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Cancer diagnostic capacity should be ramped up to avoid unnecessary deaths, say researchers

Delays to cancer referral through reduced use of the urgent GP referral pathway during the coronavirus pandemic could result in more than a thousand additional deaths in England, a new study reports.

22 Jul 2020

Study: Luminescent substance enables accurate observation of different areas of the organism

A luminescent fluid made up of nanoparticles that allows more accurate observation of different areas of the organism has been developed by a research team from the Colloidal Materials group of the Institute of Materials Science of Seville (a CSIC-University of Seville joint centre) in collaboration with the Institute of Materials Science of Aragon, the Andalusian Centre of Medicine and Biotechnology (BIONAND) and the Spanish National Accelerator Centre (CNA).

20 Jul 2020

Study shows how radiotherapy alters the behavior of immune cells in glioblastoma tumors

A Ludwig Cancer Research study has dissected how radiotherapy alters the behavior of immune cells known as macrophages found in glioblastoma (GBM) tumors and shown how these cells might be reprogrammed with an existing drug to suppress the invariable recurrence of the aggressive brain cancer.

16 Jul 2020

Tobacco smoking and vaping nicotine may exacerbate COVID-19 inflammation

Researchers in San Diego have conducted a study showing that both smoking and the use of e-cigarettes containing nicotine and flavorings may critically exacerbate inflammation in cases of coronavirus disease 2019 (COVID-19) and significantly worsen clinical outcomes.

14 Jul 2020

People with accelerated biological age at increased risk of COVID-19 symptom severity and mortality

Now, a new study published on the preprint server medRxiv in July 2020 discusses the explanation in terms of the biological aging markers in patients with severe disease, rather than the chronological age.

13 Jul 2020

DNA resection pathways are highly specific, shows study

Our cells are constantly dividing, and as they do, the DNA molecule - our genetic code - sometimes gets broken. DNA has twin strands, and a break in both is considered especially dangerous.

7 Jul 2020

Researchers uncover a potentially promising strategy to target brain tumors

Gliomas with mutations in what are called the isocitrate dehydrogenase (IDH) genes are the most common brain tumors diagnosed in younger adults aged 18 to 45 years.

30 Jun 2020

Smart MRI scan used for heart disease can help assess aggressive cancers in children

A type of smart MRI scan used in people with heart disease could help assess whether children's cancers are especially aggressive and spot early signs that targeted treatments are working, a new study suggests.

29 Jun 2020

Study identifies small molecule inhibitors of SARS-CoV-2 which block key cellular kinases

Antiviral drug screen of kinase inhibitors, which was done by researchers from the University of California and Cedars-Sinai Medical Center, identified cellular signaling pathways critical for SARS-CoV-2 replication and revealed an important mechanism of host-pathogen interaction vital for further drug research. Their results are available on the bioRxiv* preprint server.

28 Jun 2020

New technique helps measure dNTP concentrations with greater sensitivity

A highly sensitive and easy-to-use technique applicable for tissue samples can be useful, for example, to researchers specialised in mitochondrial diseases and cancer.

24 Jun 2020

Massive proteomics investigation of COVID-19 infection

Researchers from Germany and Switzerland revealed functional effects of individual severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins on cellular level after infection. They placed the findings into the context of host signaling pathways in order to identify vulnerable parts of the virus amenable to treatment. The study is currently available on the bioRxiv preprint server.

21 Jun 2020

Differences in accumulation of genetic mutations could help predict lifespan, fertility

Differences in the rate that genetic mutations accumulate in healthy young adults could help predict the remaining lifespan in both sexes and the remaining years of fertility in women, according to the University of Utah Health scientists.

19 Jun 2020

Scientists use CRISPR tool to make rapid, precise cuts in genomic material

In a series of experiments using human cancer cell lines, scientists at Johns Hopkins Medicine say they have successfully used light as a trigger to make precise cuts in genomic material rapidly, using a molecular scalpel known as CRISPR, and observe how specialized cell proteins repair the exact spot where the gene was cut.

18 Jun 2020

DNA Damage News and Research

Cancer diagnostic capacity should be ramped up to avoid unnecessary deaths, say researchers

Study: Luminescent substance enables accurate observation of different areas of the organism

Study shows how radiotherapy alters the behavior of immune cells in glioblastoma tumors

Tobacco smoking and vaping nicotine may exacerbate COVID-19 inflammation

People with accelerated biological age at increased risk of COVID-19 symptom severity and mortality

DNA resection pathways are highly specific, shows study

Researchers uncover a potentially promising strategy to target brain tumors

Smart MRI scan used for heart disease can help assess aggressive cancers in children

Study identifies small molecule inhibitors of SARS-CoV-2 which block key cellular kinases

New technique helps measure dNTP concentrations with greater sensitivity

Massive proteomics investigation of COVID-19 infection

Differences in accumulation of genetic mutations could help predict lifespan, fertility

Scientists use CRISPR tool to make rapid, precise cuts in genomic material

Persistent DNA damage in the placenta can affect embryonic growth

Study reveals protein responsible for vulnerability in cancer cells

New insights on DNA replication can help develop novel cancer treatments

Researchers identify enzyme essential for intestinal epithelial differentiation

Study investigates combined effects of cancer therapy and inherited genetics

Researchers discover novel gene involved in DNA damage repair and male fertility

Study resolves contradictions surrounding p53 gene's role in pluripotent stem cell differentiation

Understanding the DNA Damage Response in Innate Immunity eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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