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Researchers explore a novel method to isolate monoclonal antibodies from COVID-19 convalescents infected with SARS-CoV-2 variants

Researchers developed a novel high-throughput method to obtain monoclonal antibodies from COVID-19 individuals infected with SARS-CoV-2 ancestral strain Wuhan-Hu-1 and the Beta or Gamma variants.

1 Apr 2022

Scientists evaluate the SARS-CoV-2 neutralizing ability of two-dose BNT162b2 vaccination

A new study analyzed the SARS-CoV-2 neutralizing capacity of sera samples from two-dose BNT162b2 vaccinated Japanese subjects.

1 Apr 2022

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

Researchers examined the role of sialic acid-binding immunoglobulin-type lectins-1, a myeloid cell-specific receptor, in facilitating SARS-CoV-2 infection of ACE2-deficient macrophages and its effect on pro-inflammatory cytokine expression.

1 Apr 2022

The mucosal antibody response to SARS-CoV-2

Researchers determine mucosal SARS-CoV-2-specific antibody levels and their neutralizing effect in pediatric and adult patients.

31 Mar 2022

Risk of breakthrough infections by SARS-CoV-2 Omicron and Delta variants in fully vaccinated adults

In a new study, researchers determined the risk of breakthrough infections by SARS-CoV-2 Omicron and Delta variants in fully vaccinated individuals.

31 Mar 2022

Study determines the molecular signatures of monocytes and regulatory T cells in the circulating blood of COVID-19 patients

Researchers examined the unique clusters of monocytes and regulatory T cells in the circulating blood from convalescent COVID-19 patients over a prolonged period after recovery, using scRNA sequencing.

31 Mar 2022

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Researchers evaluated the protection conferred by booster doses of the preclinical version of the Moderna mRNA-1273 vaccine and a SARS-CoV-2 Omicron variant-matched vaccine against Omicron infections in mice.

31 Mar 2022

Prevalence of breastmilk feeding among people with SARS-CoV-2 infection during pregnancy

Researchers evaluated the association between breastmilk feeding and the time of maternal SARS-CoV-2 infection during pregnancy and the rooming-in status during the hospitalization for delivery.

31 Mar 2022

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

Researchers bioengineered a divalent fusion vaccine by combining the immunogenic region of the nucleocapsid protein and the receptor-binding domain of the spike protein of SARS-CoV-2.

30 Mar 2022

The potential efficacy of nasal nanoparticle COVID-19 vaccines

The current paper reviews progress in this field regarding nasal nanoparticle vaccines for COVID-19.

30 Mar 2022

Evaluating serological responses to repeated COVID-19 vaccination in kidney transplant recipients

Researchers analyzed whether repeated vaccinations against COVID-19 increase serological response in non-responding kidney transplant recipients.

29 Mar 2022

Results of Phase 3 Nanocovax SARS-CoV-2 vaccine trial suggest robust effectiveness

A new study presented the findings of the Phase 3 trial of the Nanocovax coronavirus disease 2019 (COVID-19) vaccine.

29 Mar 2022

Natural SARS-CoV-2 antibodies persist for six months in children

Researchers investigate the presence of antibodies against SARS-CoV-2 in children between the ages of five and 19 after infection.

28 Mar 2022

Study investigates room-temperature stable, self-amplifying RNA vaccine against SARS-CoV-2

Researchers applied a previously developed thermostable self-amplifying ribonucleic acid vaccine to COVID-19.

28 Mar 2022

Durability and functionality of the humoral and T-cell response to SARS-CoV-2 and its variants in recovered patients

A recent study investigated the potency and functionality of T-cell and humoral responses against the SARS-CoV-2 wild-type strain and its variants.

28 Mar 2022

Neutralization of BA.1 and BA.2 Omicron variants with monoclonal antibodies

A new research paper published as an early release manuscript in the Nature Medicine journal compares the sensitivity of this strain as well as the earlier Delta and the newer BA.2 to therapeutic mAbs.

27 Mar 2022

How the timing and dose of different types of passive antibody treatments predict protection from SARS-CoV-2 infection

A new study has focussed on conducting a systematic search of the literature and aggregated data associated with randomized control trials of passive antibody therapy.

25 Mar 2022

Evusheld™ found to poorly neutralize Omicron in kidney transplant patients

Researchers evaluated the neutralizing antibody titers and anti-receptor-binding domain immunoglobulin G titers in sera of kidney transplant recipients who were vaccinated against COVID-19 and treated with 300 mg dosage of Evusheld™

25 Mar 2022

Adaptive immunity against SARS-CoV-2 is persistent and robust in COVID-convalescent children

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection incites adaptive cellular immune responses. In many SARS-CoV-2 studies, peripheral blood is analyzed to study the immune responses. Now, a new study under consideration at the Nature Portfolio Journal analyzes the peripheral blood, tonsils, and adenoids of children to understand local and systemic immune responses to SARS-CoV-2.

25 Mar 2022

IgG Fc glycosylation: A marker for severe COVID-19

Researchers suggest that low anti-spike IgG1 glycosylation, sialyation, and high bisection are markers of severe COVID-19.

24 Mar 2022

Immunoglobulin News and Research

Researchers explore a novel method to isolate monoclonal antibodies from COVID-19 convalescents infected with SARS-CoV-2 variants

Scientists evaluate the SARS-CoV-2 neutralizing ability of two-dose BNT162b2 vaccination

Study explores molecular mechanisms underlying SARS-CoV-2 infection of macrophages and the induction of pro-inflammatory cytokines

The mucosal antibody response to SARS-CoV-2

Risk of breakthrough infections by SARS-CoV-2 Omicron and Delta variants in fully vaccinated adults

Study determines the molecular signatures of monocytes and regulatory T cells in the circulating blood of COVID-19 patients

Messenger ribonucleic acid boosters shown to be effective against Omicron infections in mice

Prevalence of breastmilk feeding among people with SARS-CoV-2 infection during pregnancy

Divalent SARS-CoV-2 fusion vaccine found to be effective in mice

The potential efficacy of nasal nanoparticle COVID-19 vaccines

Evaluating serological responses to repeated COVID-19 vaccination in kidney transplant recipients

Results of Phase 3 Nanocovax SARS-CoV-2 vaccine trial suggest robust effectiveness

Natural SARS-CoV-2 antibodies persist for six months in children

Study investigates room-temperature stable, self-amplifying RNA vaccine against SARS-CoV-2

Durability and functionality of the humoral and T-cell response to SARS-CoV-2 and its variants in recovered patients

Neutralization of BA.1 and BA.2 Omicron variants with monoclonal antibodies

How the timing and dose of different types of passive antibody treatments predict protection from SARS-CoV-2 infection

Evusheld™ found to poorly neutralize Omicron in kidney transplant patients

Adaptive immunity against SARS-CoV-2 is persistent and robust in COVID-convalescent children

IgG Fc glycosylation: A marker for severe COVID-19

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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