Ribonucleic Acid News and Research

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A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

Research investigates the susceptibility of seven bat species to SARS-CoV-2 by expressing their ACE2 receptor in a non-permissive avian cell line. The study found that all seven bat species were susceptible to SARS-CoV-2, but the level of virus replication differed between bat species and virus variants.

24 Apr 2023

Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

A self-amplifying replicon RNA vaccine against SARS-CoV-2 can elicit durable and protective immunity in pigtail macaques, even after neutralizing antibody responses have waned to undetectable levels.

23 Apr 2023

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

CMPK2 identified as a potential pan-flavivirus inhibitor, restricting virus replication and providing a basis for developing new antiviral treatments.

23 Apr 2023

An exploration of the pathophysiological factors and abnormalities of coagulation of long-COVID

Researchers explored the pathophysiological variables and coagulation abnormalities associated with long coronavirus disease (COVID).

21 Apr 2023

Researchers develop a new powerful resource to study extracellular RNA

An international team led by researchers at Baylor College of Medicine with the National Institutes of Health Extracellular RNA Communication Consortium and the Bogdan Mateescu laboratory at the ETH Zürich and University of Zürich has developed a new powerful resource to study extracellular RNA (exRNA), a novel form of cell-to-cell communication.

20 Apr 2023

Observational cohort study of long COVID among 2 million elderly adults

Research estimates the incidence of long COVID and long Flu among Medicare patients using the World Health Organization (WHO) consensus definition. The study compares the incidence, symptomatology, and healthcare utilization between long COVID and long flu patients.

20 Apr 2023

Understanding the probable transmission of SARS-CoV-2 from lion to zookeepers

Researchers explored the possible transmission of SARS-CoV-2 to zoo employees from an African lion.

19 Apr 2023

Unlocking the potential of RNA lipid nanoparticles to revolutionize cancer treatment

This paper discusses the use of RNA lipid nanoparticles for cancer immunotherapy, which has shown promising results in clinical use. However, only a small percentage of patients respond to existing immunotherapies, and the paper explores opportunities for improvement.

18 Apr 2023

New DCFHP-alum COVID-19 vaccine candidate shows durable, broad-spectrum protection in non-human primates

The newly developed DCFHP-alum COVID-19 vaccine candidate is affordable and effective for mass vaccination.

18 Apr 2023

Edible mushrooms: the role of antioxidant compounds as potential candidates for neurodegenerative disease prevention and treatment

Researchers evaluated whether edible mushrooms aid in preventing neurodegenerative diseases.

18 Apr 2023

Consuming mangos boosts gut microbiome diversity: Benefits for overweight and obese individuals

In a recent study published in the journal Food Science and Nutrition, researchers at San Diego State University investigated how consuming fresh mango affects gut health and microbiome.

17 Apr 2023

Lactobacillus probiotics improve vaginal health in asymptomatic women

This study investigated the effect of administering Lactobacillus probiotics (LBPs) on vaginal dysbiosis in asymptomatic women. The results showed that oral intake of LBPs improved vaginal health in women with high Nugent scores.

17 Apr 2023

Vaccine component BNT162b4 enhances T-cell immunity against SARS-CoV-2 variants for reduced COVID-19 disease severity

Researchers designed a novel messenger ribonucleic acid (mRNA) vaccine component designated BNT162b4.

17 Apr 2023

Study highlights the importance of bivalent mRNA booster vaccination in populations at high risk of severe COVID-19

Researchers evaluated whether bivalent mRNA vaccine booster reduced COVID-19-related hospitalizations and mortality.

17 Apr 2023

Pregnant women show unique immune response to COVID-19

Researchers compare the adaptive, innate, and humoral immune responses between pregnant and non-pregnant women with COVID-19.

16 Apr 2023

Study uncovers a novel fold within the SARS-CoV-2 replication co-factor non-structural protein 9

Researchers present the crystal structure of an anti-non-structural protein 9 specific nanobody in complex with the SARS-CoV-2 nsp9.

15 Apr 2023

Maternal psychosocial stress may impact the developing infant gut microbiome

Researchers determined the impact of the psychosocial stress experienced by the mother on the gut microbiome of the infant.

15 Apr 2023

Monovalent and bivalent COVID boosters provide strong protection against severe outcomes in older adults

Researchers examined the effectiveness of SARS-CoV-2 booster doses in preventing severe Omicron infection outcomes.

15 Apr 2023

Study develops a novel intranasal influenza virus-vectored vaccine for SARS-CoV-2

Researchers developed a novel intranasal vaccine candidate for coronavirus disease 2019 (COVID-19).

14 Apr 2023

Using tiny bubbles to improve gene therapy

Beyond vaccines, mRNA offers immense potential to fight disease, but targeting the genetic material to specific diseased cells is challenging - requiring a new method.

11 Apr 2023

Ribonucleic Acid News and Research

A rapid and affordable in vitro model to test SARS-CoV-2 susceptibility in animal species

Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

Study reveals CMPK-2 protein-coding gene as a potent inhibitor of flaviviruses

An exploration of the pathophysiological factors and abnormalities of coagulation of long-COVID

Researchers develop a new powerful resource to study extracellular RNA

Observational cohort study of long COVID among 2 million elderly adults

Understanding the probable transmission of SARS-CoV-2 from lion to zookeepers

Unlocking the potential of RNA lipid nanoparticles to revolutionize cancer treatment

New DCFHP-alum COVID-19 vaccine candidate shows durable, broad-spectrum protection in non-human primates

Edible mushrooms: the role of antioxidant compounds as potential candidates for neurodegenerative disease prevention and treatment

Consuming mangos boosts gut microbiome diversity: Benefits for overweight and obese individuals

Lactobacillus probiotics improve vaginal health in asymptomatic women

Vaccine component BNT162b4 enhances T-cell immunity against SARS-CoV-2 variants for reduced COVID-19 disease severity

Study highlights the importance of bivalent mRNA booster vaccination in populations at high risk of severe COVID-19

Pregnant women show unique immune response to COVID-19

Study uncovers a novel fold within the SARS-CoV-2 replication co-factor non-structural protein 9

Maternal psychosocial stress may impact the developing infant gut microbiome

Monovalent and bivalent COVID boosters provide strong protection against severe outcomes in older adults

Study develops a novel intranasal influenza virus-vectored vaccine for SARS-CoV-2

Using tiny bubbles to improve gene therapy

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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