Psychosis News and Research

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Psychosis means abnormal condition of the mind, and is a generic psychiatric term for a mental state often described as involving a "loss of contact with reality". People suffering from psychosis are said to be ''psychotic.''

Janssen announces submission of NDA for three-month paliperidone palmitate

Janssen Research & Development, LLC today announced the submission of a New Drug Application (NDA) for three-month atypical antipsychotic paliperidone palmitate to the U.S. Food and Drug Administration. The NDA seeks approval for the medication as a treatment for schizophrenia in adults.

19 Nov 2014

Suicidal ideation link to suicide strong in schizophrenia spectrum disorders

The association between suicidal ideation and later suicide is much stronger in patients with schizophrenia spectrum psychosis than in those with mood disorders, show results of a systematic meta-analysis.

13 Nov 2014

Cue processing altered in siblings of schizophrenia patients

The siblings of patients with schizophrenia have altered activity in the ventral striatum during reward anticipation and receipt, a study shows.

6 Nov 2014

ISBD Task Force examines suicide predictors

The International Society for Bipolar Disorders Task Force on Suicide has published a meta-analysis of predictors of suicide attempts and deaths.

30 Oct 2014

Genetics underpin bullying victimisation influence on paranoia

Bullying victimisation in childhood may indicate genetic risk for later psychosis, rather than being an environmental trigger, say UK researchers.

22 Oct 2014

Aspirin can improve efficacy of schizophrenia treatments

A new study shows that some anti-inflammatory medicines, such as aspirin, estrogen, and Fluimucil, can improve the efficacy of existing schizophrenia treatments. This work is being presented at the European College of Neuropsychopharmacology conference in Berlin.

20 Oct 2014

Cannabis use during adolescence: an interview with Dr Edmund Silins

We know quite a lot about the effects of cannabis on the body and brain but there is still a need to better understand its impact on the health, well-being and development of long term users.

20 Oct 2014

Groundbreaking study tracks precise path of rabies to the central nervous system

Rabies causes acute inflammation of the brain, producing psychosis and violent aggression. The virus, which paralyzes the body's internal organs, is always deadly for those unable to obtain vaccines in time. Some 55,000 people die from rabies every year.

7 Oct 2014

Psychotic disorders confer ‘staggering’ increase in unnatural death risk

Mortality among patients during the first 10 years after first-episode psychosis is marked by a huge increase in the rate of unnatural death relative to the general population, a UK study shows.

2 Oct 2014

Neuropsychiatric symptoms variable in early Parkinson’s disease

The prevalence of neuropsychiatric symptoms is increased in patients with early Parkinson’s disease, although many remain stable over time, shows follow-up of the Parkinson’s Progression Markers Initiative.

29 Sep 2014

Researchers take major step forward in accurate diagnosis of people experiencing psychosis

A study led by University of North Carolina at Chapel Hill researchers represents an important step forward in the accurate diagnosis of people who are experiencing the earliest stages of psychosis.

22 Sep 2014

Researchers identify control mechanism for mood disorders

Researchers at University of California, San Diego School of Medicine have identified a control mechanism for an area of the brain that processes sensory and emotive information that humans experience as "disappointment."

19 Sep 2014

FDA approves Contrave extended-release tablets for chronic weight management

Takeda Pharmaceuticals U.S.A., Inc. and Orexigen® Therapeutics, Inc. jointly announced today that the U.S. Food and Drug Administration has approved Contrave® extended-release tablets as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adults with an initial body mass index of 30 kg/m2 or greater (obese), or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition.

11 Sep 2014