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Synthetic compound that reads mitochondrial DNA could lead to treatments for nerve, muscle diseases

For the first time, a synthetic compound has been made that can bind to DNA in the cells' energy powerhouses, suppressing a gene associated with nerve and muscle disease.

11 Jul 2017

IBS scientists control memory by modulating synchronized brain waves during deep sleep

Have you ever tried to recall something just before going to sleep and then wake up with the memory fresh in your mind? While we absorb so much information during the day consciously or unconsciously, it is during shut eye that a lot of facts are dispatched to be filed away or fall into oblivion.

6 Jul 2017

New technique can help predict and combat potential pandemic virus

By developing a new technique for labeling the gene segments of influenza viruses, researchers now know more about how influenza viruses enter the cell and establish cell co-infections - a major contributing factor to potential pandemic development.

5 Jul 2017

Scientists identify neurons that play crucial roles in connecting emotions and sleep

You may have experienced sleepless nights when you were anxious, stressed or too excited. Such emotions are well-known to affect wakefulness and can even cause insomnia, though the underlying mechanisms in our brain have still been unclear.

3 Jul 2017

UA researcher’s findings on estrogen may lead to promising treatment for hot flashes

Fifteen years ago, Dr. Naomi Rance was at work when she experienced her first hot flash. Rance, a physician and researcher at the University of Arizona College of Medicine - Tucson, took note.

29 Jun 2017

Scientists use supercomputers to test new techniques for early cancer detection

An important factor in fighting cancer is the speed at which the disease can be identified, diagnosed and treated.

28 Jun 2017

Study provides better knowledge about healthcare burden of mitochondrial diseases

Mitochondrial diseases are a diverse group of disorders caused by mutated genes that impair energy production in a patient's cells, often with severe effects.

28 Jun 2017

Study: Gadolinium may accumulate in brain tissues of patients without intracranial abnormalities

Minute traces of gadolinium, the contrast agent used to enhance MR images, are often retained in the brain tissue of patients years after undergoing MRI. Some studies have suggested this deposition was limited to patients with underlying brain pathology, such as a tumor or infection.

28 Jun 2017

Human colon organoids fill gap in effectively modeling common GI diseases

Scientists used human pluripotent stem cells to generate human embryonic colons in a laboratory that function much like natural human tissues when transplanted into mice, according to research published June 22 in Cell Stem Cell.

22 Jun 2017

Prenatal exposure to pain-relieving drug can impair development of male behavior

Paracetamol is popular for relieving pain. But if you are pregnant, you should think twice before popping these pills according to the researchers in a new study.

22 Jun 2017

Researchers examine formation of functional amyloids by bacteria in real time

A team of scientists from the VIB lab of Han Remaut and the lab of Yves Dufrêne at UCL Louvain-La-Neuve collaborated on a study of functional amyloids -protein aggregates with the typical amyloid structure that do not lead to disease but rather serve a dedicated biological function.

21 Jun 2017

Researchers identify new disease gene for early-onset axonal neuropathy and mild intellectual disability

Research group from the University of Helsinki, Finland, has identified a new disease gene for early-onset axonal neuropathy and mild intellectual disability through an international research network, which was brought together by "Tinder for geneticists".

20 Jun 2017

Cells key to blood vessel formation can also produce tumors and enable their spread

While it's widely held that tumors can produce blood vessels to support their growth, scientists now have evidence that cells key to blood vessel formation can also produce tumors and enable their spread.

20 Jun 2017

Penn study reveals new molecular pilot light required to turn on brown fat furnace

As we bask in the summer heat, it is easy to take for granted that humans are also prepared for the cold of winter, with overcoats in the closet and home heating systems ready to be fired up as an added assurance against falling temperatures.

15 Jun 2017

Study shows how RNA splicing errors may trigger development of ALS, FTD

The most frequent genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD)- rare and related neurological disorders marked by progressive deterioration of motor or cognitive abilities- may be due to errors in RNA splicing, an intermediary step for translating genetic instructions into functional proteins.

14 Jun 2017

KAUST-led researchers reveal epigenetic mechanism for gene regulation

An epigenetic mechanism regulating gene activity has been revealed by a KAUST-led international team of researchers investigating interactions between the human genome and its environment in adult tissues.

12 Jun 2017

Researchers who study HED identify mechanism that may be disrupted in male pattern baldness

It is almost axiomatic in medicine that the study of rare disorders informs the understanding of more common, widespread ailments.

8 Jun 2017

Research reveals link between POMC neurons and release of insulin by the pancreas

The brain is key in the regulation of appetite, body weight and metabolism. Specifically, there is a small group of hypothalamus neurons, called POMC, that detect and integrate signals that inform on the energy state of the organism and activate the appropriate physiological responses.

8 Jun 2017

Natural sugar may trigger immune system to treat atherosclerosis, study finds

Researchers have long sought ways to harness the body's immune system to treat disease, especially cancer.

7 Jun 2017

Study suggests promising therapeutic strategy for childhood brain tumor

A study published in Molecular Cancer Research reveals that a tumor suppressor gene p16 is turned off by a histone mutation (H3.3K27M), which is found in up to 70 percent of childhood brain tumors called diffuse intrinsic pontine glioma (DIPG).

6 Jun 2017

Cell Nucleus News and Research

Synthetic compound that reads mitochondrial DNA could lead to treatments for nerve, muscle diseases

IBS scientists control memory by modulating synchronized brain waves during deep sleep

New technique can help predict and combat potential pandemic virus

Scientists identify neurons that play crucial roles in connecting emotions and sleep

UA researcher’s findings on estrogen may lead to promising treatment for hot flashes

Scientists use supercomputers to test new techniques for early cancer detection

Study provides better knowledge about healthcare burden of mitochondrial diseases

Study: Gadolinium may accumulate in brain tissues of patients without intracranial abnormalities

Human colon organoids fill gap in effectively modeling common GI diseases

Prenatal exposure to pain-relieving drug can impair development of male behavior

Researchers examine formation of functional amyloids by bacteria in real time

Researchers identify new disease gene for early-onset axonal neuropathy and mild intellectual disability

Cells key to blood vessel formation can also produce tumors and enable their spread

Penn study reveals new molecular pilot light required to turn on brown fat furnace

Study shows how RNA splicing errors may trigger development of ALS, FTD

KAUST-led researchers reveal epigenetic mechanism for gene regulation

Researchers who study HED identify mechanism that may be disrupted in male pattern baldness

Research reveals link between POMC neurons and release of insulin by the pancreas

Natural sugar may trigger immune system to treat atherosclerosis, study finds

Study suggests promising therapeutic strategy for childhood brain tumor

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