percent in a phase 1 clinical trial.

26 Jun 2018

Unusual cell-to-cell communication in glioblastoma promotes aggressiveness and therapy resistance

A surprising form of cell-to-cell communication in glioblastoma promotes global changes in recipient cells, including aggressiveness, motility, and resistance to radiation or chemotherapy.

22 Jun 2018

Targeting cells involved in blood vessel formation could hinder brain tumor growth

A type of highly malignant brain tumor contains a large number of cells involved in the formation of new blood vessels, helping it proliferate and spread.

20 Jun 2018

Scientists point to potentially promising treatment target for deadly brain cancers

Scientists report finding a potentially promising treatment target for aggressive and deadly high-grade brain cancers like glioblastoma. But they also say the current lack of a drug that hits the molecular target keeps it from being advanced for testing as a therapeutic strategy for patients with few treatment options.

18 Jun 2018

Scientists find novel tactic with potential for fighting medulloblastoma

Scientists have a new tactic with potential for fighting medulloblastoma, the most common and most aggressive form of brain tumor in children. The results are scheduled for publication in Cancer Cell.

12 Jun 2018

New research explores why minority children have worse cancer outcomes

New research will focus on finding better treatments for minority children with high-risk cancer malignancies - a group whose outcomes and survival rates are worse than other pediatric patients.

11 Jun 2018

Study demonstrates promise of new imaging method for precise brain cancer diagnostics

Nowadays, tumors inside the complex central nervous system remain one of the most challenging cancers to diagnose.

8 Jun 2018

International 'A' team unveils new glioblastoma atlas

It takes an "A" team to make headway against glioblastoma, a highly aggressive type of brain cancer. Glioblastoma is the most common type of malignant brain tumor in adults. In addition to the caliber of the researchers involved, in this case "A" also stands for atlas.

6 Jun 2018

FDA-approved drug for lymphoma and leukemia may help treat common type of brain tumor

New Cleveland Clinic research shows for the first time that ibrutinib, an FDA-approved drug for lymphoma and leukemia, may also help treat the most common – and deadliest – type of brain tumor.

30 May 2018

New drug-delivering nanoparticle could offer better way to treat brain tumors

Glioblastoma multiforme, a type of brain tumor, is one of the most difficult-to-treat cancers. Only a handful of drugs are approved to treat glioblastoma, and the median life expectancy for patients diagnosed with the disease is less than 15 months.

25 May 2018

Two genes play vital roles in malignant brain cancer

Two genes play important roles for the formation of malignant cancer in the brain. One gene prevents the formation of the tumor, while another gene promotes the tumor. This is shown in a new dissertation at Umeå University, Sweden.

24 May 2018

ABPI expert urges to find new 'blockbuster treatments' for brain tumors

Nearly 11,500 people are diagnosed with a brain tumor every year in the UK with fewer than 15% surviving beyond 10 years. This week’s announcement from the from the Department of Health and Social Care – following the death of Dame Tessa Jowell - that they would be doubling investment for brain cancer research to £40 million is a welcome commitment to helping achieve a goal our industry shares: finding innovative new treatments and cures for these diseases.

21 May 2018

Researchers discover medulloblastoma subtype that responds to less aggressive therapy

The youngest patients with the brain tumor medulloblastoma are among the most challenging because their rapidly developing brains limit treatment options.

17 May 2018

Study: Gadolinium deposition in brain not associated with dosage

Investigators at Children's Hospital Los Angeles have determined that in children receiving gadolinium as a contrast agent to enhance MRI examinations, signal changes attributed solely to deposition of this material in the brain are not dependent on the amount of gadolinium administered but rather these changes are seen in association with other factors such as the presence of brain tumors and treatment using brain irradiation. Results of the study were just published in the journal, Radiology.

15 May 2018

Brain Tumor News and Research

Further Reading

Genetic biomarker can help predict survival outcomes in patients with certain gliomas

Polio virus could help brain cancer patients

Phase 1 clinical trial of poliovirus therapy shows long-term survival benefit for recurrent glioblastoma

Unusual cell-to-cell communication in glioblastoma promotes aggressiveness and therapy resistance

Targeting cells involved in blood vessel formation could hinder brain tumor growth

Scientists point to potentially promising treatment target for deadly brain cancers

Scientists find novel tactic with potential for fighting medulloblastoma

New research explores why minority children have worse cancer outcomes

Study demonstrates promise of new imaging method for precise brain cancer diagnostics

International 'A' team unveils new glioblastoma atlas

FDA-approved drug for lymphoma and leukemia may help treat common type of brain tumor

New drug-delivering nanoparticle could offer better way to treat brain tumors

Two genes play vital roles in malignant brain cancer

ABPI expert urges to find new 'blockbuster treatments' for brain tumors

Researchers discover medulloblastoma subtype that responds to less aggressive therapy

Study: Gadolinium deposition in brain not associated with dosage

Researchers identify six genes that predispose carriers to develop medulloblastoma

New technology detects the 'glow' to guide brain tumor resection

New microfluidic device captures tumor-specific EVs to guide cancer diagnosis and treatment

New study evaluates expression of PD-L1 in human medulloblastoma

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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